Ahmed H. E. Hassan

发表

Repurposing mosloflavone/5,6,7-trimethoxyflavone-resveratrol hybrids: Discovery of novel p38-α MAPK inhibitors as potent interceptors of macrophage-dependent production of proinflammatory mediators.

Kyung-Tae Lee, Hwi-ho Lee, Ji-Sun Shin, 2019, European journal of medicinal chemistry.

Mosloflavone-Resveratrol Hybrid TMS-HDMF-5z Exhibits Potent In Vitro and In Vivo Anti-Inflammatory Effects Through NF-κB, AP-1, and JAK/STAT Inactivation

Kyung-Sook Chung, Hwi-ho Lee, Ji-Sun Shin, 2022, Frontiers in Pharmacology.

Enantiopure methoxetamine stereoisomers: chiral resolution, conformational analysis, UV-circular dichroism spectroscopy and electronic circular dichroism

Ji-Young Kim, Yong Sup Lee, J. Cheong, 2021 .

Heterocyclic Synthesis via Enaminones: Synthesis and Molecular Docking Studies of Some Novel Heterocyclic Compounds Containing Sulfonamide Moiety

Ahmed H. E. Hassan, 2014 .

Design, synthesis, biological evaluation and molecular modelling of 2‐(2‐aryloxyphenyl)‐1,4‐dihydroisoquinolin‐3(2H)‐ones: A novel class of TSPO ligands modulating amyloid‐&bgr;‐induced mPTP opening

Ki Duk Park, Jiyoun Lee, Bongjin Moon, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Investigating the structure–activity relationship of marine natural polyketides as promising SARS-CoV-2 main protease inhibitors

Khaled M. Darwish, Sameh S. Elhady, A. A. Al-karmalawy, 2021, RSC advances.

Synthesis of the Tricyclic Ring Structure of Daphnanes via Intramolecular [4 + 3] Cycloaddition/SmI2-Pinacol Coupling.

Jae Kyun Lee, Y. Cho, A. Pae, 2015, Organic letters.

3',4'-Dihydroxyflavone mitigates inflammatory responses by inhibiting LPS and TLR4/MD2 interaction.

Kyung-Sook Chung, Hwi-ho Lee, Ji-Sun Shin, 2022, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Natural products hybrids: 3,5,4'-Trimethoxystilbene-5,6,7-trimethoxyflavone chimeric analogs as potential cytotoxic agents against diverse human cancer cells.

Ji-Sun Shin, Yong Sup Lee, Kyung-Tae Lee, 2019, European journal of medicinal chemistry.

Identification of Novel Aryl Carboxamide Derivatives as Death-Associated Protein Kinase 1 (DAPK1) Inhibitors with Anti-Proliferative Activities: Design, Synthesis, In Vitro, and In Silico Biological Studies

E. Roh, Ahmed H. E. Hassan, E. M. Ali, 2022, Pharmaceuticals.

Bestatin analogs-4-quinolinone hybrids as antileishmanial hits: Design, repurposing rational, synthesis, in vitro and in silico studies.

T. Phan, J. No, Yeon Ju Kim, 2023, European journal of medicinal chemistry.

Design, synthesis, and repurposing of O6-aminoalkyl-sulfuretin analogs towards discovery of potential lead compounds as antileishmanial agents.

T. Phan, J. No, Yeon Ju Kim, 2023, European journal of medicinal chemistry.

Synthesis and Biological Evaluation of O6-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative Diseases

Jong-Hyun Park, J. Ryu, Yeon Ju Kim, 2023, Antioxidants.

A Novel Hydroxyapatite/Vitamin B12 Nanoformula for Treatment of Bone Damage: Preparation, Characterization, and Anti-Arthritic, Anti-Inflammatory, and Antioxidant Activities in Chemically Induced Arthritic Rats

A. Farghali, M. Ghoneim, A. Gamal, 2023, Pharmaceuticals.

Pyrrolidine-based 3-deoxysphingosylphosphorylcholine analogs as possible candidates against neglected tropical diseases (NTDs): identification of hit compounds towards development of potential treatment of Leishmania donovani

Yong Sup Lee, Seo-Young Yoon, H. Jeon, 2021, Journal of enzyme inhibition and medicinal chemistry.

Exploring the Antimicrobial Activity of Sodium Titanate Nanotube Biomaterials in Combating Bone Infections: An In Vitro and In Vivo Study

Atiah H. Almalki, A. Farghali, M. Ghoneim, 2023, Antibiotics.

Design, synthesis, and evaluation of new anti-inflammatory natural products amide derivatives endowed with anti-blood cancer activity towards development of potential multifunctional agents against hematological cancers.

K. Lee, S. Jung, Ahmed H. E. Hassan, 2023, European journal of medicinal chemistry.

Positional scanning of natural product hispidol’s ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases

Ki Duk Park, Jong-Hyun Park, H. Jeon, 2022, Journal of enzyme inhibition and medicinal chemistry.

Scaffold hopping of N-benzyl-3,4,5-trimethoxyaniline: 5,6,7-Trimethoxyflavan derivatives as novel potential anticancer agents modulating hippo signaling pathway.

Yeon Ju Kim, S. Jung, Ahmed H. E. Hassan, 2023, European journal of medicinal chemistry.

Small Molecules Incorporating Privileged Amidine Moiety as Potential Hits Combating Antibiotic-Resistant Bacteria

A. Farahat, Ahmed H. E. Hassan, Justin R. Lenhard, 2023, Pharmaceuticals.

Escaping ESKAPE resistance: in vitro and in silico studies of multifunctional carbamimidoyl-tethered indoles against antibiotic-resistant bacteria

A. Farahat, Ahmed H. E. Hassan, Justin R. Lenhard, 2023, Royal Society Open Science.

In Silico and In Vitro Evaluation of Some Amidine Derivatives as Hit Compounds towards Development of Inhibitors against Coronavirus Diseases

J. Gohda, M. Shirouzu, Takehisa Matsumoto, 2023, Viruses.

Design, Rational Repurposing, Synthesis, In Vitro Evaluation, Homology Modeling and In Silico Study of Sulfuretin Analogs as Potential Antileishmanial Hit Compounds

T. Phan, J. No, Ahmed H. E. Hassan, 2022, Pharmaceuticals.

Rational repurposing, synthesis, in vitro and in silico studies of chromone-peptidyl hybrids as potential agents against Leishmania donovani

T. Phan, J. No, Yeon Ju Kim, 2023, Journal of Enzyme Inhibition and Medicinal Chemistry.

Design, synthesis, and study of novel phenethyl-based antitumor phospholipids downregulating p38 mitogen-activated protein kinase

K. Lee, Yeon Ju Kim, Ahmed H. E. Hassan, 2023, Journal of Enzyme Inhibition and Medicinal Chemistry.

2-((5-(5-Methyl-2-phenyl-1H-imidazol-4-yl)-1,3,4-oxadiazol-2-yl)thio)-1-phenylethan-1-one

J. Fettinger, A. Farahat, A. Mabied, 2023, Molbank.

Repurposing of conformationally-restricted cyclopentane-based AKT-inhibitors leads to discovery of potential and more selective antileishmanial agents than miltefosine.

T. Phan, J. No, Yeon Ju Kim, 2023, Bioorganic chemistry.

Design, synthesis and evaluation of alkylphosphocholine-gefitinib conjugates as multitarget anticancer agents

N. Kim, Ahmed H. E. Hassan, Dong-Hyun Kim, 2017, Archives of Pharmacal Research.

Integrating computational methods guided the discovery of phytochemicals as potential Pin1 inhibitors for cancer: pharmacophore modeling, molecular docking, MM-GBSA calculations and molecular dynamics studies

Ahmed H. E. Hassan, A. A. Alzain, Sabrin R. M. Ibrahim, 2024, Frontiers in chemistry.

Characterization and Bio-Evaluation of the Synergistic Effect of Simvastatin and Folic Acid as Wound Dressings on the Healing Process

K. Lee, M. Saddik, M. El-Mokhtar, 2023, Pharmaceutics.

Concise Synthesis of Aloesone and Aloesol Natural Products

Yong Sup Lee, Jiyong Lee, M. Saleem, 2017 .

Inherent photocatalytic activity of luminescent multi-doped carbon dots manufactured from expired medicine and its application for efficient water remediation and nanosensing

R. El-Shaheny, Ahmed H. E. Hassan, R. Abo Shabana, 2024, Microchemical Journal.

Therapeutic role of 2-stearoxyphenethyl phosphocholine targeting microtubule dynamics and Wnt/β-catenin/EMT signaling in human colorectal cancer cells.

Ahmed H. E. Hassan, Jeong-Hun Lee, Sang-Eun Park, 2023, Life sciences.

Repurposing Synthetic Congeners of a Natural Product Aurone Unveils a Lead Antitumor Agent Inhibiting Folded P-Loop Conformation of MET Receptor Tyrosine Kinase

Yeon Ju Kim, Ahmed H. E. Hassan, S. M. El-Sayed, 2023, Pharmaceuticals.

Fabrication of an In Situ pH-Responsive Raloxifene-Loaded Invasome Hydrogel for Breast Cancer Management: In Vitro and In Vivo Evaluation

K. Lee, A. Belal, H. Farouk, 2024, Pharmaceuticals.

Tetraenone A: A New β-Ionone Derivative from Tetraena aegyptia

G. Mohamed, A. Zaki, Bayan E Ainousah, 2023, Metabolites.