W. Padgett

发表

Maitotoxin-elicited calcium influx in cultured cells. Effect of calcium-channel blockers.

J. Lueders, F. Gusovsky, J. Daly, 1995, Biochemical pharmacology.

Effects of the amphiphilic peptides melittin and mastoparan on calcium influx, phosphoinositide breakdown and arachidonic acid release in rat pheochromocytoma PC12 cells.

J. Daly, O. Choi, W. Padgett, 1992, The Journal of pharmacology and experimental therapeutics.

8‐(3‐Chlorostyryl)caffeine (CSC) is a selective A2‐adenosine antagonist in vitro and in vivo

K. Jacobson, J. Daly, W. Padgett, 1993, FEBS letters.

Ibogaine: a potent noncompetitive blocker of ganglionic/neuronal nicotinic receptors.

J. Daly, W. Padgett, B. Badio, 1997, Molecular pharmacology.

Interaction of pumiliotoxin B with an "alkaloid-binding domain" on the voltage-dependent sodium channel.

F. Gusovsky, J. Daly, W. Padgett, 1992, Molecular pharmacology.

Decahydroquinoline alkaloids: Noncompetitive blockers for nicotinic acetylcholine receptor-channels in pheochromocytoma cells andTorpedo electroplax

J. Daly, R. Aronstam, P. Mccloskey, 1991, Neurochemical Research.

Structure-activity relationships for N6-substituted adenosines at a brain A1-adenosine receptor with a comparison to an A2-adenosine receptor regulating coronary blood flow.

J. Daly, W. Padgett, R. Thompson, 1986, Biochemical pharmacology.

A2A adenosine receptors from rat striatum and rat pheochromocytoma PC12 cells: characterization with radioligand binding and by activation of adenylate cyclase.

K. Jacobson, J. Daly, I. Hide, 1992, Molecular pharmacology.

A functionalized congener approach to adenosine receptor antagonists: amino acid conjugates of 1,3-dipropylxanthine.

K. Jacobson, J. Daly, K. Kirk, 1986, Molecular pharmacology.

Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors.

K. Jacobson, J. Daly, K. Kirk, 1985, Journal of medicinal chemistry.

Fluoronorepinephrines: specific agonists for the activation of alpha and beta adrenergic-sensitive cyclic AMP-generating systems in brain slices.

J. Daly, K. Kirk, W. Padgett, 1980, The Journal of pharmacology and experimental therapeutics.

Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors.

J. Daly, W. Padgett, M. Shamim, 1986, Journal of medicinal chemistry.

Tetrahydrobenzothiophenone derivatives as a novel class of adenosine receptor antagonists.

K. Jacobson, D. Shi, J. Daly, 1996, Journal of medicinal chemistry.

5,8-Disubstituted indolizidines: A new class of noncompetitive blockers for nicotinic receptor-channels

J. Daly, A. Holmes, R. Aronstam, 1991, Neurochemical Research.

Activation and desensitization of rat A3‐adenosine receptors by selective adenosine derivatives and xanthine‐7‐ribosides

K. Jacobson, C. Hoffmann, J. Daly, 1998, Drug development research.

Pyrazolopyridines: Effect of structural alterations on activity at adenosine‐ and GABAA‐receptors

D. Shi, J. Daly, K. Hutchinson, 1997 .

A SURVEY OF NONXANTHINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS.

K. Jacobson, G. Stiles, J. Daly, 1996, Nucleosides & nucleotides.

Degeneration of CA1 neurons in hippocampus after ischemia in Mongolian gerbils: Cyclic AMP-systems

J. Daly, W. Padgett, I. Karnushina, 1983, Brain Research.

Synthesis and biological properties of 2-, 5-, and 6-fluoronorepinephrines.

J. Daly, D. Cantacuzène, K. Kirk, 1979, Journal of medicinal chemistry.

Cyclic AMP-generating systems: regional differences in activation by adrenergic receptors in rat brain

J. Daly, K. Kirk, W. Padgett, 1981, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Cardiovascular actions of adenosines, but not adenosine receptors, differ in rat and guinea pig.

J. Daly, M. Ueeda, W. Padgett, 1991, Life sciences.

Molecular probes for extracellular adenosine receptors.

K. Jacobson, J. Daly, D. Ukena, 1987, Biochemical pharmacology.

Synthesis and nicotinic activity of epiboxidine: an isoxazole analogue of epibatidine.

J. Daly, H. M. Garraffo, W. Padgett, 1997, European journal of pharmacology.

Non-xanthine heterocycles: activity as antagonists of A1- and A2-adenosine receptors.

K. Jacobson, J. Daly, D. Ukena, 1988, Biochemical pharmacology.

Syntheses of (R)- and (S)-2- and 6-fluoronorepinephrine and (R)- and (S)-2- and 6-fluoroepinephrine: effect of stereochemistry on fluorine-induced adrenergic selectivities.

J. Daly, G. Haufe, K. Laue, 2000, Journal of medicinal chemistry.

Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells.

J. Daly, K. Seamon, W. Padgett, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Mesoionic xanthine analogues: antagonists of adenosine receptors.

R. Glennon, J. Daly, W. Padgett, 1984, Journal of medicinal chemistry.

Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists.

Kenneth A Jacobson, K. Jacobson, C. Müller, 2002, Journal of medicinal chemistry.

Effect of fluorine substitution on the adrenergic properties of 3-(tert-butylamino)-1-(3,4-dihydroxyphenoxy)-2-propanol.

F. Gusovsky, J. Daly, A. Adejare, 1991, Journal of medicinal chemistry.

Activation of Cyclic AMP‐Generating Systems in Brain Membranes and Slices by the Diterpene Forskolin: Augmentation of Receptor‐Mediated Responses

J. Daly, K. Seamon, W. Padgett, 1982, Journal of neurochemistry.

1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors.

J. Daly, W. Padgett, M. Shamim, 1985, Journal of medicinal chemistry.

Maitotoxin: effects on calcium channels, phosphoinositide breakdown, and arachidonate release in pheochromocytoma PC12 cells.

F. Gusovsky, J. Daly, O. Choi, 1990, Molecular pharmacology.

Caffeine Analogs: Effects on Ryanodine-Sensitive Calcium-Release Channels and GABAA Receptors

D. Shi, J. Daly, W. Padgett, 2003, Cellular and Molecular Neurobiology.

Syntheses and adrenergic activities of ring-fluorinated epinephrines.

F. Gusovsky, J. Daly, A. Adejare, 1988, Journal of medicinal chemistry.

Subclasses of adenosine receptors in the central nervous system: Interaction with caffeine and related methylxanthines

J. Daly, W. Padgett, P. Butts-Lamb, 1983, Cellular and Molecular Neurobiology.

Absence of tetrodotoxins in a captive-raised riparian frog, Atelopus varius.

J. Daly, R. Saunders, W. Padgett, 1997, Toxicon : official journal of the International Society on Toxinology.

Interaction of Anticonvulsant Drugs with Adenosine Receptors in the Central Nervous System

W. Padgett, R. Weir, J. W. Daly, 1984, Epilepsia.

Caffeine and theophylline analogues: correlation of behavioral effects with activity as adenosine receptor antagonists and as phosphodiesterase inhibitors.

J. Daly, O. Choi, W. Padgett, 1988, Life sciences.

Analogs of caffeine: antagonists with selectivity for A2 adenosine receptors.

J. Daly, D. Ukena, W. Padgett, 1986, Life sciences.

Spiropyrrolizidines: a new class of blockers of nicotinic receptors.

J. Daly, K. Hutchinson, Y. Shin, 1996, Biochemical pharmacology.

Pseudophrynaminol: a potent noncompetitive blocker of nicotinic receptor-channels.

J. Daly, H. M. Garraffo, W. Padgett, 1997, Biochemical pharmacology.

Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors.

J. Daly, W. Padgett, M. Shamim, 1986, Journal of medicinal chemistry.

Binary drugs: conjugates of purines and a peptide that bind to both adenosine and substance P receptors.

K. Jacobson, T. Moody, J. Daly, 1987, Journal of medicinal chemistry.

8-Aryl-and 8-cycloalkyl-1,3-dipropylxanthines: further potent and selective antagonists for A1-adenosine receptors.

J. Daly, D. Ukena, W. Padgett, 1988, Journal of medicinal chemistry.

Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions.

J. Daly, D. Ukena, W. Padgett, 1989, Journal of medicinal chemistry.

Species differences in structure‐activity relationships of adenosine agonists and xanthine antagonists at brain A1 adenosine receptors

K. Jacobson, J. Daly, D. Ukena, 1986, FEBS letters.

Agonist activity of 2- and 5'-substituted adenosine analogs and their N6-cycloalkyl derivatives at A1- and A2-adenosine receptors coupled to adenylate cyclase.

J. Daly, W. Padgett, 1992, Biochemical pharmacology.

Functionalized congeners of adenosine: preparation of analogues with high affinity for A1-adenosine receptors.

K. Jacobson, J. Daly, K. Kirk, 1985, Journal of medicinal chemistry.

Riboflavin: Inhibitory effects on receptors, G‐proteins, and adenylate cyclase

K. Jacobson, D. Shi, J. Daly, 1997, Drug development research.

6beta-Acyloxy(nor)tropanes: affinities for antagonist/agonist binding sites on transfected and native muscarinic receptors.

J. Daly, W. Padgett, X. Pei, 2000, Journal of medicinal chemistry.

Inhibition of platelet aggregation by adenosine receptor agonists

D. Shi, J. Daly, G. Cristalli, 1994, Naunyn-Schmiedeberg's Archives of Pharmacology.

Structure-activity relationships for 2-substituted adenosines at A1 and A2 adenosine receptors.

J. Daly, W. Padgett, R. Thompson, 1993, Pharmacology.

Probing the adenosine receptor with adenosine and xanthine biotin conjugates

K. Jacobson, J. Daly, K. Kirk, 1985, FEBS letters.

N6-substituted N-alkyladenosine-5'-uronamides: bifunctional ligands having recognition groups for A1 and A2 adenosine receptors.

J. Daly, D. Ukena, W. Padgett, 1986, Journal of medicinal chemistry.

8-Substituted xanthines as antagonists at A1- and A2-adenosine receptors.

K. Jacobson, J. Daly, R. Schulick, 1988, Biochemical pharmacology.

7-Deaza-9-phenyladenines. A new class of adenosine receptor antagonists.

J. Daly, W. Padgett, K. Eger, 1988, Biochemical pharmacology.

6beta-Acetoxynortropane: a potent muscarinic agonist with apparent selectivity toward M2-receptors.

J. Daly, W. Padgett, X. Pei, 1998, Journal of medicinal chemistry.