T. Takai

发表

Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors.

Toshimasa Tanaka, Biching Sang, T. Kawamoto, 2018, Bioorganic & medicinal chemistry.

Discovery of novel 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine derivatives as γ-secretase modulators (Part 2).

T. Tsukamoto, Naohiro Taya, Tomoko Igari, 2016, Bioorganic & medicinal chemistry.

Discovery of novel 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine derivatives as γ-secretase modulators.

Yasutaka Hoashi, Tomoko Igari, T. Takai, 2015, Bioorganic & medicinal chemistry letters.

Discovery of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazoles as novel class of corticotropin releasing factor 1 receptor antagonists.

Takahiko Yano, Yasutaka Hoashi, Y. Kosugi, 2018, Bioorganic & medicinal chemistry.

Facile synthesis of (-)-tabtoxinine-β-lactam and its (3′R)-isomer

T. Oritani, H. Kiyota, S. Kuwahara, 2004 .

1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT₂-selective agonists.

Masaharu Nakayama, K. Hirai, Yasutaka Hoashi, 2011, Journal of medicinal chemistry.

Practical application of 3-substituted-2,6-difluoropyridines in drug discovery: Facile synthesis of novel protein kinase C theta inhibitors.

S. Sasaki, T. Tsukamoto, Tomoya Yukawa, 2017, Bioorganic & medicinal chemistry letters.

Synthesis of 4-aza analog of ramelteon: a novel tricyclic 1,6,7,8-tetrahydro-2H-cyclopenta[d]furo[2,3-b]pyridine derivative as melatonin receptor ligand

Yasutaka Hoashi, O. Uchikawa, T. Takai, 2011 .

Synthesis of a novel series of tricyclic dihydrofuran derivatives: discovery of 8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridines as melatonin receptor (MT1/MT2) ligands.

Masaharu Nakayama, K. Hirai, Yasutaka Hoashi, 2011, Journal of medicinal chemistry.

Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKCθ inhibitors.

M. Klein, Biching Sang, T. Arita, 2016, Bioorganic & medicinal chemistry.

Syntheses and odour descriptions of cyclopropanated compounds: 4.1 modiﬁcation of aliphatic dienols

H. Kiyota, S. Kuwahara, T. Takai, 2003 .

Syntheses and odour descriptions of cyclopropanated compounds 3.1 Analogues of leaf alcohol, its esters and leaf acetal

T. Oritani, H. Kiyota, S. Kuwahara, 2002 .

Discovery of a novel B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor by utilizing structure-based drug design.

Terufumi Takagi, Kotaro Sakamoto, G. Snell, 2017, Bioorganic & medicinal chemistry.

Synthesis of pyrazolo[1,5-a]pyridines by thermal intramolecular cyclization

Yasutaka Hoashi, T. Takai, T. Koike, 2013 .