Allison M. Keeler

发表

Cell and gene therapy for genetic diseases: inherited disorders affecting the lung and those mimicking sudden infant death syndrome.

T. Flotte, Allison M. Keeler, A. Keeler, 2012, Human gene therapy.

Evaluating Readministration of Adeno-Associated Virus for Gene Therapy.

Allison M. Keeler, Motahareh Arjomandnejad, A. Keeler, 2022, Human gene therapy.

Airway smooth muscle dysfunction in Pompe (Gaa-/- ) mice.

B. Byrne, D. Fuller, M. ElMallah, 2017, American journal of physiology. Lung cellular and molecular physiology.

CAR T-Cell Therapy: Progress and Prospects.

T. Flotte, Allison M. Keeler, Olivia Wilkins, 2017, Human gene therapy methods.

Gene Therapy for Very Long Chain Acyl-coA Dehydrogenase Deficiency Using Adeno-Associated Virus Vectors: A Dissertation

Allison M. Keeler, A. Keeler, 2012 .

Long-term Correction of Very Long-chain Acyl-CoA Dehydrogenase Deficiency in Mice Using AAV9 Gene Therapy

T. Conlon, T. Flotte, S. Shaffer, 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

First-in-human AAV Gene Therapy for Tay-Sachs Disease

Douglas R Martin, T. Flotte, F. Eichler, 2021 .

Bridging from Intramuscular to Limb Perfusion Delivery of rAAV: Optimization in a Non-human Primate Study

T. Flotte, C. Mueller, L. Chicoine, 2019, Molecular therapy. Methods & clinical development.

Intralingual and Intrapleural AAV Gene Therapy Prolongs Survival in a SOD1 ALS Mouse Model

Robert H. Brown, C. Mueller, M. ElMallah, 2019, Molecular therapy. Methods & clinical development.

Modulation of exaggerated-IgE allergic responses by gene transfer-mediated antagonism of IL-13 and IL-17e.

T. Flotte, C. Mueller, Q. Tang, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Systemic Delivery of AAVB1-GAA Clears Glycogen and Prolongs Survival in a Mouse Model of Pompe Disease.

B. Byrne, Angela L McCall, M. ElMallah, 2019, Human gene therapy.

Two-Plasmid Packaging System for Recombinant Adeno-Associated Virus

T. Flotte, G. Gao, Q. Su, 2020, BioResearch open access.

AAV gene therapy for Tay-Sachs disease

Douglas R Martin, T. Flotte, F. Eichler, 2022, Nature Medicine.

Lack of cystic fibrosis transmembrane conductance regulator in CD3+ lymphocytes leads to aberrant cytokine secretion and hyperinflammatory adaptive immune responses.

M. Drumm, T. Flotte, C. Hodges, 2011, American journal of respiratory cell and molecular biology.

Restrictive Lung Disease in the Cu/Zn Superoxide-Dismutase 1 G93A Amyotrophic Lateral Sclerosis Mouse Model.

T. Flotte, M. ElMallah, M. Sena-Esteves, 2017, American journal of respiratory cell and molecular biology.

Rational Use of Immunosuppressive Corticosteroids in Liver-Directed Adeno-Associated Virus Gene Therapy Studies.

Allison M. Keeler, I. Dasgupta, A. Keeler, 2022, Human gene therapy.

CAR-T Regulatory (CAR-Treg) Cells: Engineering and Applications

Allison M. Keeler, Motahareh Arjomandnejad, Acadia L Kopec, 2022, Biomedicines.

Recombinant Adeno-Associated Virus Gene Therapy in Light of Luxturna (and Zolgensma and Glybera): Where Are We, and How Did We Get Here?

Terence R Flotte, T. Flotte, Allison M Keeler, 2019, Annual review of virology.

Novel Combinatorial MicroRNA-Binding Sites in AAV Vectors Synergistically Diminish Antigen Presentation and Transgene Immunity for Efficient and Stable Transduction

Katelyn E. Sylvia, G. Gao, Q. Su, 2021, Frontiers in Immunology.

Pollen-derived RNAs Are Found in the Human Circulation

D. Levy, M. Gerstein, J. Rozowsky, 2019, iScience.

Widespread Central Nervous System Gene Transfer and Silencing After Systemic Delivery of Novel AAV-AS Vector.

Sourav R. Choudhury, M. Sena-Esteves, G. Gao, 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

Modulating immune responses to AAV by expanded polyclonal T-regs and capsid specific chimeric antigen receptor T-regulatory cells

T. Flotte, Katelyn E. Sylvia, G. Gao, 2021, Molecular Therapy. Methods & Clinical Development.

Immunogenicity of Recombinant Adeno-Associated Virus (AAV) Vectors for Gene Transfer

T. Flotte, Allison M. Keeler, Motahareh Arjomandnejad, 2023, BioDrugs.

Systemic AAV9 gene transfer in adult GM1 gangliosidosis mice reduces lysosomal storage in CNS and extends lifespan.

S. Shaffer, M. Sena-Esteves, G. Gao, 2015, Human molecular genetics.

CRISPR/Cas-Dependent and Nuclease-Free In Vivo Therapeutic Gene Editing

T. Flotte, Allison M. Keeler, I. Dasgupta, 2021, Human gene therapy.

AAV9 gene replacement therapy for respiratory insufficiency in very‐long chain acyl‐CoA dehydrogenase deficiency

T. Flotte, M. ElMallah, Allison M. Keeler, 2019, Journal of inherited metabolic disease.

Cellular Analysis of Silencing the Huntington's Disease Gene Using AAV9 Mediated Delivery of Artificial Micro RNA into the Striatum of Q140/Q140 Mice.

Eric W. Danielson, M. Sena-Esteves, N. Aronin, 2016, Journal of Huntington's disease.

Immune Responses to Adeno-Associated Virus-Mediated CRISPR Therapy.

Allison M. Keeler, A. Keeler, 2021, Human gene therapy.

Limb Perfusion Delivery of a rAAV1 Alpha-1 Antitrypsin Vector in Non-Human Primates Is Safe but Insufficient for Therapy

Allison M. Keeler, Meghan Blackwood, A. Gruntman, 2024, Genes.

Biodistribution and safety of a single rAAV3B-AAT vector for silencing and replacement of alpha-1 antitrypsin in Cynomolgus macaques

Allison M. Keeler, Meghan Blackwood, A. Gruntman, 2024, Molecular therapy. Methods & clinical development.