J. Zajac

发表

Platinum (IV) Derivatives with Cinnamate Axial Ligands as Potent Agents Against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells

V. Brabec, J. Kašpárková, J. Zajac, 2020, Angewandte Chemie.

Platinum (IV) Derivatives with Cinnamate Axial Ligands Are Potent Agents Against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells.

V. Brabec, J. Kašpárková, J. Zajac, 2019, Angewandte Chemie.

A Multi‐action Pt IV Conjugate with Oleate and Cinnamate Ligands Targets Human Epithelial Growth Factor Receptor HER2 in Aggressive Breast Cancer Cells

V. Brabec, J. Kašpárková, H. Kostrhunova, 2020, Angewandte Chemie.

A New Multi-action Pt(IV) Conjugate with Oleate and Cinnamate Ligands Targets Human Epithelial Growth Factor Receptor HER2 in Aggressive Breast Cancer Cells.

V. Brabec, J. Kašpárková, H. Kostrhunova, 2020, Angewandte Chemie.

New Acridine Thiourea Gold(I) Anticancer Agents: Targeting the Nucleus and Inhibiting Vasculogenic Mimicry.

V. Brabec, H. Kostrhunova, A. Zamora, 2017, ACS chemical biology.

Highly potent extranuclear-targeted luminescent iridium(iii) antitumor agents containing benzimidazole-based ligands with a handle for functionalization.

V. Brabec, C. Janiak, S. A. Perez, 2016, Chemical communications.

Discovery of selective, antimetastatic and anti-cancer stem cell metallohelices via post-assembly modification† †Electronic supplementary information (ESI) available: Data created during this study are openly available from the University of Warwick Research Archive Portal (WRAP) (http://wrap.warwic

V. Brabec, L. Young, R. Phillips, 2019, Chemical science.

Influence of the binding of reduced NAMI-A to human serum albumin on the pharmacokinetics and biological activity.

V. Brabec, A. Bergamo, G. Sava, 2015, Dalton transactions.

Novel Antitumor Platinum(II) Conjugates Containing the Nonsteroidal Anti-inflammatory Agent Diclofenac: Synthesis and Dual Mechanisms of Antiproliferative Effects.

V. Brabec, G. Natile, J. Kašpárková, 2017, Inorganic chemistry.

A Subset of New Platinum Antitumor Agents Kills Cells by a Multimodal Mechanism of Action Also Involving Changes in the Organization of the Microtubule Cytoskeleton.

V. Brabec, J. Kašpárková, J. Aldrich-Wright, 2019, Journal of medicinal chemistry.

Simultaneous delivery of olaparib and carboplatin in PEGylated liposomes imparts this drug combination hypersensitivity and selectivity for breast tumor cells

V. Brabec, J. Kašpárková, J. Zajac, 2018, Oncotarget.

Enhancing Tumor Cell Response to Chemotherapy through the Targeted Delivery of Platinum Drugs Mediated by Highly Stable, Multifunctional Carboxymethylcellulose-Coated Magnetic Nanoparticles.

V. Brabec, J. Kašpárková, M. Petr, 2016, Chemistry.

Potentiation of mitochondrial dysfunction in tumor cells by conjugates of metabolic modulator dichloroacetate with a Pt(IV) derivative of oxaliplatin.

V. Brabec, J. Kašpárková, D. Gibson, 2016, Journal of inorganic biochemistry.