S. Pathania

发表

Genetically defined syngeneic mouse models of ovarian cancer as tools for the discovery of combination immunotherapy.

R. Weinberg, G. Bell, H. Horn, 2020, Cancer discovery.

The tumor mutational landscape of BRCA2-deficient primary and metastatic prostate cancer

T. Rebbeck, S. Baichoo, K. Kensler, 2022, npj Precision Oncology.

A general model for site-specific recombination by the integrase family recombinases.

M. Jayaram, S. Pathania, Y. Voziyanov, 1999, Nucleic acids research.

Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage.

J. Parvin, G. Shapiro, A. D’Andrea, 2009, Molecular cell.

Mixing Mutation Location With Carcinogen Exposure: A Recipe for Tissue Specificity in BRCA2-Associated Cancers?

J. Garber, S. Pathania, 2018, Journal of the National Cancer Institute.

Overexpression of BLM promotes DNA damage and increased sensitivity to platinum salts in triple-negative breast and serous ovarian cancers

Z. Szallasi, M. Dreze, A. Richardson, 2018, Annals of oncology : official journal of the European Society for Medical Oncology.

RPA, RFWD3 and BRCA2 at stalled forks: a balancing act

S. Pathania, Haohui Duan, 2020, Molecular & cellular oncology.

A unique right end–enhancer complex precedes synapsis of Mu ends: the enhancer is sequestered within the transpososome throughout transposition

M. Jayaram, R. Harshey, S. Pathania, 2003, The EMBO journal.

The Mu Transposase Interwraps Distant DNA Sites within a Functional Transpososome in the Absence of DNA Supercoiling*

M. Jayaram, R. Harshey, S. Pathania, 2005, Journal of Biological Chemistry.

Path of DNA within Mu transpososomes: order, dynamics and topology of Mu end-enhancer interactions

S. Pathania, 2002 .

Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma

Z. Szallasi, I. Csabai, G. Klus, 2023, bioRxiv.

MAPK Pathway Suppression Unmasks Latent DNA Repair Defects and Confers a Chemical Synthetic Vulnerability in BRAF-, NRAS-, and NF1-Mutant Melanomas.

Levi A Garraway, Keith T Flaherty, Thomas De Raedt, 2019, Cancer discovery.

Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes.

R. Greenberg, B. Sobhian, D. Livingston, 2006, Genes & development.

BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model

Z. Szallasi, A. Giobbie-Hurder, A. Bass, 2021, Proceedings of the National Academy of Sciences.

Increased frequency of CHD1 deletions in prostate cancers of African American men is associated with distinct homologous recombination deficiency associated DNA aberration profiles

Z. Szallasi, I. Csabai, G. Klus, 2021, medRxiv.

BRCA1 haploinsufficiency for replication stress suppression in primary cells

A. Richardson, K. Polyak, D. Livingston, 2014, Nature Communications.

BRCA 1 / BARD 1-containing complexes Multifactorial contributions to an acute DNA damage response

R. Greenberg, B. Sobhian, D. Livingston, 2005 .

BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells.

A. Giobbie-Hurder, K. Polyak, R. Gelman, 2016, Molecular cell.

BRCA1 is required for postreplication repair after UV-induced DNA damage.

D. Livingston, G. Adelmant, J. Marto, 2011, Molecular cell.

BRCA1 Recruitment to Transcriptional Pause Sites Is Required for R-Loop-Driven DNA Damage Repair

Manolis Kellis, G. Parmigiani, D. Livingston, 2015, Molecular cell.

E3 ligase RFWD3 is a novel modulator of stalled fork stability in BRCA2-deficient cells

Z. Szallasi, J. Garber, N. Birkbak, 2020, The Journal of cell biology.

Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cycle

D. Livingston, C. Kanellopoulou, S. Pathania, 2013, Genes & development.

Using the CRISPR/Cas9 System to Derive an Isogenic BRCA1 Mutant (187delAG) Strain From a Wild Type BRCA1 Mammary Epithelial Strain

S. Pathania, 2016 .

BRCA 1 Recruitment to Transcriptional Pause Sites Is Required for R-Loop-Driven DNA Damage Repair

Manolis Kellis, G. Parmigiani, D. Livingston, 2022 .

Path of DNA within the Mu Transpososome Transposase Interactions Bridging Two Mu Ends and the Enhancer Trap Five DNA Supercoils

M. Jayaram, R. Harshey, S. Pathania, 2002, Cell.

Symmetric DNA sites are functionally asymmetric within Flp and Cre site-specific DNA recombination synapses.

A. Vologodskii, M. Jayaram, R. Harshey, 2002, Journal of molecular biology.

Flp Ribonuclease Activities

Y. Ahn, M. Jayaram, C. Xu, 1998, The Journal of Biological Chemistry.

Structural alterations and conformational dynamics in Holliday junctions induced by binding of a site-specific recombinase.

M. Jayaram, J. Lee, S. Pathania, 1998, Molecular cell.

True reversal of Mu integration

R. Harshey, S. Pathania, T. K. Au, 2004, The EMBO journal.

Fibroblast–tumor cell signaling limits HER2 kinase therapy response via activation of MTOR and antiapoptotic pathways

G. Mills, P. Sorger, Jia-Ren Lin, 2020, Proceedings of the National Academy of Sciences.

The RNA-binding protein Adad1 is necessary for germ cell maintenance and meiosis in zebrafish

K. Islam, Anuoluwapo Ajao, S. Pathania, 2023, PLoS genetics.

Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer

Pamoda M Galhenage, S. Pathania, Ferenc Reinhardt, 2023, Cell reports.