D. Wakita

发表

Effects of AhR ligands on the production of immunoglobulins in purified mouse B cells.

Takayuki Yoshida, K. Katsuya, T. Oka, 2012, Biomedical research.

Quercetin Inhibits Inflammasome Activation by Interfering with ASC Oligomerization and Prevents Interleukin-1 Mediated Mouse Vasculitis

T. Crother, M. Arditi, K. Shimada, 2017, Scientific Reports.

3‐Methylcholanthrene‐induced transforming growth factor‐β‐producing carcinomas, but not sarcomas, are refractory to regulatory T cell‐depletion therapy

K. Matsushima, K. Chamoto, D. Wakita, 2010, Cancer science.

CD8+ T Cells Contribute to the Development of Coronary Arteritis in the Lactobacillus casei Cell Wall Extract–Induced Murine Model of Kawasaki Disease

M. Fishbein, N. Chiba, J. Dagvadorj, 2017, Arthritis & rheumatology.

IL-1 Signaling Is Critically Required in Stromal Cells in Kawasaki Disease Vasculitis Mouse Model: Role of Both IL-1&agr; and IL-1&bgr;

M. Fishbein, J. Dagvadorj, Shuang Chen, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes.

H. Ikeda, H. Miyoshi, Y. Oka, 2005, Blood.

Expression of the MAGE-A 4 and NY-ESO-1 cancer-testis antigens and T cell infiltration in non-small cell lung carcinoma and their prognostic significance

H. Ikeda, S. Kondo, M. Miyamoto, 2022 .

Extracts of Larix Leptolepis effectively augments the generation of tumor antigen-specific cytotoxic T lymphocytes via activation of dendritic cells in TLR-2 and TLR-4-dependent manner.

H. Tabata, S. Koizumi, D. Wakita, 2012, Cellular immunology.

Combination immunotherapy with radiation and CpG‐based tumor vaccination for the eradication of radio‐ and immuno‐resistant lung carcinoma cells

H. Shirato, Y. Togashi, T. Omatsu, 2009, Cancer science.

Identification of novel helper epitopes of MAGE-A4 tumour antigen: useful tool for the propagation of Th1 cells

Y. Togashi, K. Chamoto, D. Wakita, 2009, British Journal of Cancer.

Essential role of Toll-like receptors for dendritic cell and NK1.1(+) cell-dependent activation of type 1 immunity by Lactobacillus pentosus strain S-PT84.

Tomomi Sato, Y. Togashi, T. Izumo, 2008, Immunology letters.

An indispensable role of type-1 IFNs for inducing CTL-mediated complete eradication of established tumor tissue by CpG-liposome co-encapsulated with model tumor antigen.

Yue Zhang, H. Ikeda, T. Iguchi, 2006, International immunology.

An essential role of antigen-presenting cell/T-helper type 1 cell-cell interactions in draining lymph node during complete eradication of class II-negative tumor tissue by T-helper type 1 cell therapy.

Yue Zhang, H. Ikeda, T. Iguchi, 2006, Cancer research.

Generation of human tumor-specific, HLA class I-restricted Th1 and Tc1 cells by cell engineering with tumor peptide-specific T cell receptor genes

H. Ikeda, H. Miyoshi, Y. Oka, 2005 .

Liposome-Encapsulated CpG Oligodeoxynucleotides as a Potent Adjuvant for Inducing Type 1 Innate Immunity

S. Akira, H. Ikeda, S. Kondo, 2004, Cancer Research.

Potential differentiation of tumor bearing mouse CD11b+Gr-1+ immature myeloid cells into both suppressor macrophages and immunostimulatory dendritic cells.

K. Chamoto, D. Wakita, T. Nishimura, 2009, Biomedical research.

Bevacizumab suppresses the growth of established non-small-cell lung cancer brain metastases in a hematogenous brain metastasis model

R. Nakamura, O. Kondoh, M. Monnai, 2019, Clinical & Experimental Metastasis.

Combination tumor immunotherapy with radiotherapy and Th1 cell therapy against murine lung carcinoma

M. Nishimura, H. Shirato, H. Dosaka-akita, 2007, Clinical & Experimental Metastasis.

unimmunized mice as novel immunomodulator of IFN-g-dependent type 1 immunity

Y. Togashi, S. Nishimura, D. Wakita, 2007 .

AsialoGM1+CD8+ central memory-type T cells in unimmunized mice as novel immunomodulator of IFN-gamma-dependent type 1 immunity.

Y. Togashi, S. Nishimura, D. Wakita, 2007, International immunology.

IFN-gamma-dependent type 1 immunity is crucial for immunosurveillance against squamous cell carcinoma in a novel mouse carcinogenesis model.

Y. Togashi, H. Shiku, H. Nishikawa, 2009, Carcinogenesis.

Th1 cell adjuvant therapy combined with tumor vaccination: a novel strategy for promoting CTL responses while avoiding the accumulation of Tregs.

Yue Zhang, K. Chamoto, D. Wakita, 2006, International immunology.

Tetramer‐blocking assay for defining antigen‐specific cytotoxic T lymphocytes using peptide‐MHC tetramer

M. Nishimura, H. Ikeda, H. Dosaka-akita, 2006, Cancer science.

Natural killer T cells from interleukin‐4‐deficient mice are defective in early interferon‐γ production in response to α‐galactosylceramide

Y. Iwakura, Y. Togashi, K. Chamoto, 2007 .

IL-6–dependent spontaneous proliferation is required for the induction of colitogenic IL-17–producing CD8+ T cells

Y. Iwakura, H. Ishigame, K. Chamoto, 2008, The Journal of experimental medicine.

Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation.

M. Fishbein, H. Kiyono, Shuang Chen, 2019, Immunity.

IFN‐γ elevates airway hyper‐responsiveness via up‐regulation of neurokinin A/neurokinin‐2 receptor signaling in a severe asthma model

Yasuo Shiohama, S. Ashino, D. Wakita, 2012, European journal of immunology.

Expression of the MAGE-A4 and NY-ESO-1 cancer-testis antigens and T cell infiltration in non-small cell lung carcinoma and their prognostic significance.

H. Ikeda, S. Kondo, M. Miyamoto, 2006, International journal of oncology.

of testosterone impairs anti-tumor neutrophil function.

M. Luu, E. Posadas, T. Crother, 2020 .

Abstract O.24: Gut Microflora Influences Pathology in the Kawasaki Disease Vasculitis Mouse Model

M. Fishbein, H. Kiyono, Shuang Chen, 2015 .

Neurokinin-2 Receptor Cell-Mediated Type 1 Immune Responses Neuropeptide Signaling Activates Dendritic

D. Wakita, H. Kitamura, T. Nishimura, 2012 .

CpG-ODN inhibits airway inflammation at effector phase through down-regulation of antigen-specific Th2-cell migration into lung.

Yue Zhang, K. Chamoto, S. Ashino, 2008, International immunology.

1α,25‐Dihydroxyvitamin D3 downmodulates the functional differentiation of Th1 cytokine‐conditioned bone marrow‐derived dendritic cells beneficial for cytotoxic T lymphocyte generation

Yue Zhang, H. Ikeda, J. Matsuzaki, 2006, Cancer science.

Effect of Bevacizumab on a Human Breast Cancer Model that Exhibited Palbociclib-resistance by RB Knockout.

Nobuyuki Ishikura, O. Kondoh, D. Wakita, 2022, Cancer diagnosis & prognosis.

Sialyl lewisx antigen‐expressing human CD4+ T and CD8+ T cells as initial immune responders in memory phenotype subsets

Yue Zhang, K. Chamoto, D. Wakita, 2008, Journal of leukocyte biology.

Neuropeptide Signaling Activates Dendritic Cell-Mediated Type 1 Immune Responses through Neurokinin-2 Receptor

D. Wakita, H. Kitamura, T. Nishimura, 2012, The Journal of Immunology.

Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL: its potentiation by combination with Th1 cell therapy.

H. Shirato, Y. Togashi, K. Chamoto, 2010, Cancer research.

Interleukin‐12‐responding asialoGM1+CD8+ central memory‐type T cells as precursor cells for interferon‐γ‐producing killer T cells

Y. Togashi, S. Nishimura, D. Wakita, 2006, Cancer science.

Toll-like receptor-dependent IL-12 production by dendritic cells is required for activation of natural killer cell-mediated Type-1 immunity induced by Chrysanthemum coronarium L.

Y. Aoyagi, K. Chamoto, S. Koizumi, 2011, International immunopharmacology.

The extract of Japanese soybean, Kurosengoku activates the production of IL-12 and IFN-γ by DC or NK1.1(+) cells in a TLR4- and TLR2-dependent manner.

Y. Aoyagi, K. Chamoto, S. Koizumi, 2011, Cellular immunology.

Phagocytosis of Liposome Particles by Rat Splenic Immature Monocytes Makes Them Transiently and Highly Immunosuppressive In Ex Vivo Culture Conditions

H. Horinouchi, M. Fujihara, H. Azuma, 2011, Journal of Pharmacology and Experimental Therapeutics.

IL-17/IFN-γ double producing CD8+ T (Tc17/IFN-γ) cells: a novel cytotoxic T-cell subset converted from Tc17 cells by IL-12.

D. Wakita, H. Kitamura, T. Nishimura, 2011, International immunology.

IL-17 / IFN-g double producing CD 8 1 T ( Tc 17 / IFN-g ) cells : A novel cytotoxic T-cell subset converted from Tc 17 cells by IL-12

D. Wakita, H. Kitamura, T. Nishimura, 2011 .

Tumor‐infiltrating IL‐17‐producing γδ T cells support the progression of tumor by promoting angiogenesis

Y. Iwakura, H. Nishikawa, K. Chamoto, 2010, European journal of immunology.

First clinical trial of cancer vaccine therapy with artificially synthesized helper/ killer‐hybrid epitope long peptide of MAGE‐A4 cancer antigen

S. Todo, Y. Togashi, D. Wakita, 2012, Cancer science.

The development of IL‐17/IFN‐γ‐double producing CTLs from Tc17 cells is driven by epigenetic suppression of Socs3 gene promoter

D. Wakita, H. Kitamura, T. Nishimura, 2012, European journal of immunology.

Cisplatin Augments Antitumor T-Cell Responses Leading to a Potent Therapeutic Effect in Combination With PD-L1 Blockade

Miho Suzuki, T. Iwai, S. Harada, 2019, AntiCancer Research.

The Key Role of IL-6–Arginase Cascade for Inducing Dendritic Cell–Dependent CD4+ T Cell Dysfunction in Tumor-Bearing Mice

S. Terada, D. Wakita, H. Kitamura, 2013, The Journal of Immunology.

Anti‐IL‐6 receptor mAb eliminates myeloid‐derived suppressor cells and inhibits tumor growth by enhancing T‐cell responses

S. Terada, D. Wakita, H. Kitamura, 2012, European journal of immunology.

Potentiation of cytotoxic activity in naïve and tumor-bearing mice by oral administration of hot-water extracts from Agaricus brazei fruiting bodies.

Y. Kumazawa, H. Takimoto, K. Kawaguchi, 2004, Biological & pharmaceutical bulletin.

Loss of testosterone impairs anti-tumor neutrophil function

M. Luu, E. Posadas, M. Noval Rivas, 2019, Nature Communications.

Cell Dysfunction in Tumor-Bearing Mice Dependent CD4+ T - Inducing Dendritic Cell Arginase Cascade for - The Key Role of IL-6

S. Terada, D. Wakita, H. Kitamura, 2013 .

Interaction of NK cells with bacteria

T. Ikeda, K. Chamoto, S. Koizumi, 2010 .

1α,25-Dihydroxyvitamin D3 and all-trans retinoic acid synergistically inhibit the differentiation and expansion of Th17 cells.

Y. Iwakura, K. Chamoto, D. Wakita, 2010, Immunology letters.

Topoisomerase I inhibitor, irinotecan, depletes regulatory T cells and up-regulates MHC class I and PD-L1 expression, resulting in a supra-additive antitumor effect when combined with anti-PD-L1 antibodies

T. Iwai, D. Wakita, Masamichi Sugimoto, 2018, Oncotarget.

Role of Interleukin-1 Signaling in a Mouse Model of Kawasaki Disease–Associated Abdominal Aortic Aneurysm

M. Fishbein, P. Shah, Debiao Li, 2016, Arteriosclerosis, thrombosis, and vascular biology.

T‐Cell‐Intrinsic Receptor Interacting Protein 2 Regulates Pathogenic T Helper 17 Cell Differentiation

Chihiro Ogawa, Shuang Chen, D. Unutmaz, 2018, Immunity.

Blocking of IL-6 signaling pathway prevents CD4+ T cell-mediated colitis in a T(h)17-independent manner.

Yue Zhang, Y. Iwakura, K. Chamoto, 2007, International immunology.

The critical role of type‐1 innate and acquired immunity in tumor immunotherapy

H. Ikeda, K. Chamoto, T. Tsuji, 2004, Cancer science.

PD-L1 blockade exhibits anti-tumor effect on brain metastasis by activating CD8+ T cells in hematogenous metastasis model with lymphocyte infusion

O. Kondoh, D. Wakita, Masamichi Sugimoto, 2021, Clinical & Experimental Metastasis.

A T(h)17-polarized cell population that has infiltrated the lung requires cells that convert to IFN-{gamma} production in order to induce airway hyperresponsiveness.

Y. Iwakura, Yasuo Shiohama, K. Chamoto, 2010, International immunology.

Bevacizumab suppresses the growth of established non-small-cell lung cancer brain metastases in a hematogenous brain metastasis model

R. Nakamura, O. Kondoh, M. Monnai, 2019, Clinical & Experimental Metastasis.

Blockade of IL-6-signaling inhibits the pathogenesis of CD4+ T cell-mediated lethal graft-versus-host reaction against minor histocompatibility antigen.

K. Chamoto, D. Wakita, H. Kitamura, 2011, Immunology letters.

Artificially synthesized helper/killer-hybrid epitope long peptide (H/K-HELP): preparation and immunological analysis of vaccine efficacy.

Y. Togashi, D. Wakita, H. Kitamura, 2015, Immunology letters.

Abstract 1459: Revealing the underlying causes of the gender disparity in melanoma: Role of testosterone

T. Crother, M. Arditi, J. Markman, 2016 .