M. Larsen

发表

Linked expression of Ah receptor, ARNT, CYP1A1, and CYP1B1 in rat mammary epithelia, in vitro, is each substantially elevated by specific extracellular matrix interactions that precede branching morphogenesis.

C. Jefcoate, R. Pollenz, M. Larsen, 2004, Toxicological sciences : an official journal of the Society of Toxicology.

TCDD elevates erbB2 expression and signaling in T47D cells by reversing serum potentiation of estrogen receptor activity, independent of estrogen levels and enhanced ER down-regulation

C. Jefcoate, M. Larsen, W. G. Angus, 2000, Molecular and Cellular Endocrinology.

Expression of CYP1A1 and CYP1B1 depends on cell-specific factors in human breast cancer cell lines: role of estrogen receptor status.

C. Jefcoate, M. Larsen, W. G. Angus, 1999, Carcinogenesis.

Characterization of CYP1B1 and CYP1A1 expression in human mammary epithelial cells: role of the aryl hydrocarbon receptor in polycyclic aromatic hydrocarbon metabolism.

C. Jefcoate, S. Eltom, K. A. Sukow, 1998, Cancer research.

Cytochrome P4501B1 in bone marrow is co-expressed with key markers of mesenchymal stem cells. BMS2 cell line models PAH disruption of bone marrow niche development functions

C. Rondelli, C. Jefcoate, Tie-gang Tong, 2020, Toxicology and Applied Pharmacology.

Diet-dependent retinoid effects on liver gene expression include stellate and inflammation markers and parallel effects of the nuclear repressor Shp.

C. Jefcoate, S. Tanumihardjo, Meghan L. Maguire, 2017, The Journal of nutritional biochemistry.

Cyp1b1 affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4α and PPARα.

C. Jefcoate, Meghan L. Maguire, M. Larsen, 2016, Archives of biochemistry and biophysics.

PAHs Target Hematopoietic Linages in Bone Marrow through Cyp1b1 Primarily in Mesenchymal Stromal Cells but Not AhR: A Reconstituted In Vitro Model

C. Rondelli, C. Jefcoate, C. Czuprynski, 2016, Stem cells international.

Acute Disruption of Bone Marrow Hematopoiesis by Benzo(a)pyrene Is Selectively Reversed by Aryl Hydrocarbon Receptor-Mediated Processes

C. Jefcoate, C. Czuprynski, M. Larsen, 2011, Molecular Pharmacology.

The induction of five rat hepatic P450 cytochromes by phenobarbital and similarly acting compounds is regulated by a sexually dimorphic, dietary-dependent endocrine factor that is highly strain specific.

C. Jefcoate, M. Larsen, P. Brake, 1994, Archives of biochemistry and biophysics.

Structure-dependent induction of CYP2B by polychlorinated biphenyl congeners in female Sprague-Dawley rats.

S. Safe, C. Jefcoate, K. Connor, 1995, Biochemical pharmacology.

StAR, a bridge from ApoE, LDL, and HDL cholesterol trafficking to mitochondrial metabolism

C. Jefcoate, M. Larsen, 2019, Current Opinion in Endocrine and Metabolic Research.

Distinctive functioning of STARD1 in the fetal Leydig cells compared to adult Leydig and adrenal cells. Impact of Hedgehog signaling via the primary cilium

C. Jefcoate, Anbarasi Kothandapani, J. Jorgensen, 2021, Molecular and Cellular Endocrinology.

STARD1 Functions in Mitochondrial Cholesterol Metabolism and Nascent HDL Formation. Gene Expression and Molecular mRNA Imaging Show Novel Splicing and a 1:1 Mitochondrial Association

C. Jefcoate, J. Jorgensen, Jinwoo Lee, 2020, Frontiers in Endocrinology.

Cyp1b1 exerts opposing effects on intestinal tumorigenesis via exogenous and endogenous substrates.

C. Jefcoate, L. Clipson, R. Halberg, 2008, Cancer research.

Cyp1b1‐mediated suppression of lymphoid progenitors in bone marrow by polycyclic aromatic hydrocarbons coordinately impacts spleen and thymus: a selective role for the Ah Receptor

C. Rondelli, C. Jefcoate, E. Forsberg, 2016, Pharmacology research & perspectives.

Cytochrome P450 1B1: An unexpected modulator of liver fatty acid homeostasis.

S. Reeder, V. Adhami, H. Mukhtar, 2015, Archives of biochemistry and biophysics.

Generation of Reactive Metabolites and Associated DNA Adducts from Benzene, Butadiene, and PAH in Bone Marrow. Their Effects on Hematopoiesis and Impact on Human Health

C. Jefcoate, M. Larsen, 2008 .

Tunable regulation of CREB DNA binding activity couples genotoxic stress response and metabolism

P. Bushel, Adam S. Mastrocola, R. Tibbetts, 2016, Nucleic acids research.

Expression of CYP1B1 but not CYP1A1 by primary cultured human mammary stromal fibroblasts constitutively and in response to dioxin exposure: role of the Ah receptor.

C. Jefcoate, S. Eltom, M. Larsen, 1998, Carcinogenesis.

Cyp1b1 deletion and retinol deficiency coordinately suppress mouse liver lipogenic genes and hepcidin expression during post-natal development

C. Jefcoate, S. Tanumihardjo, M. Larsen, 2017, Molecular and Cellular Endocrinology.

Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development

L. Quadro, C. Jefcoate, S. Tanumihardjo, 2020, PloS one.

Lipidomics Reveals a Link between CYP1B1 and SCD1 in Promoting Obesity

Fei Li, Frank J. Gonzalez, Changtao Jiang, 2014, Journal of proteome research.

Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene.

W. Baird, F. Gonzalez, C. Jefcoate, 2000, Cancer research.

Cytochrome P 4501 B 1 Mediates Induction of Bone Marrow Cytotoxicity and Preleukemia Cells in Mice Treated with 7 , 12-Dimethylbenz [ a ] anthracene 1

W. Baird, F. Gonzalez, C. Jefcoate, 2000 .

Role of cytochrome P450 enzyme induction in the metabolic activation of benzo[c]phenanthrene in human cell lines and mouse epidermis.

D. Jerina, S. Amin, W. Baird, 1997, Chemical research in toxicology.

Bone marrow lymphoid and myeloid progenitor cells are suppressed in 7,12-dimethylbenz(a)anthracene (DMBA) treated mice.

C. Jefcoate, C. Czuprynski, M. Larsen, 2010, Toxicology.

Targeted deletion of Cyp1b1 in pericytes results in attenuation of retinal neovascularization and trabecular meshwork dysgenesis.

Hao F. Zhang, L. Teixeira, C. Sorenson, 2019, Trends in developmental biology.

AhR and CYP1B1 Control Oxygen Effects on Bone Marrow Progenitor Cells: The Enrichment of Multiple Olfactory Receptors as Potential Microbiome Sensors

P. Dansette, M. Larsen, A. N’jai, 2023, International journal of molecular sciences.