E. Lewis

发表

N-Succinyl-(beta-alanyl-L-leucyl-L-alanyl-L-leucyl)doxorubicin: an extracellularly tumor-activated prodrug devoid of intravenous acute toxicity.

D. Shochat, V. Dubois, A. Trouet, 2001, Journal of medicinal chemistry.

Design and synthesis of an orally bioavailable and selective peptide epoxyketone proteasome inhibitor (PR-047).

S. Demo, M. Aujay, T. Muchamuel, 2009, Journal of medicinal chemistry.

Large Competitive Kinetic Isotope Effects in Human 15-Lipoxygenase Catalysis Measured by a Novel HPLC Method

T. Holman, E. Johansen, E. Lewis, 1999 .

Antitumor activity of a kinesin inhibitor.

K. Wood, J. Finer, J. Mak, 2004, Cancer research.

Site-directed mutagenesis of glutamate-166 in beta-lactamase leads to a branched path mechanism.

A. Fink, E. Lewis, A. Tan, 1994, Biochemistry.

A point mutation leads to altered product specificity in β-lactamase catalysis

A. Fink, E. Lewis, K. Winterberg, 1997 .

The Selective Proteasome Inhibitor Carfilzomib Is Well Tolerated in Experimental Animals with Dose Intensive Administration

M. Aujay, T. Muchamuel, M. Bennett, 2008 .

Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer

Jennifer B Dennison, S. Demo, M. Bennett, 2014, Molecular Cancer Therapeutics.

Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome.

S. Demo, M. Aujay, M. Bennett, 2007, Cancer research.

Abstract 1416: CB-839, a novel potent and selective glutaminase inhibitor, has broad antiproliferative activity in cell lines derived from both solid tumors and hematological malignancies

S. Demo, Dong Zhang, M. Bennett, 2014 .

Abstract 1877: Anti-tumor activity of novel, potent, selective and orally-bioavailable glutaminase inhibitors.

S. Demo, A. Richardson, M. Bennett, 2013 .

CPI-0004Na An extracellularly tumor-activated prodrug of doxorubicin

G. Yarranton, V. Dubois, A. Trouet, 2000 .

Small Molecule Therapeutics Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer

S. Demo, M. Bennett, F. Parlati, 2014 .

A pyrolysis product, anhydroecgonine methyl ester (methylecgonidine), is in the urine of cocaine smokers.

P. Jacob, Reese T. Jones, R. Jones, 1990, Journal of analytical toxicology.

Enzyme-induced strain/distortion in the ground-state ES complex in beta-lactamase catalysis revealed by FTIR.

A. Fink, G. Cope, E. Lewis, 2000, Biochemistry.