N. Harada

发表

Antithrombin inhibits lipopolysaccharide‐induced tumor necrosis factor‐α production by monocytes in vitro through inhibition of Egr‐1 expression

H. Komura, M. Uchiba, Y. Mizuochi, 2008, Journal of thrombosis and haemostasis : JTH.

Activated Neutrophils Impair Gastric Cytoprotection: Role of Neutrophil Elastase

Wenge Liu, M. Uchiba, N. Harada, 2000, Digestive Diseases and Sciences.

Activated protein C reduces stress‐induced gastric mucosal injury in rats by inhibiting the endothelial cell injury

H. Okabe, H. Isobe, N. Harada, 2004, Journal of thrombosis and haemostasis : JTH.

Antithrombin prevents stress-induced gastric mucosal injury by increasing the gastric prostacyclin level in rats.

H. Isobe, N. Harada, K. Okajima, 1999, The Journal of laboratory and clinical medicine.

Novel role of prostacyclin in stress-induced gastric mucosal lesion formation in rats.

K. Takatsuki, H. Okabe, M. Uchiba, 1997, The Journal of laboratory and clinical medicine.

Activated Protein C Reduces the Severity of Compression-Induced Spinal Cord Injury in Rats by Inhibiting Activation of Leukocytes

M. Uchiba, N. Harada, K. Okajima, 1998, The Journal of Neuroscience.

Antithrombin reduces ischemia/reperfusion injury of rat liver by increasing the hepatic level of prostacyclin.

S. Kushimoto, H. Isobe, N. Harada, 1999, Blood.

Antithrombin reduces ischemia/reperfusion-induced renal injury in rats by inhibiting leukocyte activation through promotion of prostacyclin production.

T. Noguchi, H. Isobe, M. Uchiba, 2003, Blood.

Antithrombin reduces ischemia/reperfusion-induced liver injury in rats by activation of cyclooxygenase-1

S. Kushimoto, H. Isobe, M. Uchiba, 2004, Thrombosis and Haemostasis.

Contribution of capsaicin-sensitive sensory neurons to antithrombin-induced reduction of ischemia/reperfusion-induced liver injury in rats

H. Isobe, N. Harada, K. Okajima, 2004, Thrombosis and Haemostasis.

Atrial Natriuretic Peptide Reduces Ischemia/Reperfusion-Induced Spinal Cord Injury in Rats by Enhancing Sensory Neuron Activation

M. Asano, Takayuki Saito, N. Harada, 2007, Journal of Pharmacology and Experimental Therapeutics.

Atrial natriuretic peptide reduces the ischemia/reperfusion-induced renal injury in rats by enhancing sensory neuron activation

Y. Mizuochi, N. Harada, K. Okajima, 2007, Critical Care.

Dihydrotestosterone inhibits hair growth in mice by inhibiting insulin-like growth factor-I production in dermal papillae.

N. Harada, K. Okajima, Juan Zhao, 2011, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Dietary isoflavone increases insulin-like growth factor-I production, thereby promoting hair growth in mice.

H. Kurihara, N. Nakagata, N. Harada, 2011, The Journal of nutritional biochemistry.

New Aspects of Antiinflammatory Activity of Antithrombin: Molecular Mechanism(s) and Therapeutic Implications

N. Harada, K. Okajima, 2008 .

Rebamipide Attenuates Indomethacin-Induced Gastric Mucosal Lesion Formation by Inhibiting Activation of Leukocytes in Rats

K. Takatsuki, H. Okabe, M. Uchiba, 1997, Digestive Diseases and Sciences.

Role of granulocyte elastase in indomethacin-induced gastric mucosal lesion formation in rats.

K. Takatsuki, H. Okabe, M. Uchiba, 1997, The Journal of laboratory and clinical medicine.

Antithrombin prevents reperfusion-induced hepatic apoptosis by enhancing insulin-like growth factor-I production in mice

H. Kurihara, N. Nakagata, N. Harada, 2008, Critical care medicine.

Administration of capsaicin and isoflavone promotes hair growth by increasing insulin-like growth factor-I production in mice and in humans with alopecia.

H. Kurihara, N. Nakagata, M. Arai, 2007, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

production by inhibiting leukocyte activation through promotion of prostacyclin Antithrombin reduces ischemia / reperfusion-induced renal injury in rats

T. Noguchi, H. Isobe, M. Uchiba, 2002 .

Antithrombin prevents endotoxin-induced hypotension by inhibiting the induction of nitric oxide synthase in rats.

H. Okabe, H. Isobe, M. Uchiba, 2002, Blood.

Activation of Capsaicin-Sensitive Sensory Neurons by Carvedilol, a Nonselective β-Blocker, in Spontaneous Hypertensive Rats

H. Isobe, M. Uchiba, N. Harada, 2004, Journal of Pharmacology and Experimental Therapeutics.

Stimulation of FcγRI on Primary Sensory Neurons Increases Insulin-Like Growth Factor-I Production, Thereby Reducing Reperfusion-Induced Renal Injury in Mice

H. Kurihara, N. Nakagata, N. Harada, 2010, The Journal of Immunology.

Effects of Topical Application of α-D-Glucosylglycerol on Dermal Levels of Insulin-Like Growth Factor-I in Mice and on Facial Skin Elasticity in Humans

H. Kurihara, N. Nakagata, N. Harada, 2010, Bioscience, biotechnology, and biochemistry.

Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans.

H. Kurihara, N. Nakagata, N. Harada, 2008, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

RETRACTED: Stimulation of sensory neurons by capsaicin increases tissue levels of IGF-I, thereby reducing reperfusion-induced apoptosis in mice

H. Kurihara, N. Nakagata, N. Harada, 2007, Neuropharmacology.

Contribution of sensory neurons to sex difference in the development of stress-induced gastric mucosal injury in mice.

H. Kurihara, S. Shimada, N. Nakagata, 2006, Gastroenterology.

Effects of Capsaicin and Isoflavone on Blood Pressure and Serum Levels of Insulin-Like Growth Factor-I in Normotensive and Hypertensive Volunteers with Alopecia

N. Harada, K. Okajima, 2009, Bioscience, biotechnology, and biochemistry.

Activation of sensory neurons contributes to reduce spinal cord injury in rats

S. Shimada, M. Arai, N. Harada, 2007, Neuropharmacology.

Role of sensory neuron in reduction of endotoxin-induced hypotension in rats

H. Isobe, M. Uchiba, N. Harada, 2005, Critical care medicine.

Contribution of capsaicin-sensitive sensory neurons to stress-induced increases in gastric tissue levels of prostaglandins in rats.

M. Uchiba, N. Harada, K. Okajima, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Effect of topical application of capsaicin and its related compounds on dermal insulin-like growth factor-I levels in mice and on facial skin elasticity in humans.

N. Harada, K. Okajima, 2007, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Microthrombus formation enhances tumor necrosis factor‐α production in the development of ischemia/reperfusion‐induced liver injury in rats

M. Uchiba, N. Harada, K. Okajima, 2003, Journal of thrombosis and haemostasis : JTH.

Activated Protein C Prevents Endotoxin-Induced Hypotension in Rats by Inhibiting Excessive Production of Nitric Oxide

H. Isobe, M. Uchiba, N. Harada, 2001, Circulation.

Gastric prostacyclin (PGI2) prevents stress-induced gastric mucosal injury in rats primarily by inhibiting leukocyte activation.

H. Isobe, N. Harada, K. Okajima, 1999, Prostaglandins & other lipid mediators.

Leukocyte depletion and ONO-5046, a specific inhibitor of granulocyte elastase, prevent a stress-induced decrease in gastric prostaglandin I2 in rats.

K. Takatsuki, H. Okabe, K. Tanaka, 1997, Biochemical and biophysical research communications.

Neutrophil elastase contributes to the development of ischemia-reperfusion-induced liver injury by decreasing endothelial production of prostacyclin in rats.

M. Uchiba, N. Harada, K. Okajima, 2004, American journal of physiology. Gastrointestinal and liver physiology.

Effect of capsaicin on plasma and tissue levels of insulin-like growth factor-I in spontaneously hypertensive rats.

N. Harada, K. Okajima, 2008, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Dalteparin, a low molecular weight heparin, attenuates inflammatory responses and reduces ischemia-reperfusion–induced liver injury in rats*

M. Uchiba, N. Harada, K. Okajima, 2006, Critical care medicine.

Estrogen and isoflavone attenuate stress-induced gastric mucosal injury by inhibiting decreases in gastric tissue levels of CGRP in ovariectomized rats.

N. Harada, K. Okajima, N. Shimozawa, 2007, American journal of physiology. Gastrointestinal and liver physiology.

Role of Microthrombus Formation in the Development of Ischemia/Reperfusion-induced Liver Injury in Rats

S. Kushimoto, M. Uchiba, N. Harada, 2002, Thrombosis and Haemostasis.

Gabexate mesilate, a synthetic protease inhibitor, reduces ischemia/reperfusion injury of rat liver by inhibiting leukocyte activation.

S. Kushimoto, N. Harada, K. Okajima, 1999, Critical care medicine.

Neutrophil elastase contributes to the development of ischemia/reperfusion-induced liver injury by decreasing the production of insulin-like growth factor-I in rats.

H. Takeyama, N. Harada, K. Okajima, 2010, Translational research : the journal of laboratory and clinical medicine.

Insulin-like growth factor-I reduces stress-induced gastric mucosal injury by inhibiting neutrophil activation in mice.

K. Sobue, N. Harada, H. Katsuya, 2009, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Reduction of spinal cord injury by administration of iloprost, a stable prostacyclin analog.

K. Takatsuki, H. Okabe, M. Uchiba, 1997, Journal of neurosurgery.

RECOMBINANT THROMBOMODULIN PREVENTS ENDOTOXIN‐INDUCED LUNG INJURY IN RATS BY INHIBITING LEUKOCYTE ACTIVATION: 227

H. Isobe, M. Uchiba, N. Harada, 1996 .

Inhibition of lipopolysaccharide-induced tissue factor expression in monocytes by urinary trypsin inhibitor in vitro and in vivo

H. Okabe, H. Isobe, M. Uchiba, 2005, Thrombosis and Haemostasis.

Urinary trypsin inhibitor reduces LPS-induced hypotension by suppressing tumor necrosis factor-alpha production through inhibition of Egr-1 expression.

H. Okabe, H. Isobe, M. Uchiba, 2005, American journal of physiology. Heart and circulatory physiology.

Inhibition of tumor necrosis factor-α production by urinary trypsin inhibitor

H. Isobe, M. Uchiba, N. Harada, 2003 .

Metformin, an Antidiabetic Agent, Suppresses the Production of Tumor Necrosis Factor and Tissue Factor by Inhibiting Early Growth Response Factor-1 Expression in Human Monocytes in Vitro

H. Komura, M. Uchiba, Y. Mizuochi, 2010, Journal of Pharmacology and Experimental Therapeutics.

Carvedilol, a nonselective beta-blocker, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro.

H. Komura, M. Uchiba, Y. Mizuochi, 2007, Translational research : the journal of laboratory and clinical medicine.

ROLE OF NEUTROPHIL ELASTASE IN DEVELOPMENT OF PULMONARY VASCULAR INJURY AND SEPTIC SHOCK IN RATS

H. Isobe, N. Harada, K. Okajima, 2008, Shock.

Ischemia/reperfusion-induced increase in the hepatic level of prostacyclin is mainly mediated by activation of capsaicin-sensitive sensory neurons in rats.

M. Uchiba, N. Harada, K. Okajima, 2002, The Journal of laboratory and clinical medicine.

Role of neutrophil elastase in stress-induced gastric mucosal injury in rats.

T. Irie, Wenge Liu, H. Isobe, 1998, The Journal of laboratory and clinical medicine.

Adenosine and selective A(2A) receptor agonists reduce ischemia/reperfusion injury of rat liver mainly by inhibiting leukocyte activation.

N. Harada, K. Okajima, K. Ohshima, 2000, The Journal of pharmacology and experimental therapeutics.

Rebamipide prevents indomethacin-induced gastric mucosal lesion formation by inhibiting activation of neutrophils in rats.

H. Okabe, H. Isobe, N. Harada, 1998, Digestive diseases and sciences.

Inhibition of Neutrophil Activation by Lafutidine, an H2-receptor Antagonist, Through Enhancement of Sensory Neuron Activation Contributes to the Reduction of Stress-Induced Gastric Mucosal Injury in Rats

N. Harada, K. Okajima, 2007, Digestive Diseases and Sciences.

Ranitidine reduces ischemia/reperfusion-induced liver injury in rats by inhibiting neutrophil activation.

M. Uchiba, N. Harada, K. Okajima, 2002, The Journal of pharmacology and experimental therapeutics.

Role of granulocyte elastase in ischemia/reperfusion injury of rat liver.

S. Kushimoto, K. Takatsuki, H. Okabe, 1996, Critical care medicine.

Danaparoid sodium reduces ischemia/reperfusion-induced liver injury in rats by attenuating inflammatory responses

M. Uchiba, N. Harada, K. Okajima, 2006, Thrombosis and Haemostasis.

Antithrombin reduces reperfusion-induced liver injury in mice by enhancing sensory neuron activation

H. Kurihara, N. Nakagata, M. Uchiba, 2006, Thrombosis and Haemostasis.

Dalteparin, a Low-Molecular-Weight Heparin, Reduces Ischaemia/Reperfusion-Induced Liver Injury in Rats by Increasing the Hepatic Level of Prostacyclin

M. Uchiba, N. Harada, K. Okajima, 2000, Pathophysiology of Haemostasis and Thrombosis.

Resveratrol improves cognitive function in mice by increasing production of insulin-like growth factor-I in the hippocampus.

H. Kurihara, N. Nakagata, N. Harada, 2011, The Journal of nutritional biochemistry.

Rebamipide Decreases the Susceptibility of Gastric Mucosa to Acid-Induced Injury in Rats by Inhibiting Neutrophil Activation

Wenge Liu, N. Harada, K. Okajima, 2005, Digestive Diseases and Sciences.

Antithrombin reduces endotoxin-induced hypotension by enhancing pulmonary sensory neuron activation in rats

H. Isobe, M. Uchiba, N. Harada, 2006, Thrombosis and Haemostasis.

Rapid assay for plasma soluble E-selectin predicts the development of acute respiratory distress syndrome in patients with systemic inflammatory response syndrome.

N. Harada, K. Okajima, T. Nakagawa, 2006, Translational research : the journal of laboratory and clinical medicine.

Role of prostacyclin in the development of compression trauma-induced spinal cord injury in rats.

N. Harada, K. Okajima, Y. Taoka, 2006, Journal of neurotrauma.

Limaprost reduces motor disturbances by increasing the production of insulin-like growth factor I in rats subjected to spinal cord injury.

H. Ishikura, N. Harada, K. Okajima, 2010, Translational research : the journal of laboratory and clinical medicine.

AT(1) receptor blockers increase insulin-like growth factor-I production by stimulating sensory neurons in spontaneously hypertensive rats.

Kenji Okajima, Naoaki Harada, Nobuhiko Shimozawa, 2009, Translational research : the journal of laboratory and clinical medicine.

Donepezil Improves Cognitive Function in Mice by Increasing the Production of Insulin-Like Growth Factor-I in the Hippocampus

H. Kurihara, K. Sobue, N. Nakagata, 2009, Journal of Pharmacology and Experimental Therapeutics.

Desalted deep-sea water improves cognitive function in mice by increasing the production of insulin-like growth factor-I in the hippocampus.

H. Kurihara, N. Nakagata, N. Harada, 2011, Translational research : the journal of laboratory and clinical medicine.

Stimulation of sensory neurons improves cognitive function by promoting the hippocampal production of insulin-like growth factor-I in mice.

H. Kurihara, N. Nakagata, N. Harada, 2009, Translational research : the journal of laboratory and clinical medicine.

Antithrombin Reduces Ischemia/reperfusion-induced Renal Injury in Rats by Inhibiting Leukocyte Activation through Promotion of Prostacyclin Production

T. Noguchi, H. Isobe, M. Uchiba, 2022 .

Antithrombin reduces the ischemia/reperfusion-induced hepatic injury by increasing hepatic levels of prostacyclin through activation of capsaicin-sensitive sensory neurons in rats

M. Uchiba, N. Harada, K. Okajima, 2002, Critical Care.

Cilostazol improves cognitive function in mice by increasing the production of insulin-like growth factor-I in the hippocampus

H. Kurihara, N. Nakagata, N. Harada, 2010, Neuropharmacology.

Promotion of insulin-like growth factor-I production by sensory neuron stimulation; molecular mechanism(s) and therapeutic implications.

N. Harada, K. Okajima, 2008, Current medicinal chemistry.

ACTIVATED PROTEIN C PREVENTS ENDOTOXIN-INDUCED HYPOTENSION IN RATS BY INHIBITING INDUCTION OF NITRIC OXIDE SYNTHASE: 167

H. Isobe, N. Harada, K. Okajima, 1999 .

Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans.

H. Kurihara, N. Nakagata, N. Harada, 2008, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Activated Protein C Prevents Endotoxin-Induced Hypotension in Rats by Inhibiting Excessive Production of Nitric Oxide

H. Isobe, M. Uchiba, N. Harada, 2001, Circulation.

Regulation of inflammatory responses by sensory neurons: molecular mechanism(s) and possible therapeutic applications.

N. Harada, K. Okajima, 2006, Current medicinal chemistry.

A Novel Role of Gastric PGI2 in Gastric Cytoprotection

H. Okabe, H. Isobe, N. Harada, 1998 .

Desalted deep-sea water improves cognitive function in mice by increasing the production of insulin-like growth factor-I in the hippocampus.

H. Kurihara, N. Nakagata, N. Harada, 2011, Translational research : the journal of laboratory and clinical medicine.

[Acute lung injury/acute respiratory distress syndrome: progress in diagnosis and treatment. Topics: IV. Recent topics: 1. New therapeutic agents for ARDS].

N. Harada, K. Okajima, Chen Ren, 2011, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine.

ANTITHROMBIN PREVENTS ENDOTOXIN-INDUCED HYPOTENSION IN RATS BY INHIBITING INDUCTION OF NITRIC OXIDE SYNTHETHASE

H. Isobe, N. Harada, K. Okajima, 1999 .