D. Gomez

发表

TRF2/RAP1 and DNA–PK mediate a double protection against joining at telomeric ends

E. Gilson, P. Frit, P. Calsou, 2010, The EMBO journal.

G-quadruplexes unfolding by RHAU helicase.

J. Mergny, A. Bourdoncle, O. Mendoza, 2017, Biochimica et biophysica acta. General subjects.

Telomerase and Telomere Interacting Agents

J. Mergny, L. Lacroix, J. Riou, 2007 .

CNBP controls transcription by unfolding DNA G-quadruplex structures

P. Armas, N. Calcaterra, A. Binolfi, 2019, Nucleic acids research.

The integration of nitrogen and carbon catabolite repression in Aspergillus nidulans requires the GATA factor AreA and an additional positive‐acting element, ADA

C. Scazzocchio, B. Cubero, D. Gomez, 1997, The EMBO journal.

The DNA-Binding Polyamine Moiety in the Vectorized DNA Topoisomerase II Inhibitor F14512 Alters Reparability of the Consequent Enzyme-Linked DNA Double-Strand Breaks

P. Frit, B. Gomes, P. Calsou, 2017, Molecular Cancer Therapeutics.

Targeting human telomerase for cancer therapeutics

J. Mergny, E. Mandine, L. Lacroix, 2004, Cytotechnology.

The G-quadruplex ligand telomestatin inhibits POT1 binding to telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells.

K. Shin‐ya, M. O'Donohue, P. Koebel, 2006, Cancer research.

Interaction of Telomestatin with the Telomeric Single-strand Overhang*

K. Shin‐ya, J. Mergny, J. Riou, 2004, Journal of Biological Chemistry.

Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescence

J. Zahm, M. O'Donohue, J. Riou, 2005, Nucleic acids research.

Resistance to the Short Term Antiproliferative Activity of the G-quadruplex Ligand 12459 Is Associated with Telomerase Overexpression and Telomere Capping Alteration*

K. Shin‐ya, J. Mergny, L. Lacroix, 2003, Journal of Biological Chemistry.

DNA damage signaling induced by the G-quadruplex ligand 12459 is modulated by PPM1D/WIP1 phosphatase

J. Riou, Céline Douarre, C. Trentesaux, 2013, Nucleic acids research.

Effects of a halogenated G-quadruplex ligand from the pyridine dicarboxamide series on the terminal sequence of XpYp telomere in HT1080 cells.

M. Teulade‐Fichou, J. Riou, C. Trentesaux, 2012, Biochimie.

Chromatin Rearrangements in the prnD-prnB Bidirectional Promoter: Dependence on Transcription Factors

C. Scazzocchio, I. García, D. Gomez, 2004, Eukaryotic Cell.

J. Mergny, E. Mandine, J. Riou, 2005, Oncogene.

Telomestatin-induced Telomere Uncapping Is Modulated by POT1 through G-overhang Extension in HT1080 Human Tumor Cells*

Hamid Morjani, Kazuo Shin-Ya, K. Shin‐ya, 2006, Journal of Biological Chemistry.

Preferential binding of a G-quadruplex ligand to human chromosome ends

B. Dutrillaux, J. Mergny, E. Mandine, 2005, Nucleic acids research.

Transcription-associated topoisomerase activities control DNA-breaks production by G-quadruplex ligands

O. Bouchez, C. Noirot, J. Riou, 2020, bioRxiv.

Detection of telomerase inhibitors based on g-quadruplex ligands by a modified telomeric repeat amplification protocol assay.

Jean-Louis Mergny, J. Mergny, J. Riou, 2002, Cancer research.

Stabilization of the c-myc gene promoter quadruplex by specific ligands' inhibitors of telomerase.

Patrick Mailliet, E. Mandine, J. Riou, 2004, Biochemical and biophysical research communications.

G-Quadruplex binding optimization by gold(iii) insertion into the center of a porphyrin.

J. Mergny, P. Calsou, G. Pratviel, 2019, Dalton transactions.

Efficient Inhibition of Telomerase by Nickel–Salophen Complexes

T. Lavergne, J. Mergny, F. Thomas, 2016, ChemMedChem.

Interaction of polycationic Ni(II)-salophen complexes with G-quadruplex DNA.

C. Philouze, J. Mergny, F. Thomas, 2014, Inorganic chemistry.

Improvement of porphyrins for G-quadruplex DNA targeting.

P. Dumy, R. Bonnet, Jung-Hsin Lin, 2011, Biochimie.

Effects of the histone deacetylase inhibitor trichostatin A on nuclear texture and c‐jun gene expression in drug‐sensitive and drug‐resistant human H69 lung carcinoma cells

A. Trussardi-Régnier, J. Dufer, V. El-Khoury, 2004, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

A G-quadruplex structure within the 5′-UTR of TRF2 mRNA represses translation in human cells

J. Mergny, M. Teulade‐Fichou, J. Riou, 2010, Nucleic acids research.

Alternative end-joining pathway(s): bricolage at DNA breaks.

P. Frit, P. Calsou, D. Gomez, 2014, DNA repair.

Constrained G4 structures unveil topology specificity of known and new G4 binding proteins

T. Lavergne, Y. Couté, A. Adrait, 2021, Scientific Reports.

Transcription-associated topoisomerase 2α (TOP2A) activity is a major effector of cytotoxicity induced by G-quadruplex ligands

O. Bouchez, C. Noirot, J. Riou, 2021, eLife.

Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing.

J. Mergny, L. Lacroix, J. Riou, 2004, Nucleic acids research.

Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase.

K. Shin‐ya, J. Tazi, J. Riou, 2003, Cancer research.

Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks

P. Frit, P. Calsou, B. Salles, 2011, Nucleic acids research.

A New Steroid Derivative Stabilizes G-Quadruplexes and Induces Telomere Uncapping in Human Tumor Cells

Jean-Louis Mergny, J. Mergny, J. Riou, 2007, Molecular Pharmacology.

The nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells

J. Mergny, E. Defrancq, P. Calsou, 2015, JBIC Journal of Biological Inorganic Chemistry.

Topoisomerase IIIα is required for normal proliferation and telomere stability in alternative lengthening of telomeres

E. Gilson, J. Riou, A. Londoño-Vallejo, 2008, The EMBO journal.

Multiple GATA sites: protein binding and physiological relevance for the regulation of the proline transporter gene of Aspergillus nidulans

C. Scazzocchio, B. Cubero, I. García, 2003, Molecular microbiology.

Advances in Brief Resistance to Senescence Induction and Telomere Shortening by a G-Quadruplex Ligand Inhibitor of Telomerase 1

K. Shin‐ya, J. Tazi, J. Riou, 2003 .

PrnA, a Zn2Cys6 activator with a unique DNA recognition mode, requires inducer for in vivo binding

C. Scazzocchio, B. Cubero, G. Cecchetto, 2002, Molecular microbiology.

G-quadruplexes unfolding by RHAU helicase.

J. Mergny, A. Bourdoncle, O. Mendoza, 2017, Biochimica et biophysica acta. General subjects.

TRF2/RAP1 and DNA–PK mediate a double protection against joining at telomeric ends

E. Gilson, P. Frit, P. Calsou, 2010, The EMBO journal.