J. Inshaw

发表

Approaches and advances in the genetic causes of autoimmune disease and their implications

J. Todd, O. Burren, A. Cutler, 2018, Nature Immunology.

An integrated platform to systematically identify causal variants and genes for polygenic human traits

Calliope A. Dendrou, J. Todd, G. Lunter, 2019, bioRxiv.

The impact of proinflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes

J. Todd, M. Esteller, P. Marchetti, 2019, Nature Genetics.

Virological remission after antiretroviral therapy interruption in female African HIV seroconverters

H. Rees, P. Kaleebu, G. Ramjee, 2019, AIDS.

Childhood body size directly increases type 1 diabetes risk based on a lifecourse Mendelian randomization approach

Catherine C. Robertson, J. Todd, F. Cucca, 2022, Nature Communications.

Analysis of overlapping genetic association in type 1 and type 2 diabetes

M. McCarthy, J. Todd, A. Mahajan, 2020, bioRxiv.

PRF1 mutation alters immune system activation, inflammation, and risk of autoimmunity

Catherine C. Robertson, G. Abecasis, D. Schlessinger, 2020, Multiple sclerosis.

Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration

J. Todd, D. Dunger, S. Richardson, 2022, Diabetes.

Childhood body size directly increases type 1 diabetes risk based on a lifecourse randomization approach.

Catherine C. Robertson, J. Todd, F. Cucca, 2022 .

Brief Report: Enhanced Normalization of CD4/CD8 Ratio With Earlier Antiretroviral Therapy at Primary HIV Infection

P. Kaleebu, J. Miro, D. Cooper, 2016, Journal of acquired immune deficiency syndromes.

Enhanced normalisation of CD4/CD8 ratio with early antiretroviral therapy in primary HIV infection

P. Kaleebu, D. Cooper, J. Weber, 2014, Journal of the International AIDS Society.

Enhanced Normalization of CD 4 / CD 8 Ratio With Earlier Antiretroviral Therapy at Primary HIV Infection

P. Kaleebu, J. Miro, D. Cooper, 2022 .

The Impact of HCV Infection Duration on HIV Disease Progression and Response to cART amongst HIV Seroconverters in the UK

D. Hawkins, C. Leen, A. Phillips, 2015, PLoS ONE.

A Global-Local Approach for Detecting Hotspots in Multiple-Response Regression.

Anthony C. Davison, Sylvia Richardson, Leonardo Bottolo, 2018, The annals of applied statistics.

BREATHER (PENTA 16) short-cycle therapy (SCT) (5 days on/2 days off) in young people with chronic human immunodeficiency virus infection: an open, randomised, parallel-group Phase II/III trial.

T. Rhodes, N. Klein, D. Gibb, 2016, Health technology assessment.

The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes

J. Todd, M. Esteller, P. Marchetti, 2019, Nature Genetics.

Fine-mapping, trans-ancestral, and genomic analyses identify causal variants, cells, genes, and drug targets for type 1 diabetes

Amy S. Shah, Catherine C. Robertson, P. Deloukas, 2020, Nature Genetics.

Thymocyte regulatory variant alters transcription factor binding and protects from type 1 diabetes in infants

J. Todd, M. Pekalski, N. Sandholm, 2021, Scientific Reports.

The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age

J. Todd, N. Walker, C. Wallace, 2017, Diabetologia.

Comparison of methods for transcriptome imputation through application to two common complex diseases

Heather J. Cordell, Andrew P. Morris, Jamie Inshaw, 2018, European Journal of Human Genetics.

Disentangling the direct and indirect effects of childhood adiposity on type 1 diabetes and immune-associated diseases: a multivariable Mendelian randomization study

Catherine C. Robertson, J. Todd, F. Cucca, 2021, medRxiv.

Specific type 1 diabetes risk genes underpin age-at-diagnosis and indicate joint defects in immunity, beta-cell fragility and responses to viral infections in early-onset disease

J. Todd, L. Wicker, D. Crouch, 2019, bioRxiv.

Weekends-off efavirenz-based antiretroviral therapy in HIV-infected children, adolescents, and young adults (BREATHER): a randomised, open-label, non-inferiority, phase 2/3 trial

C. Giaquinto, N. Klein, T. Bunupuradah, 2016, The lancet. HIV.

International Congress of Drug Therapy in HIV Infection 2‐6 November 2014, Glasgow, UK

Samit R. Joshi, Charlene A Flash, Thomas Lengauer, 2014 .

Genetic Variants Predisposing Most Strongly to Type 1 Diabetes Diagnosed Under Age 7 Years Lie Near Candidate Genes That Function in the Immune System and in Pancreatic β-Cells

J. Todd, L. Wicker, D. Crouch, 2019, Diabetes Care.

Correction: Comparison of methods for transcriptome imputation through application to two common complex diseases

A. Morris, H. Cordell, James J. Fryett, 2020, European Journal of Human Genetics.

Anti-inflammatory therapy with nebulised dornase alfa in patients with severe COVID-19 pneumonia

V. Johnston, H. Esmail, R. Evans, 2022, medRxiv.

Enhanced genetic analysis of type 1 diabetes by selecting variants on both effect size and significance, and by integration with autoimmune thyroid disease

Catherine C. Robertson, J. Todd, Wei-Min Chen, 2021, bioRxiv.

Phase 2 Dose-Finding Study in Patients with Gout Using SEL-212, a Novel PEGylated Uricase (SEL-037) Combined with Tolerogenic Nanoparticles (SEL-110)

S. Nicolaou, Hyon K. Choi, P. Traber, 2023, Rheumatology and Therapy.

Pharmacokinetics of Pediatric Lopinavir/Ritonavir Tablets in Children When Administered Twice Daily According to FDA Weight Bands

C. Königs, C. Giaquinto, H. Lyall, 2014, The Pediatric infectious disease journal.

The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides new insights into the genetics of type 1 diabetes

J. Todd, M. Esteller, P. Marchetti, 2019, bioRxiv.

Analysis From Phase II Clinical Trial, Alvelestat, NE (Neutrophil Elastase) Inhibitor in AATD-LD: Correlation Between Biomarker Response (Desmosine and Aa-val360) and Clinical Outcome (SGRQ)

J. Parkin, J. Inshaw, S. Rabbie, 2023, B22. NEW TREATMENTS AND NOVEL TARGETS FOR COPD AND ALPHA-1.

Nucleoside/nucleotide reverse transcriptase inhibitor sparing regimen with once daily integrase inhibitor plus boosted darunavir is non-inferior to standard of care in virologically-suppressed children and adolescents living with HIV – Week 48 results of the randomised SMILE Penta-17-ANRS 152 clinic

J. Blackstone, E. Williams, C. Giaquinto, 2023, EClinicalMedicine.

Approaches and advances in the genetic causes of autoimmune disease and their implications

J. Todd, O. Burren, A. Cutler, 2018, Nature Immunology.

Approaches and advances in the genetic causes of autoimmune disease 1 and their implications 2

O. Burren, A. Cutler, J. Inshaw, 2019 .

A Global-Local Approach for Detecting Hotspots in Multiple-Response Regression.

S. Richardson, A. Davison, L. Bottolo, 2018, The annals of applied statistics.

The effect of HCV infection duration on HIV disease progression

D. Hawkins, C. Leen, A. Phillips, 2014 .