Z. Ying

发表

p62/Sequestosome 1 Regulates Aggresome Formation of Pathogenic Ataxin-3 with Expanded Polyglutamine

F. Gao, Dong Chen, Liang Zhou, 2014, International journal of molecular sciences.

SUMO-1 modification increases human SOD1 stability and aggregation

Ming Yan, X. Yao, Tao Zhang, 2006, Neurosciences research.

SUMO-1 modification increases human SOD1 stability and aggregation

X. Yao, Tao Zhang, Yunyu Shi, 2006, Neuroscience Research.

Casein kinase 2 interacts with and phosphorylates ataxin-3

E. Fei, Hongfeng Wang, Z. Ying, 2008, Neuroscience Bulletin.

Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation.

Guanghui Wang, Xiaodong Zhu, Jia-wei Zhou, 2009, Human molecular genetics.

Loss of TDP-43 Inhibits Amyotrophic Lateral Sclerosis-Linked Mutant SOD1 Aggresome Formation in an HDAC6-Dependent Manner

Hongfeng Wang, Z. Ying, Guanghui Wang, 2015 .

A critical role of Hrd1 in the regulation of optineurin degradation and aggresome formation

Guanghui Wang, Chunfeng Liu, Hongfeng Wang, 2017, Human molecular genetics.

Ataxin-3 Regulates Aggresome Formation of Copper-Zinc Superoxide Dismutase (SOD1) by Editing K63-linked Polyubiquitin Chains*

Guanghui Wang, Hongfeng Wang, Z. Ying, 2012, The Journal of Biological Chemistry.

Gefitinib facilitates PINK1/Parkin-mediated mitophagy by enhancing mitochondrial recruitment of OPTN

Zengli Zhang, Hongfeng Wang, Z. Ying, 2022, Fundamental research.

Sumoylation is critical for DJ‐1 to repress p53 transcriptional activity

Jun Fan, P. Jiang, H. Ren, 2008, FEBS letters.

Ibudilast enhances the clearance of SOD1 and TDP-43 aggregates through TFEB-mediated autophagy and lysosomal biogenesis: The new molecular mechanism of ibudilast and its implication for neuroprotective therapy.

Hongfeng Wang, Z. Ying, Q. Gao, 2020, Biochemical and biophysical research communications.

The Endoplasmic Reticulum (ER)-associated Degradation System Regulates Aggregation and Degradation of Mutant Neuroserpin*

Guanghui Wang, Huadong Fan, Hongfeng Wang, 2011, The Journal of Biological Chemistry.

Increased mitophagy protects cochlear hair cells from aminoglycoside-induced damage

Shan Sun, R. Chai, X. Qian, 2022, Autophagy.

Degradation of TDP-43 and its pathogenic form by autophagy and the ubiquitin-proteasome system

Bin Li, Huadong Fan, Hongfeng Wang, 2010, Neuroscience Letters.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

PolyQ-expanded ataxin-3 interacts with full-length ataxin-3 in a polyQ length-dependent manner

E. Fei, Hongfeng Wang, Z. Ying, 2008, Neuroscience bulletin.

C9orf72 associates with inactive Rag GTPases and regulates mTORC1‐mediated autophagosomal and lysosomal biogenesis

Xuechu Zhen, J. Prehn, Guanghui Wang, 2020, Aging cell.

Autophagy and Ubiquitin-Proteasome System Coordinate to Regulate the Protein Quality Control of Neurodegenerative Disease-Associated DCTN1

Guanghui Wang, Hongfeng Wang, Z. Ying, 2019, Neurotoxicity Research.

Bcl-2-dependent upregulation of autophagy by sequestosome 1/p62 in vitro

F. Gao, H. Ren, Dong Chen, 2013, Acta Pharmacologica Sinica.

Ataxin-3 protects cells against H2O2-induced oxidative stress by enhancing the interaction between Bcl-XL and Bax

H. Ren, P. Wang, Z. Ying, 2013, Neuroscience.

Somatic and germline mutations in the tumor suppressor gene PARK2 impair PINK1/Parkin-mediated mitophagy in lung cancer cells

Q. Ma, Zeng-li Zhang, Hongfeng Wang, 2019, Acta Pharmacologica Sinica.

Curcumin induces apoptosis in human lung adenocarcinoma A549 cells through a reactive oxygen species-dependent mitochondrial signaling pathway.

Kedi Xu, Qingyong Chen, Lijun Wu, 2009, Oncology reports.

The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy

C. Dong, K. Tam, Mian Cao, 2022, The Journal of biological chemistry.

Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity.

Zhouteng Tao, Guoqiang Xu, Hongfeng Wang, 2015, Human molecular genetics.

Oxidation of multiple MiT/TFE transcription factors links oxidative stress to transcriptional control of autophagy and lysosome biogenesis

J. Prehn, Guanghui Wang, Hongfeng Wang, 2019, Autophagy.

Folliculin, a tumor suppressor associated with Birt-Hogg-Dubé (BHD) syndrome, is a novel modifier of TDP-43 cytoplasmic translocation and aggregation.

Hongfeng Wang, Z. Ying, Guanghui Wang, 2016, Human molecular genetics.

TDP‐43 loss of function increases TFEB activity and blocks autophagosome–lysosome fusion

F. Gao, H. Ren, Guanghui Wang, 2015, The EMBO journal.

Regulation of autophagic flux by CHIP

F. Gao, H. Ren, Dong Chen, 2015, Neuroscience Bulletin.

The development of the protein inhibitor of activated STAT

Z. Ying, 2010 .

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases

David S. Park, S. Lipton, C. Culmsee, 2017, Cell Death & Differentiation.

Autophagy and Ubiquitin-Proteasome System Coordinate to Regulate the Protein Quality Control of Neurodegenerative Disease-Associated DCTN1

Guanghui Wang, Hongfeng Wang, Z. Ying, 2019, Neurotoxicity Research.

The ubiquitin proteasome system as a potential target for the treatment of neurodegenerative diseases.

Guanghui Wang, Hongfeng Wang, Z. Ying, 2013, Current pharmaceutical design.

Bcl-2 Decreases the Affinity of SQSTM1/p62 to Poly-Ubiquitin Chains and Suppresses the Aggregation of Misfolded Protein in Neurodegenerative Disease

H. Ren, Liang Zhou, Hongfeng Wang, 2015, Molecular Neurobiology.

Intermittent Starvation Promotes Maturation of Human Embryonic Stem Cell-Derived Cardiomyocytes

W. Lei, Zhen-Ao Zhao, Shijun Hu, 2021, Frontiers in Cell and Developmental Biology.

Bcl-2 Decreases the Affinity of SQSTM1/p62 to Poly-Ubiquitin Chains and Suppresses the Aggregation of Misfolded Protein in Neurodegenerative Disease

H. Ren, Liang Zhou, Hongfeng Wang, 2014, Molecular Neurobiology.

Induction of COX-2-PGE2 synthesis by activation of the MAPK/ERK pathway contributes to neuronal death triggered by TDP-43-depleted microglia

H. Ren, L. Zheng, H. Yang, 2015, Cell Death and Disease.

Parkin represses 6-hydroxydopamine-induced apoptosis via stabilizing scaffold protein p62 in PC12 cells

F. Gao, H. Ren, X. Hou, 2015, Acta Pharmacologica Sinica.

Regulation of autophagic flux by CHIP

H. Ren, Dong Chen, Hongfeng Wang, 2015, Neuroscience Bulletin.

The tumor suppressor p53 regulates autophagosomal and lysosomal biogenesis in lung cancer cells by targeting transcription factor EB.

Y. Xing, M. Shi, B. Qian, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Targeted to neuronal organelles for CNS drug development.

Xuechu Zhen, Z. Ying, Ningning Li, 2023, Advanced drug delivery reviews.

UBQLN2 and HSP70 participate in Parkin‐mediated mitophagy by facilitating outer mitochondrial membrane rupture

J. Prehn, K. Tam, H. Dussmann, 2023, EMBO reports.

Exon-intron boundary inhibits m6A deposition, enabling m6A distribution hallmark, longer mRNA half-life and flexible protein coding

Shengdong Ke, Hongfeng Wang, Z. Ying, 2023, Nature communications.

Dynasore Suppresses mTORC1 Activity and Induces Autophagy to Regulate the Clearance of Protein Aggregates in Neurodegenerative Diseases

Hongfeng Wang, Z. Ying, Li Zhang, 2019, Neurotoxicity Research.

Chlorpromazine affects autophagy in association with altered Rag GTPase–mTORC1–TFEB signaling

Hongfeng Wang, Z. Ying, Ningning Li, 2023, Frontiers in cell and developmental biology.

TDP‐43 loss of function increases TFEB activity and blocks autophagosome–lysosome fusion

F. Gao, H. Ren, Guanghui Wang, 2015, The EMBO journal.

Dynasore Suppresses mTORC1 Activity and Induces Autophagy to Regulate the Clearance of Protein Aggregates in Neurodegenerative Diseases

Hongfeng Wang, Z. Ying, Li Zhang, 2019, Neurotoxicity Research.

TARDBP/TDP-43 regulates autophagy in both MTORC1-dependent and MTORC1-independent manners

Guanghui Wang, Hongfeng Wang, Z. Ying, 2016, Autophagy.

Loss of TDP-43 Inhibits Amyotrophic Lateral Sclerosis-Linked Mutant SOD1 Aggresome Formation in an HDAC6-Dependent Manner.

Guanghui Wang, Hongfeng Wang, Z. Ying, 2015, Journal of Alzheimer's disease : JAD.

Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation.

Guanghui Wang, Xiaodong Zhu, Jia-wei Zhou, 2009, Human molecular genetics.

Pre-mRNA splicing inhibits m6A deposition, allowing longer mRNA half-life and flexible protein coding

Shengdong Ke, Hongfeng Wang, Z. Ying, 2022, bioRxiv.

ALS-linked C9orf72 dipeptide repeats inhibit starvation-induced autophagy through modulating BCL2–BECN1 interaction

Hongfeng Wang, Z. Ying, Ningning Li, 2024, Acta pharmaceutica Sinica. B.