Hélène Morin

发表

Computer-aided drug discovery of Myc-Max inhibitors as potential therapeutics for prostate cancer.

Lavinia A. Carabet, Fariba Ghaidi, I. Mills, 2018, European journal of medicinal chemistry.

Cheminformatics Driven Development of Novel Therapies for Drug Resistant Prostate Cancer

P. Rennie, F. Ban, A. Cherkasov, 2018, Molecular informatics.

Dual-Inhibitors of N-Myc and AURKA as Potential Therapy for Neuroendocrine Prostate Cancer

F. Ban, Kriti Singh, A. Cherkasov, 2020, International journal of molecular sciences.

Selectively targeting the dimerization interface of human androgen receptor with small-molecules to treat castration-resistant prostate cancer.

P. Rennie, J. Peacock, F. Ban, 2018, Cancer letters.

Evaluation of Darolutamide (ODM201) Efficiency on Androgen Receptor Mutants Reported to Date in Prostate Cancer Patients

M. Gleave, Oliver Snow, A. Cherkasov, 2021, Cancers.

Structure-Based Study to Overcome Cross-Reactivity of Novel Androgen Receptor Inhibitors

P. Rennie, F. Ban, Kriti Singh, 2015, Cells.

Development of an Androgen Receptor Inhibitor Targeting the N-Terminal Domain of Androgen Receptor for Treatment of Castration Resistant Prostate Cancer

Ayse Derya Cavga, M. Gleave, P. Rennie, 2021, Cancers.

Small molecule-induced degradation of the full length and V7 truncated variant forms of human androgen receptor.

P. Rennie, F. Ban, A. Cherkasov, 2018, European journal of medicinal chemistry.

Development of VPC-70619, a Small-Molecule N-Myc Inhibitor as a Potential Therapy for Neuroendocrine Prostate Cancer

F. Ban, Kriti Singh, A. Cherkasov, 2022, International journal of molecular sciences.

The Nuclear Receptor Superfamily

P. Rennie, N. Lallous, Hélène Morin, 2016, Methods in Molecular Biology.

Computer-Aided Discovery of Small Molecules Targeting the RNA Splicing Activity of hnRNP A1 in Castration-Resistant Prostate Cancer

Lavinia A. Carabet, P. Rennie, A. Cherkasov, 2019, Molecules.

Development of 2-(5,6,7-Trifluoro-1H-Indol-3-yl)-quinoline-5-carboxamide as a Potent, Selective, and Orally Available Inhibitor of Human Androgen Receptor Targeting Its Binding Function-3 for the Treatment of Castration-Resistant Prostate Cancer.

Ayse Derya Cavga, M. Gleave, R. Young, 2021, Journal of medicinal chemistry.

Targeting Binding Function-3 of the Androgen Receptor Blocks Its Co-Chaperone Interactions, Nuclear Translocation, and Activation

R. Young, P. Rennie, Kriti Singh, 2016, Molecular Cancer Therapeutics.

Drug-Discovery Pipeline for Novel Inhibitors of the Androgen Receptor.

P. Rennie, A. Cherkasov, Kush Dalal, 2016, Methods in molecular biology.

Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression

Jennifer M. Bui, L. Fazli, P. Rennie, 2022, Nucleic acids research.