A. Neves-Carvalho

发表

The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis

A. Chakraborty, T. Pandita, A. Koeppen, 2015, PLoS genetics.

Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease.

Renee M. Brielmann, R. Morimoto, P. Maciel, 2015, Brain : a journal of neurology.

Neuron-specific proteotoxicity of mutant ataxin-3 in C. elegans: rescue by the DAF-16 and HSF-1 pathways.

R. Morimoto, P. Maciel, M. Ailion, 2011, Human molecular genetics.

Polyglutamine spinocerebellar ataxias: emerging therapeutic targets

P. Maciel, S. Duarte-Silva, A. Teixeira-Castro, 2020, Expert opinion on therapeutic targets.

Absence of Ataxin-3 Leads to Enhanced Stress Response in C. elegans

G. Corthals, E. Logarinho, P. Maciel, 2011, PloS one.

Neuroprotective Effects of Creatine in the CMVMJD135 Mouse Model of Spinocerebellar Ataxia Type 3

C. Soares-Cunha, P. Maciel, J. Silva, 2018, Movement disorders : official journal of the Movement Disorder Society.

Regulation of neuronal mRNA splicing and Tau isoform ratio by ATXN 3 1 through deubiquitylation of splicing factors 2 RUNNING TITLE : Neuronal splicing regulation by ATXN 3 3 4

P. Heutink, K. Li, J. Silva, 2019 .

Preclinical Assessment of Mesenchymal-Stem-Cell-Based Therapies in Spinocerebellar Ataxia Type 3

A. Salgado, C. Soares-Cunha, P. Maciel, 2021, Biomedicines.

Chronic Treatment with 17-DMAG Improves Balance and Coordination in A New Mouse Model of Machado-Joseph Disease

C. Soares-Cunha, P. Maciel, A. Silva-Fernandes, 2014, Neurotherapeutics.

Lithium Chloride Therapy Fails to Improve Motor Function in a Transgenic Mouse Model of Machado-Joseph Disease

C. Soares-Cunha, P. Maciel, A. Silva-Fernandes, 2014, The Cerebellum.

Profiling Microglia in a Mouse Model of Machado–Joseph Disease

Bruno José Torres Fernandes, P. Maciel, J. Relvas, 2022, Biomedicines.

Combined therapy with m-TOR-dependent and -independent autophagy inducers causes neurotoxicity in a mouse model of Machado–Joseph disease

C. Soares-Cunha, P. Maciel, A. Silva-Fernandes, 2016, Neuroscience.

COMBINED THERAPY WITH mTOR-DEPENDENT AND-INDEPENDENT AUTOPHAGY INDUCERS CAUSES NEUROTOXICITY IN A MOUSE MODEL OF MACHADO – JOSEPH DISEASE

C. Soares-Cunha, P. Maciel, A. Silva-Fernandes, 2015 .

Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology

C. Soares-Cunha, N. Sousa, A. Takashima, 2018, Cell Death & Differentiation.

Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease

P. Maciel, A. Rego, A. Silva-Fernandes, 2015, PloS one.

Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells.

H. Paulson, P. Heutink, E. Logarinho, 2015, Human molecular genetics.

Cerebellar neuronal dysfunction accompanies early motor symptoms in spinocerebellar ataxia type 3

K. Khodakhah, P. Maciel, A. Neves-Carvalho, 2021, bioRxiv.

Secretome of Mesenchymal Progenitors from the Umbilical Cord Acts as Modulator of Neural/Glial Proliferation and Differentiation

A. Salgado, N. Sousa, L. Pinto, 2014, Stem Cell Reviews and Reports.

Regulation of neuronal mRNA splicing and Tau isoform ratio by ATXN3 through deubiquitylation of splicing factors

P. Heutink, P. Maciel, A. Carvalho, 2019, bioRxiv.

The Secretome of Bone Marrow and Wharton Jelly Derived Mesenchymal Stem Cells Induces Differentiation and Neurite Outgrowth in SH-SY5Y Cells

A. Salgado, N. Sousa, N. Sousa, 2014, Stem cells international.

ATX-3, CDC-48 and UBXN-5: a new trimolecular complex in Caenorhabditis elegans.

G. Corthals, E. Logarinho, P. Maciel, 2009, Biochemical and biophysical research communications.

Levetiracetam treatment leads to functional recovery after thoracic or cervical injuries of the spinal cord

A. Salgado, N. Silva, A. Neves-Carvalho, 2021, NPJ Regenerative medicine.

Genetic Ablation of Inositol 1,4,5-Trisphosphate Receptor Type 2 (IP3R2) Fails to Modify Disease Progression in a Mouse Model of Spinocerebellar Ataxia Type 3

João Filipe Viana, J. Oliveira, J. Correia, 2023, International journal of molecular sciences.

Dysregulation of autophagy and stress granule-related proteins 1 in stress-driven Tau pathology 2 3 Running

C. Soares-Cunha, A. Takashima, N. Sousa, 2018 .

Levetiracetam treatment leads to functional recovery after thoracic or cervical injuries of the spinal cord

A. Salgado, N. Silva, A. Neves-Carvalho, 2021, npj Regenerative Medicine.

Selective impact of Tau loss on nociceptive primary afferents and pain sensation

N. Sousa, H. Leite-Almeida, A. Almeida, 2014, Experimental Neurology.