Heesoon Lee

发表

Inhibitory effect of chroman carboxamide on interleukin-6 expression in response to lipopolysaccharide by preventing nuclear factor-kappaB activation in macrophages.

Byung Hak Kim, Youngsoo Kim, K. Min, 2006, European journal of pharmacology.

Inhibitory effect of 6-hydroxy-7-methoxychroman-2-carboxylic acid phenylamide on nitric oxide and interleukin-6 production in macrophages.

Youngsoo Kim, E. Chung, Heesoon Lee, 2005, Life sciences.

Inhibitory mechanism of chroman compound on LPS-induced nitric oxide production and nuclear factor-kappaB activation.

Byung Hak Kim, Youngsoo Kim, K. Min, 2004, Biochemical and biophysical research communications.

Inhibitory effect of 2'-hydroxycinnamaldehyde on nitric oxide production through inhibition of NF-kappa B activation in RAW 264.7 cells.

Sun Young Lee, J. Hong, H. Yoo, 2005, Biochemical pharmacology.

Induction of Paraptotic Cell Death in Breast Cancer Cells by a Novel Pyrazolo[3,4-h]quinoline Derivative through ROS Production and Endoplasmic Reticulum Stress

P. Nguyen, Chang Hoon Lee, Heesoon Lee, 2022, Antioxidants.

Inhibitory effects of OD 78 [3-(4-bromo-phenoxy)-4,5-dihydroxybenzoic acid-methyl ester] on the proliferation and migration of TNF-α-induced rat aortic smooth muscle cells

Y. Yun, J. Hong, Myung-Koo Lee, 2011, Archives of pharmacal research.

A new anti-inflammatory agent KL-1037 represses proinflammatory cytokine and inducible nitric oxide synthase (iNOS) gene expression in activated microglia

T. Joh, Hee-Sun Kim, M. Woo, 2004, Neuropharmacology.

Inhibition of inflammatory mediators and cell migration by 1,2,3,4-tetrahydroquinoline derivatives in LPS-stimulated BV2 microglial cells via suppression of NF-κB and JNK pathway.

Heesoon Lee, Jungsook Cho, Yeonsoo Oh, 2020, International immunopharmacology.

Synthesis and in Vitro cytotoxic activities of 2-alkyl-2,3-dihydro-1H-2,6-diazacyclopenta[b]anthracene-5,10-diones

S. Han, Kiho Lee, J. Kang, 2010, Archives of pharmacal research.

Synthesis and cytotoxic activities of 2-alkyl-2,3-dihydro-1H-2,6,9-triazacyclopenta[b]anthracene-5,10-diones

J. Kwon, Heesoon Lee, Jae-Hwan Kwak, 2008, Archives of pharmacal research.

Synthesis of chroman-2-carboxylic acid N-(substituted)phenylamides and their inhibitory effect on nuclear factor-κB (NF-κB) activation

B. Hwang, Youngsoo Kim, Han-young Kang, 2008 .

Structure-activity relationships of 6-hydroxy-7-methoxychroman-2-carboxylic acid N-(substituted)phenylamides as inhibitors of nuclear factor-kB activation

Byung Hak Kim, Youngsoo Kim, Heesoon Lee, 2007 .

Cytokine-induced killer cells hunt individual cancer cells in droves in a mouse model

J. Hong, S. Han, Youngsoo Kim, 2017, Cancer Immunology, Immunotherapy.

Development of Novel 1,2,3,4-Tetrahydroquinoline Scaffolds as Potent NF-κB Inhibitors and Cytotoxic Agents.

S. Han, Youngsoo Kim, Kiho Lee, 2016, ACS medicinal chemistry letters.

Design and synthesis of 3,4-dihydro-2H-benzo[h]chromene derivatives as potential NF-κB inhibitors.

S. Han, Youngsoo Kim, J. Yun, 2014, Bioorganic & medicinal chemistry letters.

Synthesis and NF-κB Inhibitory Activities of N-Substituted-aryl-3-phenylpropanamide Derivatives

Youngsoo Kim, Heesoon Lee, Jae-Kyung Jung, 2015 .

γ ‐Functionalization of α,β ‐Unsaturated Nitriles under Mild Conditions: Versatile Synthesis of 4‐Aryl‐2‐Bromopyridines

Seung‐Yong Seo, K. Jung, Heesoon Lee, 2019, Advanced Synthesis & Catalysis.

Neuroprotective and Antioxidant Effects of Novel Benzofuran-2-Carboxamide Derivatives

S. Bose, Heesoon Lee, Jungsook Cho, 2015, Biomolecules & therapeutics.

Synthesis, biological evaluation, and metabolic stability of chlorogenic acid derivatives possessing thiazole as potent inhibitors of α-MSH-stimulated melanogenesis.

J. Hong, Youngsoo Kim, Seung‐Yong Seo, 2017, Bioorganic & medicinal chemistry letters.

Synthesis and characterization of Rosuvastatin calcium impurity A; a HMG-CoA reductase inhibitor

Eunhwa Lee, Kiho Lee, Young Hee Lee, 2017 .

Antioxidant and Anti-inflammatory Activities of N-((3,4-Dihydro-2H-benzo[h]chromene-2-yl)methyl)-4-methoxyaniline in LPS-Induced BV2 Microglial Cells.

M. Moniruzzaman, S. Bose, Heesoon Lee, 2015, Biological & pharmaceutical bulletin.

A novel synthetic compound MCAP suppresses LPS-induced murine microglial activation in vitro via inhibiting NF-kB and p38 MAPK pathways

K. Suk, D. Choi, In-Su Kim, 2016, Acta Pharmacologica Sinica.

Design and synthesis of 4-O-methylhonokiol analogs as inhibitors of cyclooxygenase-2 (COX-2) and PGF₁ production.

J. Hong, Sukgil Song, S. Han, 2012, Bioorganic & medicinal chemistry.

Rapid, Operationally Simple, and Metal‐free NBS Mediated One‐pot Synthesis of 1,2‐Naphthoquinone from 2‐Naphthol

Heesoon Lee, Jae-Kyung Jung, M. Viji, 2018 .

A new furofuran lignan from Isodon japonicus

S. Hong, Mi Kyeong Lee, B. Hwang, 2009, Archives of pharmacal research.

Synthesis of 7-hydroxy-4-oxo-4H-chromene-and 7-hydroxychroman-2-carboxylic acidN-alkyl amides and their antioxidant activities

Heesoon Lee, Jae-Hwan Kwak, Jungsook Cho, 2006, Archives of pharmacal research.

Synthesis of 6-hydroxy-7-methoxy-4-oxo-4H-chromene-2-carboxylic acidN-alkyl amides and their antioxidant activity

Heesoon Lee, Jungsook Cho, Jae-Kyung Jung, 2006, Archives of pharmacal research.

Melampolides from the leaves of Smallanthus sonchifolius and their inhibitory activity of lps-induced nitric oxide production.

Dongho Lee, Myung-Koo Lee, S. Hong, 2008, Chemical & pharmaceutical bulletin.

Synthesis and evaluation of 6-hydroxy-7-methoxy-4-chromanone- and chroman-2-carboxamides as antioxidants.

E. Theodorakis, Heesoon Lee, Jungsook Cho, 2005, Bioorganic & medicinal chemistry letters.

Nuclear Entry of CRTC1 as Druggable Target of Acquired Pigmentary Disorder

Song-Hee Kim, J. Hong, Jiyeon Lee, 2019, Theranostics.

α-Hydroxy acid as an aldehyde surrogate: metal-free synthesis of pyrrolo[1,2-a]quinoxalines, quinazolinones, and other N-heterocycles via decarboxylative oxidative annulation reaction

Kiho Lee, Heesoon Lee, Jae-Kyung Jung, 2020, RSC advances.

Concise Synthesis of Broussonone A

J. Hong, Mi Kyeong Lee, Yeon-Ju Lee, 2015, Molecules.

Fermi-edge singularity of two dimensional electrons in asymmetric coupled double quantum wells

Eun-Gu Lee, Joo In Lee, H. Na, 1995 .

Design, synthesis and biological evaluation of 1,3-diphenylbenzo[f][1,7]naphthyrdines.

Kiho Lee, Youngjoo Kwon, Kyu-Yeon Jun, 2017, Bioorganic & medicinal chemistry.

A facile one-pot regioselective synthesis of functionalized novel benzo[f]chromeno[4,3-b][1,7]naphthyridines and benzo[f][1,7]naphthyridines via an imino Diels-Alder reaction

Kiho Lee, Heesoon Lee, Jae-Kyung Jung, 2017 .

Synthesis and in vitro cytotoxicity of (RS)-20-desethyl-20-substituted camptothecin analogues

Jaeyun Kim, Heesoon Lee, Hogyu Han, 1996 .

ent-Kaurane diterpenoids from Isodon japonicus.

J. Hong, Dongho Lee, S. Hong, 2007, Journal of natural products.

A novel and efficient amidation of 2-aminothiazole

J. Hong, Hyi-Seung Lee, Yeon-Ju Lee, 2014 .

Regiodivergent Organocatalytic Reactions

Heesoon Lee, Jae-Kyung Jung, S. Lanka, 2021, Catalysts.

Transition metal-free synthesis of quinazolinones using dimethyl sulfoxide as a synthon.

Kiho Lee, Heesoon Lee, Jae-Kyung Jung, 2019, Organic & biomolecular chemistry.

Metal-free approach for the ʟ-proline mediated synthesis of nitrones from nitrosobenzene

Kiho Lee, Young Hee Lee, Heesoon Lee, 2018, Tetrahedron.

Organocatalytic and Regiodivergent Mannich Reaction of Ketones with Benzoxazinones

K. Oh, Heesoon Lee, Jae-Kyung Jung, 2018, Advanced Synthesis & Catalysis.

Expedient synthesis of 4-O-methylhonokiol via Suzuki–Miyaura cross-coupling

J. Hong, S. Han, Seung‐Yong Seo, 2011 .

Transition-metal-free, atom-economical cascade synthesis of novel 2-sulfonated-benzo[f][1,7]naphthyridines and their cytotoxic activities

Kiho Lee, J. Kang, Heesoon Lee, 2018 .

Synthesis of novel diaryl ethers and their evaluation as antimitotic agents.

S. Ahn, J. Yang, N. Choi, 2007, Bioorganic & medicinal chemistry letters.

Design, Synthesis, and Cytotoxicity and Topoisomerase I/IIα Inhibition Activity of Pyrazolo[4,3-f]quinoline Derivatives

Youngjoo Kwon, J. Kang, Heesoon Lee, 2022, Pharmaceuticals.

Synthesis of N-arylindazole-3-carboxamide and N-benzoylindazole derivatives and their evaluation against α-MSH-stimulated melanogenesis.

Youngsoo Kim, Kiho Lee, Heesoon Lee, 2019, Bioorganic & medicinal chemistry letters.

Synthesis and nuclear factor-κB inhibitory activities of 6- or 7-methylchroman-2-carboxylic acid N-(substituted) phenylamides

J. Hong, B. Hwang, Youngsoo Kim, 2009, Archives of pharmacal research.

Stereoselective synthesis of (E)- and (Z)-enol ethers from β-amino aldehydes

J. Hong, Yongseok Choi, Heesoon Lee, 2007 .

Synthesis and antitumor activity of 7-substituted 20(RS)-camptothecin analogues

Kiho Lee, Heesoon Lee, H. Kim, 1996 .

Synthesis and antifungal activity of 6,7-bis-[s-(aryl)thio]-5,8-quinolinediones

C. Ryu, Heesoon Lee, Yangyang Sun, 2002, Archives of pharmacal research.

A regioselective synthesis of β-lactones; Bromolactonization of 2-substituted-1-cyclohexenyl-1-acetic acid

Heesoon Lee, S. Jew, Bon-Am Koo, 1994 .

Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors.

Kiho Lee, Youngjoo Kwon, Kyu-Yeon Jun, 2018, Bioorganic & medicinal chemistry.

Arteminolides B, C, and D, new inhibitors of farnesyl protein transferase from Artemisia argyi.

K. Son, B. Kwon, Jongheon Shin, 2002, The Journal of organic chemistry.

Arteminolide, an Inhibitor of Farnesyl Transferase from Artemisia sylvatica.

B. Kwon, Mi‐jeong Kim, S. Bok, 1998, The Journal of organic chemistry.

Suppression of Pax3–MITF-M Axis Protects from UVB-Induced Skin Pigmentation by Tetrahydroquinoline Carboxamide

Song-Hee Kim, S. Han, Youngsoo Kim, 2020, International journal of molecular sciences.

Synthesis of Obovatol Derivatives and Their Preliminary Evaluation as Antitumor Agents

J. Hong, J. Yang, Y. Suh, 2007 .

A novel cyclization/oxidation strategy for a two-step synthesis of (Z)-aurone

H. Kim, Heesoon Lee, Jae-Kyung Jung, 2017 .

Inhibitory Effect of Chlorogenic Acid Analogues Comprising Pyridine and Pyrimidine on α-MSH-Stimulated Melanogenesis and Stability of Acyl Analogues in Methanol

Seung‐Yong Seo, Kiho Lee, Heesoon Lee, 2021, Pharmaceuticals.

Synthesis andin vitro evaluation of 4-substituted-1-azaanthraquinones

Young-ho Kim, Heesoon Lee, Jungsook Cho, 1998 .

Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of α-MSH-stimulated melanogenesis.

J. Hong, Youngsoo Kim, Seung‐Yong Seo, 2017, Bioorganic & medicinal chemistry letters.

Prenylated xanthones from the root bark of Cudrania tricuspidata.

Ji Hye Hwang, Y. Yun, Dongho Lee, 2007, Journal of natural products.

Stereoselective conjugate additions of allyl silanes and enol silyl ethers to a chiral 2-substituted-2-cyclohexen-1-one

Heesoon Lee, A. Schultz, 1992 .

Stereoselective Conjugate Additions of Allyl Silanes and Enol Silyl Ethers to a Chiral 2-Substituted 2-Cyclohexen-1-one.

Heesoon Lee, A. Schultz, 1992 .

Design, synthesis, and biological evaluation of benzofuran- and 2,3-dihydrobenzofuran-2-carboxylic acid N-(substituted)phenylamide derivatives as anticancer agents and inhibitors of NF-κB.

S. Han, Youngsoo Kim, Kiho Lee, 2015, Bioorganic & medicinal chemistry letters.

Novel NF-κB inhibitors: a patent review (2011 – 2014)

Heesoon Lee, Jae-Kyung Jung, Sateesh Kumar Arepalli, 2015, Expert opinion on therapeutic patents.

Structure-activity relationship of indoline-2-carboxylic acid N-(substituted)phenylamide derivatives.

J. Hong, B. Hwang, S. Han, 2010, Bioorganic & medicinal chemistry letters.

Nuclear factor-kappa B inhibitors; a patent review (2006 – 2010)

Heesoon Lee, Jae-Hwan Kwak, Jae-Kyung Jung, 2011, Expert opinion on therapeutic patents.

Total Synthesis of Isohericerinol A and Its Analogues to Access Their Potential Neurotrophic Effects.

S. Kim, Heesoon Lee, S. Hong, 2022, The Journal of organic chemistry.

Design and synthesis of 2,3-dihydro- and 5-chloro-2,3-dihydro-naphtho-[1,2-b]furan-2-carboxylic acid N-(substitutedphenyl)amide analogs and their biological activities as inhibitors of NF-κB activity and anticancer agents

J. Yun, J. Kang, Heesoon Lee, 2016, Archives of Pharmacal Research.

J. Hong, Youngsoo Kim, J. Yun, 2016, Archives of pharmacal research.

Caffeic Acid Cyclohexylamide Rescues Lethal Inflammation in Septic Mice through Inhibition of IκB Kinase in Innate Immune Process

J. Hong, S. Han, Youngsoo Kim, 2017, Scientific Reports.

Benzoxathiole Derivative Blocks Lipopolysaccharide-Induced Nuclear Factor-κB Activation and Nuclear Factor-κB-Regulated Gene Transcription through Inactivating Inhibitory κB Kinase β

Byung Hak Kim, S. Han, Youngsoo Kim, 2008, Molecular Pharmacology.

Anti‐cancer effect of N‐(3,5‐bis(trifluoromethyl)phenyl)‐5‐chloro‐2,3‐dihydronaphtho[1,2‐b]furan‐2‐carboxamide, a novel synthetic compound

H. Yoo, B. Hwang, M. Park, 2016, Molecular carcinogenesis.

Synthesis of chroman-2-carboxylic acid N-(substituted)phenylamides and their inhibitory effect on nuclear factor-kappaB (NF-kappaB) activation.

B. Hwang, Youngsoo Kim, Han-young Kang, 2008, Archives of pharmacal research.

Anti-Inflammatory and Anti-Migratory Activities of Isoquinoline-1-Carboxamide Derivatives in LPS-Treated BV2 Microglial Cells via Inhibition of MAPKs/NF-κB Pathway

Heesoon Lee, Jungsook Cho, Jae-Kyung Jung, 2020, International journal of molecular sciences.

Inhibitory effect of green tea extract on beta-amyloid-induced PC12 cell death by inhibition of the activation of NF-kappaB and ERK/p38 MAP kinase pathway through antioxidant mechanisms.

Jin Tae Hong, Tae Youl Ha, Jae Woong Lee, 2005, Brain research. Molecular brain research.

Design, synthesis, and biological evaluation of potent 1,2,3,4-tetrahydroisoquinoline derivatives as anticancer agents targeting NF-κB signaling pathway.

Kiho Lee, J. Kang, S. Lee, 2021, Bioorganic & Medicinal Chemistry.

Synthesis and anti-platelet activity of obovatol derivatives

Y. Yun, J. Hong, N. Choi, 2011, Archives of pharmacal research.

Methyl Aryloxy Gallates as Regulators of Vascular Smooth Muscle Cell Proliferation

S. Ahn, Y. Yun, J. Hong, 2009 .

Antioxidant and Neuroprotective Effects of N-((3,4-Dihydro-2H-benzo[h]chromen-2-yl)methyl)-4-methoxyaniline in Primary Cultured Rat Cortical Cells: Involvement of ERK-CREB Signaling

Heesoon Lee, Kyeongjun Lee, Jungsook Cho, 2018, Molecules.

Targeting IKKβ Activity to Limit Sterile Inflammation in Acetaminophen-Induced Hepatotoxicity in Mice

Song-Hee Kim, Jin Yong Song, Heesoon Lee, 2023, Pharmaceutics.

9‐Borabicyclononyl Trifluoromethanesulfonate

D. Garvey, E. Theodorakis, Heesoon Lee, 2006 .

Synthesis and Spectral Characterization of Impurities of a COX‐2 Selective Drug, Celecoxib

Eunhwa Lee, Kiho Lee, Young Hee Lee, 2019, Bulletin of the Korean Chemical Society.

Synthesis and in vitro evaluation of 7-dialkylaminomethylbenzo[g]quinoxaline-5,10-diones.

Heesoon Lee, Jungsook Cho, Jae-Kyung Jung, 2004, Bioorganic & medicinal chemistry letters.

Concise synthesis of Obovatol: Chemoselective ortho-bromination of phenol and survey of Cu-catalyzed diaryl ether couplings

Y. Yun, J. Hong, Soo Jae Lee, 2008, Archives of pharmacal research.

Reagent-Free Intramolecular Hydrofunctionalization: A Regioselective 6-endo-dig Cyclization of o-Alkynoylphenols

Y. Kang, Heesoon Lee, Jae-Kyung Jung, 2022, Green Chemistry.