E. Ferrari

发表

Hepatitis C Virus NS5B Polymerase Exhibits Distinct Nucleotide Requirements for Initiation and Elongation*

H. Huang, R. Palermo, E. Ferrari, 2008, Journal of Biological Chemistry.

I. Novel HCV NS5B polymerase inhibitors: discovery of indole 2-carboxylic acids with C3-heterocycles.

B. Feld, R. Palermo, J. Duca, 2011, Bioorganic & medicinal chemistry letters.

Mutational Analysis of Bovine Viral Diarrhea Virus RNA-Dependent RNA Polymerase

C. Kao, A. Uss, E. Ferrari, 1999, Journal of Virology.

A novel hepatitis C virus NS5B polymerase assay of de novo initiated RNA synthesis directed from a heteropolymeric RNA template.

E. Ferrari, Hsueh-Cheng Huang, Hsueh‐Cheng Huang, 2013, Methods in molecular biology.

Optimization of potency and pharmacokinetics of tricyclic indole derived inhibitors of HCV NS5B polymerase. Identification of ester prodrugs with improved oral pharmacokinetics.

J. Duca, F. G. Njoroge, S. Agrawal, 2014, Bioorganic & medicinal chemistry.

Amide derivatives of partricin A with potent antifungal activity

E. Ferrari, A. Bonabello, T. Bruzzese, 1996 .

SCH 43478 and analogs: in vitro activity and in vivo efficacy of novel agents for herpesvirus type 2.

A. Kwong, J. O'Connell, E. Rozhon, 1997, Antiviral Research.

Discovery of an irreversible HCV NS5B polymerase inhibitor.

J. Gesell, J. Duca, F. G. Njoroge, 2013, Bioorganic & medicinal chemistry letters.

Effects of genotypic variations on hepatitis C virus nonstructural protein 5B structure and activity

Z. Hong, W. Zhong, C. Lesburg, 2003 .

Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site

Charles A. Lesburg, P. Weber, Z. Hong, 1999, Nature Structural Biology.

Template/Primer Requirements and Single Nucleotide Incorporation by Hepatitis C Virus Nonstructural Protein 5B Polymerase

C. Cameron, Z. Hong, W. Zhong, 2000, Journal of Virology.

Characterization of Soluble Hepatitis C Virus RNA-Dependent RNA Polymerase Expressed in Escherichia coli

Z. Hong, B. Baroudy, E. Ferrari, 1999, Journal of Virology.

Inhibitors of hepatitis C virus polymerase: synthesis and characterization of novel 2-oxy-6-fluoro-N-((S)-1-hydroxy-3-phenylpropan-2-yl)-benzamides.

Sony Agrawal, Charles A. Lesburg, Gerald W. Shipps, 2010, Bioorganic & medicinal chemistry letters.

Enzymatic characterization of hepatitis C virus NS3/4A complexes expressed in mammalian cells by using the herpes simplex virus amplicon system

G. Seelig, A. Kwong, Z. Hong, 1996, Journal of virology.

De Novo Initiation of RNA Synthesis by Hepatitis C Virus Nonstructural Protein 5B Polymerase

Z. Hong, W. Zhong, J. Lau, 2000, Journal of Virology.

Antipicornavirus activity of SCH 47802 and analogs: in vitro and in vivo studies.

J. O'Connell, E. Rozhon, A. Skelton, 1996, Antiviral research.

Discovery of novel tricyclic indole derived inhibitors of HCV NS5B RNA dependent RNA polymerase.

J. Duca, F. G. Njoroge, S. Agrawal, 2013, Bioorganic & medicinal chemistry.

Concise syntheses and HCV NS5B polymerase inhibition of (2'R)-3 and (2'S)-2'-ethynyluridine-10 and related nucleosides.

M. Senior, A. Malikzay, P. Tawa, 2017, Bioorganic & Medicinal Chemistry Letters.

In Vitro Antiviral Profile of Ruzasvir, a Potent and Pangenotype Inhibitor of Hepatitis C Virus NS5A

E. Asante-Appiah, F. Lahser, S. Agrawal, 2018, Antimicrobial Agents and Chemotherapy.

SCH 48973: a potent, broad-spectrum, antienterovirus compound

J. O'Connell, J. Modlin, E. Rozhon, 1997, Antimicrobial agents and chemotherapy.

Combination therapy with the farnesyl protein transferase inhibitor SCH66336 and SCH58500 (p53 adenovirus) in preclinical cancer models.

W. R. Bishop, Meilin Liu, L. Nielsen, 1999, Cancer research.

Hepatitis C Virus NS5B Polymerase Exhibits Distinct Nucleotide Requirements for Initiation and Elongation*

R. Palermo, E. Ferrari, Zhiqing He, 2008, Journal of Biological Chemistry.