Kwangho Lee

发表

Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening.

Joo Yun Lee, Byung Jin Byun, Yong‐Chul Kim, 2016, Bioorganic & medicinal chemistry letters.

Rational Design, Synthesis and Evaluation of Novel C6 ‐Bicycloalkaneimidazole Containing Imidazo[1,2‐ b ]pyridazines for ASK1 Inhibition

Sunjoo Ahn, J. Jang, C. Chae, 2021, Bulletin of the Korean Chemical Society.

Novel indazole-based small compounds enhance TRAIL-induced apoptosis by inhibiting the MKK7-TIPRL interaction in hepatocellular carcinoma

Hyun-soo Cho, Nam-Soon Kim, J. Min, 2017, Oncotarget.

Two minor chalcone acetylglycosides from the roots extract of Glycyrrhiza uralensis

J. Y. Lee, S. Ryu, Jinhe Kim, 2015, Archives of pharmacal research.

BET Inhibitors as Anticancer Agents: A Patent Review.

G. Choi, Kwangho Lee, Imran Ali, 2017, Recent patents on anti-cancer drug discovery.

Development and structure-activity relationship study of SHP2 inhibitor containing 3,4,6-trihydroxy-5-oxo-5H-benzo[7]annulene.

S. B. Park, Byumseok Koh, Bohee Kim, 2019, Bioorganic & medicinal chemistry letters.

Design and synthesis of 3-(4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)-1H-quinolin-2-ones as VEGFR-2 kinase inhibitors.

H. Jung, Sun-Young Han, J. Ha, 2012, Bioorganic & medicinal chemistry letters.

First macrocyclic 3rd-generation ALK inhibitor for treatment of ALK/ROS1 cancer: Clinical and designing strategy update of lorlatinib.

Kwangho Lee, Zaman Ashraf, S. Basit, 2017, European journal of medicinal chemistry.

Novel 2,4-dianilino-5-fluoropyrimidine derivatives possessing ALK inhibitory activities

Chi-Hoon Park, H. Jung, C. Yun, 2014, Archives of pharmacal research.

ALK inhibitors of bis-ortho-alkoxy-para-piperazinesubstituted-pyrimidines and -triazines for cancer treatment

Chi-Hoon Park, C. Chae, Heung Kyoung Lee, 2014, Archives of pharmacal research.

Novel bis-ortho-alkoxy-para-piperazinesubstituted-2,4-dianilinopyrimidines (KRCA-0008) as potent and selective ALK inhibitors for anticancer treatment.

Chi-Hoon Park, H. Jung, C. Yun, 2013, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationship of aminopyridines with substituted benzoxazoles as c-Met kinase inhibitors.

Chi-Hoon Park, H. Jung, Sang-Un Choi, 2012, Bioorganic & medicinal chemistry letters.

Two Novel Guaiane Sesquiterpenes from the Whole Plant of Youngia japonica

J. Y. Lee, S. Ryu, M. R. Kim, 2015 .

Rotational Variance-Based Data Augmentation in 3D Graph Convolutional Network.

I. Choi, E. Lee, C. Chae, 2021, Chemistry, an Asian journal.

ALK inhibitors of bis-ortho-alkoxy-para-piperazinesubstituted-pyrimidines and -triazines for cancer treatment

Chi-Hoon Park, C. Chae, Heung Kyoung Lee, 2014, Archives of Pharmacal Research.

Development of potent ALK inhibitor and its molecular inhibitory mechanism against NSCLC harboring EML4-ALK proteins.

H. Jeong, Chi-Hoon Park, H. Jung, 2015, Biochemical and biophysical research communications.

The positive correlation of TIPRL with LC3 and CD133 contributes to cancer aggressiveness: potential biomarkers for early liver cancer

Nam-Soon Kim, S. Jeon, Ji-Yong Yoon, 2019, Scientific Reports.

Novel Allosteric Glutaminase 1 Inhibitors with Macrocyclic Structure Activity Relationship Analysis.

J. Jang, Rajath Cyriac, G. Choi, 2022, Bioorganic & medicinal chemistry letters.

Design, Synthesis, and Evaluation of 2‐Anilino‐4‐(3,5‐dicarboxamidespiperidine)‐pyrimidines as Anaplastic Lymphoma Kinase Inhibitors

Chi-Hoon Park, C. Yun, C. Chae, 2015 .

Identification of Pyrrole[3,4-c]pyrazoles as Potent Tropomyosin Receptor Kinase A (TrkA) Inhibitors

Byung Jin Byun, Sang-Un Choi, Y. Son, 2016 .

Discovery of novel [1,2,4]triazolo[4,3-a]quinoxaline aminophenyl derivatives as BET inhibitors for cancer treatment.

Gildon Choi, Kwangho Lee, Imran Ali, 2017, Bioorganic & medicinal chemistry letters.

Investigation of benzimidazole anthelmintics as oral anticancer agents

J. Jang, Byumseok Koh, Kwangho Lee, 2022, Bulletin of the Korean Chemical Society.

Allosteric Inhibitor TREA-0236 Containing Non-hydrolysable Quinazoline-4-one for EGFR T790M/C797S Mutants Inhibition

B. Cho, C. Chae, G. Choi, 2018, Bulletin of the Korean Chemical Society.

Novel 2,4-dianilino-5-fluoropyrimidine derivatives possessing ALK inhibitory activities

Chi-Hoon Park, H. Jung, C. Yun, 2013, Archives of Pharmacal Research.

Identification of TRD‐35 as Potent and Selective DRAK2 Inhibitor

C. Chae, G. Choi, Myoung Eun Jung, 2020 .

Discovery of TRD‐93 as a novel DRAK2 inhibitor

C. Chae, G. Choi, Myoung Eun Jung, 2023, Bulletin of the Korean Chemical Society.

Structure–Activity Relationship Study of 2,4‐Dianilinopyrimidine Containing Methanesulfonamide (TRE‐069) as Potent and Selective Epidermal Growth Factor Receptor T790M/C797S Mutant Inhibitor for Anticancer Treatment

B. Cho, C. Chae, G. Choi, 2017 .

Identification of TRE‐130 as Reversible Inhibitor of Pan‐EGFR Mutants while Sparing EGFR Wild‐Type Activity

B. Cho, Byungho Lim, C. Chae, 2019, Bulletin of the Korean Chemical Society.

3D-QSAR Studies on Chemical Features of 3-(benzo[d]oxazol-2-yl)pyridine-2-amines in the External Region of c-Met Active Site

Joo Yun Lee, C. Chae, Kwangho Lee, 2013 .

Design and synthesis of 3-(4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)-1H-quinolin-2-ones as VEGFR-2 kinase inhibitors.

H. Jung, Sun-Young Han, J. Ha, 2012, Bioorganic & medicinal chemistry letters.

Can We Prevent Resistance to Osimertinib? Combination or Sequential.

Min Hwan Kim, S. Lim, B. Cho, 2018, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.