J. Ferland

发表

Olefin ring-closing metathesis as a powerful tool in drug discovery and development – potent macrocyclic inhibitors of the hepatitis C virus NS3 protease

M. Poirier, Y. Tsantrizos, Xudong Wei, 2006 .

Potent inhibitors of the hepatitis C virus NS3 protease: design and synthesis of macrocyclic substrate-based beta-strand mimics.

C. Brochu, M. Poirier, Y. Tsantrizos, 2004, The Journal of organic chemistry.

Synthetic new cardenolides

Y. Lefebvre, R. Deghenghi, J. Ferland, 1966 .

Binding mode determination of benzimidazole inhibitors of the hepatitis C virus RNA polymerase by a structure and dynamics strategy.

S. LaPlante, J. Gillard, A. Jakalian, 2004, Angewandte Chemie.

Synthesis of derivatives of isoindole and of pyrazino[2,1-a]isoindole

J. Ferland, C. Demerson, L. Humber, 1985 .

Structure-activity study on a novel series of macrocyclic inhibitors of the hepatitis C virus NS3 protease leading to the discovery of BILN 2061.

Martin Poirier, M. Garneau, D. Lamarre, 2004, Journal of medicinal chemistry.

Synthesis of BILN 2061, an HCV NS3 protease inhibitor with proven antiviral effect in humans.

Martin Poirier, C. Brochu, M. Poirier, 2004, Organic letters.

STEREOCHEMICAL STUDIES: VI. REACTIONS OF 3β-HYDROXY-4-OXA-5α-ESTRANE AND 3α,17β-DIHYDROXY-4-OXA-5α-ESTRANE

J. T. Edward, J. Ferland, 1966 .

STEREOCHEMICAL STUDIES: VIII. SYNTHESIS OF cis-1-OXA-10-METHYLDECAL-2-ONE

J. T. Edward, J. Ferland, 1966 .

RCM of tripeptide dienes containing a chiral vinylcyclopropane moiety: impact of different Ru-based catalysts on the stereochemical integrity of the macrocyclic products.

S. LaPlante, M. Poirier, Y. Tsantrizos, 2005, The Journal of organic chemistry.

A novel colour reaction of some Euphorbia and Oxyanthus species

J. T. Edward, J. Ferland, R. D. Gibbs, 1967 .

Peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase with improved in vivo antiviral activity.

M. Garneau, C. Yoakim, N. Moss, 1996, Journal of medicinal chemistry.

A new solid phase strategy for the synthesis of mammalian glucagon

J. Gauthier, S. Rakhit, J. Ferland, 1991 .

Peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase: a new class of antiviral agents.

N. Moss, P. Beaulieu, J. Gauthier, 1995, Journal of medicinal chemistry.

Ligands for the tyrosine kinase p56lck SH2 domain: discovery of potent dipeptide derivatives with monocharged, nonhydrolyzable phosphate replacements.

J. Proudfoot, L. Tong, E. Hickey, 1999, Journal of medicinal chemistry.

Synthetic Cardenolides and Related Products. III. Isocardenolides

J. Ferland, 1974 .

Inhibition of herpes simplex virus type 1 ribonucleotide reductase by substituted tetrapeptide derivatives.

J. DiMaio, N. Moss, P. Beaulieu, 1993, Journal of medicinal chemistry.

An Enantioselective Synthesis of Cyclopentyl-L-Aspartic Acid Amenable to Large Scale

N. Moss, I. Guse, L. Plamondon, 1997 .

Herpes simplex virus ribonucleotide reductase subunit association inhibitors: the effect and conformation of beta-alkylated aspartic acid derivatives.

N. Moss, R. Déziel, T. Pitner, 1994, Bioorganic & medicinal chemistry.