Hiroaki Saito

发表

7-Hydorxyindirubin is capable of specifically inhibiting anticancer drug-induced YB-1 nuclear translocation without showing cytotoxicity in HepG2 hepatocellular carcinoma cells.

Toru Tanaka, Shunsuke Kobayashi, Hiroaki Saito, 2021, Biochemical and biophysical research communications.

Induction of cell death in pancreatic ductal adenocarcinoma by indirubin 3'-oxime and 5-methoxyindirubin 3'-oxime in vitro and in vivo.

S. Masuda, N. Nemoto, T. Homma, 2017, Cancer letters.

5-Bromoindirubin 3'-(O-oxiran-2-ylmethyl)oxime: A long-acting anticancer agent and a suicide inhibitor for epoxide hydrolase.

T. Uchiyama, Takeshi Fujii, Hiroaki Saito, 2017, Bioorganic & medicinal chemistry.

Indirubin derivatives protect against endoplasmic reticulum stress-induced cytotoxicity and down-regulate CHOP levels in HT22 cells.

Shunsuke Kobayashi, S. Ohashi, K. Ishige, 2017, Bioorganic & medicinal chemistry letters.

Indirubin 3'-Epoxide Induces Caspase-Independent Cell Death in Human Neuroblastoma.

S. Hanada, M. Kurita, Hiroaki Saito, 2016, Biological & pharmaceutical bulletin.

Indirubin 3'-(O-oxiran-2-ylmethyl)oxime: a novel anticancer agent.

T. Uchiyama, K. Metori, Hiroaki Saito, 2015, Bioorganic & medicinal chemistry letters.

Indirubin derivatives alter DNA binding activity of the transcription factor NF-Y and inhibit MDR1 gene promoter.

Toru Tanaka, Shunsuke Kobayashi, S. Ohashi, 2014, European journal of pharmacology.

Synthesis of methoxy- and bromo-substituted indirubins and their activities on apoptosis induction in human neuroblastoma cells.

S. Hanada, Hiroaki Saito, S. Miyairi, 2011, Bioorganic & medicinal chemistry letters.

Effects of synthetic para-nonylphenol isomers administered chronically throughout pregnancy and lactation on reproductive system of mouse pups

T. Katase, T. Uchiyama, Y. Fujimoto, 2009, Archives of Toxicology.

Separation, synthesis and estrogenic activity of 4-nonylphenols: two sets of new diastereomeric isomers in a commercial mixture.

Yasuo Fujimoto, T. Katase, M. Makino, 2008, Chemosphere.

Optical Resolution and Absolute Configuration of Branched 4-Nonylphenol Isomers and Their Estrogenic Activities

D. Hashizume, T. Katase, M. Makino, 2007 .

Neuroprotective effect of S-allyl-l-cysteine derivatives against endoplasmic reticulum stress-induced cytotoxicity is independent of calpain inhibition.

M. Makishima, S. Shimba, T. Uchiyama, 2016, Journal of pharmacological sciences.

Simultaneous Analysis of Residual 4-Alkylphenols in Synthetic Resin Products for Drug and Food Use Using Head-Space Gas Chromatography-Mass Spectrometry (HS-GC/MS)

T. Nakagawa, T. Uchiyama, Y. Fujimoto, 2007 .

Is an Inhibitor or Blocker of Inactivation of Glycogen Synthase Kinase- 3β (GSK-3β) a Reliable Agent for Cancer Chemotherapy?

Hiroaki Saito, S. Miyairi, Yoshimi Ichimaru, 2016 .

Synthesis and Comparative Structure–Activity Study of Carbohydrate-Based Phenolic Compounds as α-Glucosidase Inhibitors and Antioxidants

T. Uchiyama, Hiroaki Saito, Saki Mukai, 2019, Molecules.

N–H insertion reaction via an iron carbenoid from α-diazophenylpropionate and its application to the formal total synthesis of stizolobinic acid

T. Uchiyama, Hiroki Homma, K. Mizuta, 2020 .

Molecular Sieves Catalyzed Synthesis of Phenazine 5,10-Dioxides under Solvent-Free Conditions Using Microwave Irradiation

Hiroaki Saito, S. Miyairi, T. Takabatake, 2011 .

Silica gel catalyzed synthesis of quinoxaline 1,4-dioxides under solvent-free conditions using microwave irradiation

Hiroaki Saito, S. Miyairi, T. Takabatake, 2009 .

Cinchona alkaloids induce asymmetry in the insertion reaction of thermally generated carbenes into N−H bonds

T. Uchiyama, Hiroaki Saito, S. Miyairi, 2012 .

Asymmetric intermolecular N-H insertion reaction of phenyldiazoacetates with anilines catalyzed by achiral dirhodium(2) carboxylates and cinchona alkaloids

T. Uchiyama, Hiroaki Saito, Muneharu Miyake, 2010 .

Chiral Induction by cinchona alkaloids in the rhodium(II) catalyzed O-H insertion reaction.

T. Uchiyama, Hiroaki Saito, S. Miyairi, 2010, Chemical & pharmaceutical bulletin.

Molecular Sieves Catalyzed Synthesis of Phenazine 5,10-Dioxides under Solvent-Free Conditions Using Microwave Irradiation.

Hiroaki Saito, S. Miyairi, T. Takabatake, 2011 .

Silica Gel Catalyzed Synthesis of Quinoxaline 1,4‐Dioxides under Solvent‐Free Conditions Using Microwave Irradiation.

Hiroaki Saito, S. Miyairi, T. Takabatake, 2009 .

Syntheses and estrogenic activity of 4-nonylphenol isomers.

Yasuo Fujimoto, T. Katase, M. Makino, 2008, Chemosphere.

Estrogen equivalent concentration of 13 branched para-nonylphenols in three technical mixtures by isomer-specific determination using their synthetic standards in SIM mode with GC-MS and two new diasteromeric isomers.

Yasuo Fujimoto, Yun-Seok Kim, Hideshige Takada, 2008, Chemosphere.

Effect of permeation enhancers on the in vitro percutaneous absorption of pentazocine.

T. Fukami, T. Furuishi, Toyofumi Suzuki, 2007, Biological & pharmaceutical bulletin.

Synthesis and Evaluation of Gallotannin Derivatives as Antioxidants and α-Glucosidase Inhibitors.

T. Uchiyama, Hiroaki Saito, S. Machida, 2021, Chemical and pharmaceutical bulletin.

Indirubin 3'-oxime inhibits anticancer agent-induced YB-1 nuclear translocation in HepG2 human hepatocellular carcinoma cells.

Toru Tanaka, Shunsuke Kobayashi, S. Ohashi, 2017, Biochemical and biophysical research communications.

Immunization with 3-oxododecanoyl-L-homoserine lactone-protein conjugate protects mice from lethal Pseudomonas aeruginosa lung infection.

T. Standiford, M. Ishiguro, K. Tateda, 2006, Journal of medical microbiology.

Inhibitory Effects of Indirubin-3'-oxime Derivatives on Lipid Accumulation in 3T3-L1 Cells.

T. Uchiyama, Y. Kishikawa, Hiroaki Saito, 2020, Biological & pharmaceutical bulletin.

Synthesis of Quinoxaline 1,4-Dioxides from 5,6-Diethylbenzofuroxan on Silica Gel

Hiroaki Saito, S. Miyairi, T. Takabatake, 2005 .

Synthesis of Quinoxaline 1,4‐Dioxides from 5,6‐Diethylbenzofuroxan on Silica Gel.

Hiroaki Saito, S. Miyairi, T. Takabatake, 2005 .

Chemical synthesis of the 17-propanamide derivatives of stereoisomeric Δ14-17α- and 17β-estradiols: potential 17β-hydroxysteroid dehydrogenase inhibitors.

T. Matsuzaki, Shoujiro Ogawa, T. Iida, 2011, Chemistry and Physics of Lipids.

Chiral Induction by Cinchona Alkaloids in the Rhodium(II) Catalyzed O—H Insertion Reaction.

T. Uchiyama, Hiroaki Saito, S. Miyairi, 2010 .