Shuhei Kawamura

发表

Synthesis and pharmacological evaluation of nucleoside prodrugs designed to target siderophore biosynthesis in Mycobacterium tuberculosis.

C. Aldrich, R. Remmel, Surendra Dawadi, 2016, Bioorganic & medicinal chemistry.

A general alkyl-alkyl cross-coupling enabled by redox-active esters and alkylzinc reagents

Martin D. Eastgate, P. Baran, L. Malins, 2016, Science.

Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds.

X. Fradera, Haiyan Xu, M. Bittinger, 2021, ACS medicinal chemistry letters.

Allosteric Modulation of Protein Arginine Methyltransferase 5 (PRMT5).

M. Altman, Haiyan Xu, P. Siliphaivanh, 2020, ACS medicinal chemistry letters.

Design and synthesis of unprecedented 9- and 10-membered cyclonucleosides with PRMT5 inhibitory activity.

M. Altman, Christopher Sondey, J. Saurí, 2022, Bioorganic & medicinal chemistry.

Development of a new class of proteasome inhibitors with an epoxyketone warhead: Rational hybridization of non-peptidic belactosin derivatives and peptide epoxyketones.

S. Shuto, A. Asai, Y. Unno, 2014, Bioorganic & medicinal chemistry.

Investigation of the noncovalent binding mode of covalent proteasome inhibitors around the transition state by combined use of cyclopropylic strain-based conformational restriction and computational modeling.

T. Hirokawa, S. Shuto, T. Kameda, 2013, Journal of medicinal chemistry.

Practical Ni-Catalyzed Aryl–Alkyl Cross-Coupling of Secondary Redox-Active Esters

Phil S. Baran, Martin D. Eastgate, Tian Qin, 2016, Journal of the American Chemical Society.

Practical Ni-Catalyzed Aryl-Alkyl Cross-Coupling of Secondary Redox-Active Esters.

Martin D. Eastgate, P. Baran, Chung-Mao Pan, 2016 .

Design and synthesis of the stabilized analogs of belactosin A with the unnatural cis-cyclopropane structure.

S. Shuto, A. Asai, Y. Unno, 2013, Organic & biomolecular chemistry.

Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates.

S. Shuto, A. Asai, Y. Unno, 2014, Journal of medicinal chemistry.

Simple sulfinate synthesis enables C-H trifluoromethylcyclopropanation.

P. Baran, M. Collins, Jason Ge, 2014, Angewandte Chemie.

A General Alkyl‐Alkyl Cross‐Coupling Enabled by Redox‐Active Esters and Alkylzinc Reagents.

Phil S. Baran, Martin D. Eastgate, Tian Qin, 2016 .

Cyclopropane-based conformational restriction of GABA by a stereochemical diversity-oriented strategy: identification of an efficient lead for potent inhibitors of GABA transports.

S. Shuto, S. Yamada, E. Masuda, 2013, Bioorganic & medicinal chemistry.

Potent proteasome inhibitors derived from the unnatural cis-cyclopropane isomer of Belactosin A: synthesis, biological activity, and mode of action.

S. Shuto, M. Groll, A. Asai, 2013, Journal of medicinal chemistry.

Nineteen-Step Total Synthesis of (+)-Phorbol

P. Baran, J. Felding, Shuhei Kawamura, 2016, Nature.

Ligand-Phospholipid Conjugation: A Versatile Strategy for Developing Long-Acting Ligands That Bind to Membrane Proteins by Restricting the Subcellular Localization of the Ligand.

T. Hirokawa, S. Shuto, S. Yamada, 2018, Journal of medicinal chemistry.

Influence of a plasma-treated nutrient solution containing 2,4-dichlorobenzoic acid on the growth of cucumber in a hydroponic system

K. Takaki, Katsuyuki Takahashi, Shuhei Kawamura, 2021 .

The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer.

Ryan V. Quiroz, Daniel S Spellman, Haiyan Xu, 2021, Journal of medicinal chemistry.

Rational hopping of a peptidic scaffold into non-peptidic scaffolds: structurally novel potent proteasome inhibitors derived from a natural product, belactosin A.

T. Hirokawa, S. Shuto, A. Asai, 2014, Chemical communications.

Identification of Potent Reverse Indazole Inhibitors for HPK1.

X. Fradera, Haiyan Xu, M. Bittinger, 2021, ACS medicinal chemistry letters.

Design and synthesis of the stabilized analogs of belactosin A with the unnatural cis-cyclopropane structure.

S. Shuto, A. Asai, Y. Unno, 2013, Organic & biomolecular chemistry.