Hui-Fang Liu

发表

Human neuronal uncoupling proteins 4 and 5 (UCP4 and UCP5): structural properties, regulation, and physiological role in protection against oxidative stress and mitochondrial dysfunction

K. Chan, S. Ho, P. Ho, 2012, Brain and behavior.

Mitochondrial UCP4 attenuates MPP+ - and dopamine-induced oxidative stress, mitochondrial depolarization, and ATP deficiency in neurons and is interlinked with UCP2 expression.

K. Chan, S. Ho, P. Ho, 2009, Free radical biology & medicine.

Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson’s disease

S. Ho, P. Ho, Lingfei Li, 2017, Scientific Reports.

Title Combined LRRK 2 mutation , aging and chronic low dose oralrotenone as a model of Parkinson ’ s disease

S. Pang, D. Ramsden, Hui-Fang Liu, 2017 .

Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson’s disease

S. Ho, P. Ho, Lingfei Li, 2017, Scientific Reports.

Title Uncoupling protein-4 ( UCP 4 ) increases ATP supply byinteracting with mitochondrial complex II in neuroblastoma cells

K. Chan, S. Ho, P. Ho, 2012 .

Uncoupling Protein-4 (UCP4) Increases ATP Supply by Interacting with Mitochondrial Complex II in Neuroblastoma Cells

K. Chan, S. Ho, P. Ho, 2012, PloS one.

Title Mitochondrial uncoupling protein-2 ( UCP 2 ) mediates leptinprotection against MPP + toxicity in neuronal cells

K. Chan, S. Ho, P. Ho, 2010 .

Mitochondrial Uncoupling Protein-2 (UCP2) Mediates Leptin Protection Against MPP+ Toxicity in Neuronal Cells

K. Chan, S. Ho, P. Ho, 2009, Neurotoxicity Research.

Transcriptional regulation of UCP4 by NF-kappaB and its role in mediating protection against MPP+ toxicity.

K. Chan, S. Ho, P. Ho, 2010, Free radical biology & medicine.

Transcriptional Regulation of the Synaptic Vesicle Protein Synaptogyrin-3 (SYNGR3) Gene: The Effects of NURR1 on Its Expression

S. Ho, Lingfei Li, S. Pang, 2022, International journal of molecular sciences.

LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity

S. Ho, Zhongjun Zhou, P. Ho, 2014, Annals of clinical and translational neurology.

UCP4 is a target effector of the NF-κB c-Rel prosurvival pathway against oxidative stress.

K. Chan, S. Ho, P. Ho, 2012, Free radical biology & medicine.

Long-term inhibition of mutant LRRK2 hyper-kinase activity reduced mouse brain α-synuclein oligomers without adverse effects

J. Mak, S. Ho, S. Yung, 2022, NPJ Parkinson's disease.

Assessment of Cellular Estrogenic Activity Based on Estrogen Receptor-Mediated Reduction of Soluble-Form Catechol-O-Methyltransferase (COMT) Expression in an ELISA-Based System

S. Ho, P. Ho, Song Lu, 2013, PloS one.

Mitochondrial UCP5 is neuroprotective by preserving mitochondrial membrane potential, ATP levels, and reducing oxidative stress in MPP+ and dopamine toxicity.

K. Chan, S. Ho, P. Ho, 2010, Free radical biology & medicine.

Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2R1441G mice

S. Ho, P. Ho, S. Pang, 2020, Autophagy.

Long-term inhibition of mutant LRRK2 hyper-kinase activity reduced mouse brain α-synuclein oligomers without adverse effects

S. Ho, S. Yung, S. Pang, 2022, npj Parkinson's Disease.

Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA)

S. Ho, P. Ho, Lingfei Li, 2019, Autophagy.

The interplay of aging, genetics and environmental factors in the pathogenesis of Parkinson’s disease

S. Ho, P. Ho, Lingfei Li, 2019, Translational Neurodegeneration.

Identification of MHC I class genes in two Platyrrhini species

Hui-Fang Liu, Aixue Li, L. Zeng, 2015, American journal of primatology.

LRRK2 mutant knock-in mouse models: therapeutic relevance in Parkinson's disease

S. Ho, S. Pang, D. Ramsden, 2022, Translational neurodegeneration.

LRRK2, GBA and their interaction in the regulation of autophagy: implications on therapeutics in Parkinson's disease

S. Ho, S. Pang, D. Ramsden, 2022, Translational neurodegeneration.

Structure-based prediction of post-translational modification cross-talk within proteins using complementary residue- and residue pair-based features

Rong Liu, Hui-Fang Liu, Rong Liu, 2020, Briefings Bioinform..

Global RNA editing identification and characterization during human pluripotent-to-cardiomyocyte differentiation

Jian Liu, Hui-Fang Liu, Yan Lin, 2021, Molecular therapy. Nucleic acids.

Title Mitochondrial neuronal uncoupling proteins : a target forpotential disease-modification in Parkinson ' s disease

K. Chan, S. Ho, D. Ramsden, 2012 .

Mitochondrial neuronal uncoupling proteins: a target for potential disease-modification in Parkinson's disease

K. Chan, S. Ho, D. Ramsden, 2012, Translational Neurodegeneration.

Systematic comparison and prediction of the effects of missense mutations on protein-DNA and protein-RNA interactions

Rong Liu, Hui-Fang Liu, Yaoxin Jiang, 2021, PLoS Comput. Biol..

In vivo overexpression of synaptogyrin‐3 promotes striatal synaptic dopamine uptake in LRRK2R1441G mutant mouse model of Parkinson's disease

S. Ho, Lingfei Li, S. Pang, 2023, Brain and behavior.

Integrating co‐evolutionary signals and other properties of residue pairs to distinguish biological interfaces from crystal contacts

Jia Wang, Rong Liu, Jun Sun, 2018, Protein science : a publication of the Protein Society.

Mitochondrial Uncoupling Protein-2 (UCP2) Mediates Leptin Protection Against MPP+ Toxicity in Neuronal Cells

K. Chan, S. Ho, P. Ho, 2009, Neurotoxicity Research.