K. Shirneshan

发表

Comprehensive analysis of isolated der(1;7)(q10;p10) in a large international homogenous cohort of patients with myelodysplastic syndromes

F. Solé, K. Götze, N. Kröger, 2019, Genes, chromosomes & cancer.

Frequency and prognostic impact of casein kinase 1A1 mutations in MDS patients with deletion of chromosome 5q

K. Döhner, M. Heuser, F. Thol, 2015, Leukemia.

Impact of somatic mutations in myelodysplastic patients with isolated partial or total loss of chromosome 7

F. Solé, G. Mufti, J. Cervera, 2020, Leukemia.

Peripheral blood cytogenetics allows treatment monitoring and early identification of treatment failure to lenalidomide in MDS patients: results of the LE-MON-5 trial

R. Schlenk, A. Ganser, T. Brümmendorf, 2017, Annals of Hematology.

Results of a multicenter prospective phase II trial investigating the safety and efficacy of lenalidomide in patients with myelodysplastic syndromes with isolated del(5q) (LE-MON 5)

R. Schlenk, A. Ganser, K. Götze, 2016, Leukemia.

Validation of cytogenetic risk groups according to International Prognostic Scoring Systems by peripheral blood CD34+FISH: results from a German diagnostic study in comparison with an international control group

F. Solé, M. L. Le Beau, T. Brümmendorf, 2015, Haematologica.

New data shed light on Y‐loss‐related pathogenesis in myelodysplastic syndromes

S. Machherndl-Spandl, K. Jung, D. Kämpfe, 2015, Genes, chromosomes & cancer.

Inactivation of insulin-like factor 6 disrupts the progression of spermatogenesis at late meiotic prophase.

I. Adham, W. Engel, A. Meinhardt, 2009, Endocrinology.

Targeted deep sequencing of CD34+ cells from peripheral blood can reproduce bone marrow molecular profile in myelodysplastic syndromes

F. Solé, L. Trümper, V. Adema, 2018, American journal of hematology.

Directed overexpression of insulin in Leydig cells causes a progressive loss of germ cells

S. Binder, I. Adham, W. Engel, 2008, Molecular and Cellular Endocrinology.

Molecular cytogenetic analysis of a de novo balanced X;autosome translocation: Evidence for predominant inactivation of the derivative X chromosome in a girl with multiple malformations

S. Bohlander, H. Kehrer-Sawatzki, B. Zoll, 2004, American journal of medical genetics. Part A.

FISH analysis of circulating CD34+ cells as a new tool for genetic monitoring in MDS: verification of the method and application to 27 MDS patients.

L. Trümper, K. Jung, D. Haase, 2010, Leukemia research.

Sequential Combination of Azacitidine and Lenalidomide Can Target the TP53 -Mutated Clone in Del(5q) Higher-Risk Myelodysplastic Syndromes

K. Götze, W. Hofmann, U. Germing, 2012 .

Proof of Y-Loss As Clonal Abnormality in MDS by Comparative Analysis of CD34+ and CD3+ Peripheral Blood Cells,

U. Platzbecker, D. Kämpfe, D. Haase, 2011 .

Prevalence, clonal dynamics and clinical impact of TP53 mutations in patients with myelodysplastic syndrome with isolated deletion (5q) treated with lenalidomide: results from a prospective multicenter study of the german MDS study group (GMDS)

R. Schlenk, A. Ganser, T. Haferlach, 2016, Leukemia.

Safety and Efficacy of a Combination of 5-Azacitidine Followed by Lenalidomide in High-Risk MDS or AML Patients with Del(5q) Cytogenetic Abnormalities – Results of the “AZALE” Trial,

K. Götze, W. Hofmann, U. Germing, 2011 .

INSL5-deficient mice display an alteration in glucose homeostasis and an impaired fertility.

I. Adham, B. Mohamed, T. Klonisch, 2012, Endocrinology.

Primary osteomyelofibrosis and an XX‐male genotype

J. Bäsecke, D. Haase, J. Schanz, 2015, European journal of haematology.

Impact of PPM1D mutations in patients with myelodysplastic syndrome and deletion of chromosome 5q

K. Döhner, M. Heuser, F. Thol, 2021, American journal of hematology.

Mutational and immunogenetic landscape of HCV-associated B-cell lymphoproliferative disorders

K. Döhner, M. Heuser, F. Thol, 2021 .

Comparative methylation profiles and telomerase biology of mouse multipotent adult germline stem cells and embryonic stem cells.

T. Haaf, W. Engel, U. Zechner, 2009, Molecular human reproduction.

MDS1 and EVI1 complex locus (MECOM): a novel candidate gene for hereditary hematological malignancies

D. Steinemann, T. Illig, G. Wulf, 2017, Haematologica.

Cytogenetics of MDS

C. Steidl, D. Haase, J. Schanz, 2011 .

Prenatal diagnosis of Roberts syndrome and detection of an ESCO2 frameshift mutation in a Pakistani family

P. Wieacker, K. Shirneshan, S. Schulz, 2008, Prenatal diagnosis.

Molecular cytogenetic monitoring from CD34+ peripheral blood cells in myelodysplastic syndromes: first results from a prospective multicenter German diagnostic study.

R. Schlenk, T. Brümmendorf, K. Götze, 2013, Leukemia research.

Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression data

R. Spang, W. Klapper, M. Szczepanowski, 2016, Oncotarget.

Spongiform encephalopathy in siblings with no evidence of protease-resistant prion protein or a mutation in the prion protein gene

M. Faist, K. Kallenberg, D. Varges, 2013, Journal of Neurology.

Cytogenetic peripheral blood monitoring in azacitidine treated patients with high-risk MDS/sAML: A monocentric real-world experience.

A. Leha, D. Haase, J. Schanz, 2022, Leukemia research.

Influence of total genomic alteration and chromosomal fragmentation on response to a combination of azacitidine and lenalidomide in a cohort of patients with very high risk MDS.

U. Platzbecker, G. Salinas-Riester, D. Haase, 2015, Leukemia research.

Detailed analysis of clonal evolution and cytogenetic evolution patterns in patients with myelodysplastic syndromes (MDS) and related myeloid disorders

C. Fonatsch, D. Haase, J. Schanz, 2018, Blood Cancer Journal.

Detailed analysis of clonal evolution and cytogenetic evolution patterns in patients with myelodysplastic syndromes (MDS) and related myeloid disorders

C. Fonatsch, D. Haase, J. Schanz, 2018, Blood Cancer Journal.

Bivalent promoter marks and a latent enhancer may prime the leukaemia oncogene LMO1 for ectopic expression in T-cell leukaemia

B. Göttgens, J. Schütte, F. Calero-Nieto, 2013, Leukemia.

Sequential combination of azacitidine and lenalidomide in del(5q) higher-risk myelodysplastic syndromes or acute myeloid leukemia: a phase I study

K. Götze, A. Giagounidis, U. Platzbecker, 2013, Leukemia.

New data shed light on Y‐loss‐related pathogenesis in myelodysplastic syndromes

S. Machherndl-Spandl, K. Jung, D. Kämpfe, 2015, Genes, chromosomes & cancer.

Regions of homozygosity confer a worse prognostic impact in myelodysplastic syndrome with normal karyotype

L. Arenillas, F. Solé, L. Shih, 2023, EJHaem.