K. Landgraf

发表

Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domain.

J. Falke, K. Landgraf, Carissa Pilling, 2008, Biochemistry.

Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform

L. Weinberger, Steven R. Williams, W. Greene, 2019, Cell.

Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity

S. Maier, Y. Zhang, L. Watkins, 2010, Neuroscience.

Evidence that tricyclic small molecules may possess Toll-like receptor and MD-2 activity

S. Maier, L. Watkins, S. Phipps, 2010 .

The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3).

J. Falke, K. Landgraf, Carissa Pilling, 2011, Biochemistry.

Evidence that opioids may have toll-like receptor 4 and MD-2 effects

S. Maier, L. Leinwand, L. Watkins, 2010, Brain, Behavior, and Immunity.

Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity.

J. Falke, John H. Evans, K. Landgraf, 2007, Biochemistry.

Single-Molecule Studies Reveal a Hidden Key Step in the Activation Mechanism of Membrane-Bound Protein Kinase C-α

G. Voth, J. Falke, Jianing Li, 2014, Biochemistry.

convertibleCAR-T cells provide a modular universal system for dose control of activity, flexible targeting, and versatile maintenance of CAR-cells

Kole T. Roybal, Steven R. Williams, Stephen Lok, 2019 .

convertibleCARs: A chimeric antigen receptor system for flexible control of activity and antigen targeting

Kole T. Roybal, Steven R. Williams, Stephen Lok, 2019, Communications Biology.

Membrane docking geometry and target lipid stoichiometry of membrane-bound PKCα C2 domain: a combined molecular dynamics and experimental study.

G. Voth, J. Falke, Chun-Liang Lai, 2010, Journal of molecular biology.

Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation study.

J. Falke, K. Landgraf, Nathan J Malmberg, 2008, Biochemistry.

An allosteric anti-hepsin antibody derived from a constrained phage display library.

Yingnan Zhang, D. Kirchhofer, R. Ganesan, 2012, Protein engineering, design & selection : PEDS.

An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides.

C. Eigenbrot, R. Lazarus, C. Quan, 2014, Nature chemical biology.

Allosteric Peptide Activators of Pro-Hepatocyte Growth Factor Stimulate Met Signaling

D. Kirchhofer, R. Lazarus, Judy C. Young, 2010, The Journal of Biological Chemistry.

Membrane Docking Geometry of GRP1 PH Domain Bound to a Target Lipid Bilayer: An EPR Site-Directed Spin-Labeling and Relaxation Study

J. Falke, B. Ziemba, K. Landgraf, 2012, PloS one.

Evidence that opioids may have toll-like receptor 4 and MD-2 effects

S. Maier, L. Leinwand, L. Watkins, 2010, Brain, Behavior, and Immunity.