E. Wadman

发表

Clinical efficacy and IL-17 targeting mechanism of Indigo naturalis as a topical agent in moderate psoriasis

S. Kao, Katherine Li, Jackson Wu, 2017, BMC Complementary and Alternative Medicine.

Discovery of CC chemokine receptor-3 (CCR3) antagonists with picomolar potency.

G. Trainor, M. Covington, C. Decicco, 2005, Journal of medicinal chemistry.

CC chemokine receptor-3 (CCR3) antagonists: improving the selectivity of DPC168 by reducing central ring lipophilicity.

I. Kariv, K. Vaddi, M. Covington, 2007, Bioorganic & medicinal chemistry letters.

Selective Inhibition of Eosinophil Influx into the Lung by Small Molecule CC Chemokine Receptor 3 Antagonists in Mouse Models of Allergic Inflammation

K. McIntyre, S. Mandlekar, J. Trzăskos, 2006, Journal of Pharmacology and Experimental Therapeutics.

CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure-activity relationships.

G. Trainor, M. Covington, C. Decicco, 2002, Bioorganic & medicinal chemistry letters.

Sarcoidosis extent relates to molecular variability

R. Baughman, E. Barnathan, M. Judson, 2017, Clinical and experimental immunology.

Immune response to pneumococcus and tetanus toxoid in patients with moderate-to-severe psoriasis following long-term ustekinumab use.

K. Papp, Y. Poulin, L. Guenther, 2013, Journal of drugs in dermatology : JDD.

Selective Inhibition of Eosinophil Influx into the Lung by Small Molecule CCR3 Antagonists in Mouse Models of Allergic Inflammation

K. McIntyre, S. Mandlekar, J. Trzăskos, 2006 .

N-Arylalkylpiperidine urea derivatives as CC chemokine receptor-3 (CCR3) antagonists.

J. Trzăskos, C. Decicco, P. Carter, 2005, Bioorganic & medicinal chemistry letters.

2,4-Disubstituted piperidines as selective CC chemokine receptor 3 (CCR3) antagonists: synthesis and selectivity.

G. Trainor, M. Covington, C. Decicco, 2006, Bioorganic & medicinal chemistry letters.

Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists.

G. Trainor, M. Covington, C. Decicco, 2004, Bioorganic & medicinal chemistry letters.

Novel 1-(pyridylphenyl)-1-phenyl-2-imidazolylethanols with topical antiinflammatory activity.

S. Wright, R. Collins, R. Harris, 1992, Journal of medicinal chemistry.

Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists.

G. Trainor, M. Covington, C. Decicco, 2004, Bioorganic & medicinal chemistry letters.

From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part I: the discovery of CCR3 antagonist development candidate BMS-639623 with picomolar inhibition potency against eosinophil chemotaxis.

I. Kariv, S. Mandlekar, A. Tebben, 2008, Bioorganic & medicinal chemistry letters.

From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part II: Acyclic replacements for the (3S)-3-benzylpiperidine in a series of potent CCR3 antagonists.

A. Tebben, P. Carter, J. Duncia, 2008, Bioorganic & medicinal chemistry letters.