R. Robb

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Molecular cloning and expression of cDNAs for the human interleukin-2 receptor

G. Crabtree, T. Waldmann, W. Leonard, 1984, Nature.

In vivo administration of purified human interleukin 2. I. Half-life and immunologic effects of the Jurkat cell line-derived interleukin 2.

S. Rosenberg, M. Lotze, S. Sharrow, 1985, Journal of immunology.

Regulation of interleukin 2 (IL2) receptor expression: IL 2 as an inducing signal for the expression of its own receptor on a murine T helper cell line

A. Dautry‐Varsat, G. Bismuth, J. Thèze, 1985, European journal of immunology.

Internalization and nuclear localization of interleukin 1 are not sufficient for function.

A. Heguy, C. Baldari, M. Melli, 1991, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Liposomal formulation of a self lymphoma antigen induces potent protective antitumor immunity.

M. C. Popescu, L. Kwak, R. Pennington, 1998, Journal of immunology.

Human interleukin 2.

R. Robb, 1985, Methods in enzymology.

Direct demonstration of the identity of T cell growth factor binding protein and the Tac antigen

W. Greene, R. Robb, 1983, The Journal of experimental medicine.

Posttranslational modification of human T-cell growth factor.

W. DeGrado, H. Morris, M. Panico, 1983, Biochemical and biophysical research communications.

An ELISA-based assay for quantitation of human interleukin 2.

R. Robb, L. O. Gehman, 1984, Journal of immunological methods.

Human T-cell growth factor: purification biochemical characterization, and interaction with a cellular receptor.

R. Robb, 1982, Immunobiology.

Quantitation, Specificity, and Biological Relevance*

Kendall A. Smith, A. Munck, R. Robb, 1981 .

The murine IL 2 receptor. I. Monoclonal antibodies that define distinct functional epitopes on activated T cells and react with activated B cells.

E. Shevach, T. Malek, R. Robb, 1984, Journal of immunology.

Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex.

E. Shevach, T. Malek, R. Robb, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Human Autologous Tumor-Specific T-Cell Responses Induced by Liposomal Delivery of a Lymphoma Antigen

M. C. Popescu, E. Jaffe, L. Kwak, 2004, Clinical Cancer Research.

The human receptor for T-cell growth factor. Evidence for variable post-translational processing, phosphorylation, sulfation, and the ability of precursor forms of the receptor to bind T-cell growth factor.

T. Waldmann, W. Leonard, W. Greene, 1985, The Journal of biological chemistry.

The systemic administration of purified interleukin 2 enhances the ability of sensitized murine lymphocytes to cure a disseminated syngeneic lymphoma.

A. Chang, S. Rosenberg, M. Lotze, 1984, Journal of immunology.

Systemic administration of interleukin-2 in humans.

S. Rosenberg, M. Lotze, S. Sharrow, 1984, Journal of biological response modifiers.

Complete amino acid sequence of a papain-solubilized human histocompatibility antigen HLA-B7. 1. Isolation and amino acid composition of fragments and of tryptic and chymotryptic peptides.

H. Orr, J. Strominger, D. Mann, 1979, Biochemistry.

Localization of the disulfide bridges of human histocompatibility antigens.

J. Strominger, R. Robb, C. Terhorst, 1979, Molecular Immunology.

Rabbit anti-HL-A2 sera.

J. Strominger, R. Humphreys, R. Robb, 1975, Transplantation.

Papain-solubilized HL-A antigens. Chromatographic and electrophoretic studies of the two subunits from different specificities.

P. Cresswell, J. Strominger, M. Turner, 1974, The Journal of biological chemistry.

Submit and disulfide structure of monomeric and dimeric forms of detergent-soluble HLA antigens.

J. Strominger, T. Springer, R. Robb, 1977, The Journal of biological chemistry.

A novel proteoliposomal vaccine elicits potent antitumor immunity in mice.

M. C. Popescu, L. Kwak, R. Pennington, 2007, Blood.

A novel proteoliposomal vaccine induces antitumor immunity against follicular lymphoma.

M. C. Popescu, L. Kwak, Seung-Tae Lee, 2007, Blood.

Characterization of the human receptor for T-cell growth factor.

T. Waldmann, W. Leonard, W. Greene, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Interleukin 2: the molecule and its function.

R. Robb, 1984, Immunology today.

Purification and partial sequence analysis of human T-cell growth factor.

V. Chowdhry, R. Robb, R. Kutny, 1983, Proceedings of the National Academy of Sciences of the United States of America.

In situ vaccination against a non-immunogenic tumour using intratumoural injections of liposomal interleukin 2.

M. C. Popescu, R. Robb, M. Neville, 2001, Cytokine.

Blockade of the interleukin-2 receptor by anti-Tac antibody: inhibition of human lymphocyte activation.

T. Waldmann, W. Leonard, W. Greene, 1983, Journal of immunology.

HepG2 cells predominantly express the type II interleukin 1 receptor (biochemical and molecular characterization of the IL-1 receptor).

W. L. Wong, R. Horuk, J. Giri, 1992, Cytokine.

Identification of a membrane antigen that is distinct from the interleukin 2 receptor and that may be required for interleukin 2-driven proliferative responses.

E. Shevach, T. Malek, R. Robb, 1983, Journal of immunology.

Lymphoma Antigen Induces Potent Protective Cutting Edge: Liposomal Formulation of a Self

M. C. Popescu, L. Kwak, R. Pennington, 1998 .

Interleukin-2 receptors on activated malignant and normal B-cells.

T. Waldmann, S. Korsmeyer, W. Leonard, 1984, Current topics in microbiology and immunology.

Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells

W. Leonard, W. Greene, J. Depper, 1985, Journal of Experimental Medicine.

Proliferation of T lymphocytes in response to interleukin 2 varies with their state of activation.

J. Ashwell, T. Malek, R. Robb, 1986, Journal of Immunology.

Purification, Interaction with a Cellular Receptor, and in Vitro Synthesis

R. Robb, Yuan Lin, 1984 .

The suppressive effect of gangliosides upon IL 2-dependent proliferation as a function of inhibition of IL 2-receptor association.

R. Robb, 1986, Journal of immunology.

Identification of a direct interaction between interleukin 2 and the p64 interleukin 2 receptor gamma chain.

T. Leary, S. Voss, P. Sondel, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Mechanism of action of Cyclosporin A: inhibition of lymphokine secretion studied with antigen-stimulated T cell hybridomas.

A. Chang, S. Rosenberg, R. Robb, 1984, Journal of immunology.

Regulation of IFN-gamma induction in human peripheral blood cells by exogenous and endogenously produced interleukin 2.

D. Siegel, J. Vilček, D. Henriksen-DeStefano, 1985, Journal of immunology.

Interleukin-2-induced small unilamellar vesicle coalescence.

M. C. Popescu, J. Mason, M. Batenjany, 2001, Biochimica et biophysica acta.

Induction of high affinity IL 2 receptors on B cells responding to anti-Ig and T cell-derived helper factors.

R. Stout, D. Parker, R. Robb, 1985, Journal of immunology.

Affinity-purified interleukin 2 induces proliferation of large but not small B cells.

F. Finkelman, C. Thompson, M. Schaefer, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Stimulation of immunoglobulin secretion in human B lymphocytes as a direct effect of high concentrations of IL 2.

T. Boone, R. Mertelsmann, K. Welte, 1984, Journal of immunology.

High and low affinity receptors for interleukin 2: implications of pronase, phorbol ester, and cell membrane studies upon the basis for differential ligand affinities.

R. Robb, C. M. Rusk, 1986, Journal of immunology.

Internalization of interleukin 2 is mediated by the beta chain of the high-affinity interleukin 2 receptor

W. Greene, R. Robb, 1987, The Journal of experimental medicine.

Conversion of low-affinity interleukin 2 receptors to a high-affinity state following fusion of cell membranes.

R. Robb, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Structure-function relationships for the IL 2-receptor system. I. Localization of a receptor binding site on IL 2.

R. Robb, L. Kuo, 1986, Journal of immunology.

Expression of interleukin 2 receptors on activated human B cells

T. Waldmann, S. Korsmeyer, W. Leonard, 1984, The Journal of experimental medicine.

Structure-function relationships for high and low-affinity interleukin 2 receptors.

R. Robb, 1989, Advances in experimental medicine and biology.

Structure—Function Relations for the Interleukin-2 Receptor

R. Robb, 1988 .

The Human High Affinity Interleukin-2 Receptor

W. Greene, J. Kehrl, M. Dukovich, 1987 .

Lymphokine-activated killer cell phenomenon. III. Evidence that IL-2 is sufficient for direct activation of peripheral blood lymphocytes into lymphokine-activated killer cells

J. Roth, S. Rosenberg, E. Grimm, 1983, The Journal of experimental medicine.

Molecular Analysis of the Human Interleukin-2 Receptor

G. Crabtree, T. Waldmann, W. Leonard, 1985 .

Molecular cloning of cDNA for the human interleukin-2 receptor.

G. Crabtree, T. Waldmann, W. Greene, 1985, Haematology and blood transfusion.

Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen

W. Greene, R. Robb, C. M. Rusk, 1984, The Journal of experimental medicine.

Effect of wheat germ agglutinin on the interleukin pathway of human T lymphocyte activation.

P. Nowell, W. Greene, John Calvin Reed, 1985, Journal of immunology.

Structure-function relationships for the interleukin 2 receptor: location of ligand and antibody binding sites on the Tac receptor chain by mutational analysis.

M. Neeper, R J Robb, C M Rusk, 1988, Proceedings of the National Academy of Sciences of the United States of America.

A comparison of biodistribution of liposomal and soluble IL-2 by a new method based on time-resolved fluorometry of europium.

M. C. Popescu, R. Robb, L. Boni, 2000, Cytokine.

Biopharmaceutics of liposomal interleukin 2, oncolipin.

M. C. Popescu, R. Robb, L. Boni, 2000, Cytokine.

Analysis of prostaglandin E2 effect on T lymphocyte activation. Abrogation of prostaglandin E2 inhibitory effect by the tumor promotor 12.0 tetradecanoyl phorbol-13 acetate.

K. Welte, S. Chouaib, R. Robb, 1987, The Journal of clinical investigation.

Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors.

W. Greene, J. Yodoi, R. Robb, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of the interleukin 2 receptors (IL-2R) expressed on human natural killer cells activated in vivo by IL-2: association of the p64 IL-2R gamma chain with the IL-2R beta chain in functional intermediate-affinity IL-2R

S. Voss, P. Sondel, R. Robb, 1992, The Journal of experimental medicine.

Increased expression of the interleukin 2 (IL-2) receptor beta chain (p70) on CD56+ natural killer cells after in vivo IL-2 therapy: p70 expression does not alone predict the level of intermediate affinity IL- 2 binding

K. Sugamura, M. Tsudo, S. Voss, 1990, The Journal of experimental medicine.

Receptors for T-cell growth factor: structure, function and expression on normal and neoplastic cells.

W. Greene, R. Robb, 1985, Contemporary topics in molecular immunology.

Structure-function relationships for the IL 2-receptor system. IV. Analysis of the sequence and ligand-binding properties of soluble Tac protein.

R. Robb, R. Kutny, 1987, Journal of immunology.

Structure-function relationships for the IL 2-receptor system. II. Localization of an IL 2 binding site on high and low affinity receptors.

R. Robb, C. M. Rusk, L. Kuo, 1986, Journal of immunology.

Sequence of the COOH-terminal hydrophilic region of histocompatibility antigens HLA-A2 and HLA-B7.

J. Strominger, R. Robb, C. Terhorst, 1978, The Journal of biological chemistry.

In vivo administration of purified Jurkat-derived interleukin 2 in mice.

E. Jaffe, R. Braziel, S. Rosenberg, 1984, Cancer research.

Retention of biological activity following radioiodination of human interleukin 2: comparison with biosynthetically labeled growth factor in receptor binding assays.

R. Robb, P. C. Mayer, R. Garlick, 1985, Journal of immunological methods.

The heavy chain of human histocompatibility antigen HLA-B7 contains an immunoglobulin-like region

D. Lancet, H. Orr, J. Strominger, 1979, Nature.

Antigen/mitogen induced cytolytic activity and IL-2 secretion in memory-like CTL-hybridomas.

S. Rosenberg, G. Berke, R. Robb, 1985, Advances in experimental medicine and biology.

Human Autologous Tumor-Specific T-Cell Responses Induced by Liposome Encapsulated Lymphoma Membrane Proteins.

M. C. Popescu, L. Kwak, S. Neelapu, 2004 .

Phorbol diester induces expression of Tac antigen on human acute T lymphocytic leukemic cells.

T. Waldmann, W. Leonard, W. Greene, 1984, Journal of immunology.

The effect of cholesterol in a liposomal Muc1 vaccine.

M. C. Popescu, M. Batenjany, R. Robb, 2001, Biochimica et biophysica acta.

Effect of cyclosporin A and dexamethasone on interleukin 2 receptor gene expression.

P. Nowell, John Calvin Reed, J. Alpers, 1986, Journal of immunology.

Quantitative characterization of the intrinsic ligand-binding affinity of the interleukin 2 receptor beta chain and its modulation by the alpha chain and a second affinity-modulating element.

R. Robb, B. Freimark, G. Ringheim, 1991, Lymphokine and cytokine research.

Amino acid sequence and post-translational modification of human interleukin 2.

H. Morris, M. Panico, V. Chowdhry, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Induction of interleukin 2 production in the gibbon ape T cell line MLA 144.

Y. Lin, R. Robb, 1985, Lymphokine research.

Heterogeneity of human T-cell growth factor(s) due to variable glycosylation.

Kendall A. Smith, K. Smith, R. Robb, 1981, Molecular immunology.

Structure function relationships for the IL 2 receptor system. III. Tac protein missing amino acids 102 to 173 (exon 4) is unable to bind IL 2: detection of spliced protein after L cell transfection.

M. Kiefer, M. Neeper, R. Robb, 1987, Journal of immunology.