A. Thalhammer

发表

Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)

P. Ratcliffe, E. Hammond, C. Schofield, 2011, PloS one.

OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

Rachelle S. Singleton, P. Ratcliffe, M. Coleman, 2014, Proceedings of the National Academy of Sciences.

Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases.

D. Harding, C. Schofield, T. Claridge, 2011, Nature chemistry.

Development and Application of a Fluoride‐Detection‐Based Fluorescence Assay for γ‐Butyrobetaine Hydroxylase

U. Oppermann, C. Schofield, G. Kochan, 2012, Chembiochem : a European journal of chemical biology.

Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates.

T. Heightman, C. Schofield, A. Tumber, 2011, Organic & biomolecular chemistry.

Improved synthesis of 5-hydroxymethyl-2'-deoxycytidine phosphoramidite using a 2'-deoxyuridine to 2'-deoxycytidine conversion without temporary protecting groups.

T. Brown, C. Schofield, A. El-Sagheer, 2011, Bioorganic & medicinal chemistry letters.

Inhibiteurs d’histone lysine déméthylase

C. Schofield, M. McDonough, N. R. Rose, 2009 .

Triflic anhydride-mediated synthesis of oxazoles

C. Schofield, J. Mecinović, A. Thalhammer, 2009 .

Role of the jelly-roll fold in substrate binding by 2-oxoglutarate oxygenases.

Michael A McDonough, Christopher J Schofield, C. Schofield, 2012, Current opinion in structural biology.

Structural insights into how 5-hydroxymethylation influences transcription factor binding.

Tom Brown, Michael A McDonough, Christopher J Schofield, 2014, Chemical communications.

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans.

C. Robinson, P. Ratcliffe, M. Coleman, 2012, Nature chemical biology.

Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy

P. Ratcliffe, M. Mackeen, B. Kessler, 2014, Proceedings of the National Academy of Sciences.

Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(II).

C. Schofield, J. Mecinović, N. R. Rose, 2009, Chemical communications.

Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth

P. Ratcliffe, C. Schofield, M. Melani, 2014, Proceedings of the National Academy of Sciences.

Hydroxylation of methylated CpG dinucleotides reverses stabilisation of DNA duplexes by cytosine 5-methylation.

Tom Brown, Christopher J Schofield, T. Brown, 2011, Chemical communications.

Synthesis of Novel Pyridine‐Carboxylates as Small‐Molecule Inhibitors of Human Aspartate/Asparagine‐β‐Hydroxylase

E. Salah, C. Schofield, A. Tumber, 2020, ChemMedChem.

Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases

C. Schofield, M. McDonough, W. Aik, 2015, Structure.

Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion.

P. Ratcliffe, M. Mackeen, C. Schofield, 2013, Organic & biomolecular chemistry.

The potential of 2-oxoglutarate oxygenases acting on nucleic acids as therapeutic targets

Eleanor A. L. Bagg, C. Schofield, W. Aik, 2012 .

Quantitative modeling of triacylglycerol homeostasis in yeast – metabolic requirement for lipolysis to promote membrane lipid synthesis and cellular growth

Christian Jungreuthmayer, Klaus Natter, Jürgen Zanghellini, 2008, The FEBS journal.

Fluoromethylated derivatives of carnitine biosynthesis intermediates--synthesis and applications.

C. Schofield, G. Kochan, T. Claridge, 2014, Chemical communications.

Fluoromethylated derivatives of carnitine biosynthesis intermediates--synthesis and applications.

C. Schofield, G. Kochan, T. Claridge, 2014, Chemical communications.

Photoactivable peptides for identifying enzyme-substrate and protein-protein interactions.

A. Mai, P. Ratcliffe, B. Kessler, 2011, Chemical communications.