Tilak Khanal

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Endosulfan induces COX-2 expression via NADPH oxidase and the ROS, MAPK, and Akt pathways

Hyung Gyun Kim, E. Han, J. Choi, 2015, Archives of Toxicology.

Biotransformation of geniposide by human intestinal microflora on cytotoxicity against HepG2 cells.

Hyung Gyun Kim, J. Choi, H. Jeong, 2012, Toxicology letters.

Upregulation of CYP1B1 by hypoxia is mediated by ERα activation in breast cancer cells.

Hyung Gyun Kim, E. Han, H. Jeong, 2022, American journal of cancer research.

Protective role of metabolism by intestinal microflora in butyl paraben-induced toxicity in HepG2 cell cultures.

Hyung Gyun Kim, H. Jeong, T. Jeong, 2012, Toxicology letters.

Developing a panel of biomarkers and miRNA in patients with myocardial infarction for early intervention strategies of heart failure in West Virginian population

J. Shapiro, N. Puri, K. Sodhi, 2018, PloS one.

Inhibitory effect of dihydroartemisinin against phorbol ester-induced cyclooxygenase-2 expression in macrophages.

M. Jeong, Hyung Gyun Kim, E. Han, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Protective effects of saponins from the root of Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the activation of AMP-dependent protein kinase.

Y. Hwang, J. Choi, H. Jeong, 2009, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Saponins isolated from the root of Platycodon grandiflorum protect against acute ethanol-induced hepatotoxicity in mice.

Y. Hwang, J. Choi, H. Jeong, 2009, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Saponins, especially platycodin D, from Platycodon grandiflorum modulate hepatic lipogenesis in high-fat diet-fed rats and high glucose-exposed HepG2 cells.

Hyung Gyun Kim, Y. Hwang, J. Choi, 2013, Toxicology and applied pharmacology.

Phillyrin attenuates high glucose-induced lipid accumulation in human HepG2 hepatocytes through the activation of LKB1/AMP-activated protein kinase-dependent signalling.

Hyung Gyun Kim, Y. Hwang, J. Choi, 2013, Food chemistry.

Ethyl acetate extract of Psidium guajava inhibits IgE-mediated allergic responses by blocking FcεRI signaling.

Hyung Gyun Kim, E. Han, Y. Hwang, 2011, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways.

Hyung Gyun Kim, J. Choi, H. Jeong, 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Uremic Toxins Activates Na/K-ATPase Oxidant Amplification Loop Causing Phenotypic Changes in Adipocytes in In Vitro Models

D. E. Bartlett, J. Shapiro, K. Sodhi, 2018, International journal of molecular sciences.

Protective effect of caffeic acid phenethyl ester against carbon tetrachloride-induced hepatotoxicity in mice.

Y. Hwang, J. Choi, H. Jeong, 2008, Toxicology.

Cultivated ginseng inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in NC/Nga mice and TNF-α/IFN-γ-induced TARC activation in HaCaT cells.

Hyung Gyun Kim, Y. Hwang, J. Choi, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Topical application of Pleurotus eryngii extracts inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice by the regulation of Th1/Th2 balance.

Hyung Gyun Kim, E. Han, Y. Hwang, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Protective role of intestinal bacterial metabolism against baicalin-induced toxicity in HepG2 cell cultures.

Hyung Gyun Kim, J. Choi, B. Park, 2012, The Journal of toxicological sciences.

Role of metabolism by the human intestinal microflora in arbutin-induced cytotoxicity in HepG2 cell cultures.

Hyung Gyun Kim, Y. Hwang, H. Jeong, 2011, Biochemical and biophysical research communications.

1-Bromopropane up-regulates cyclooxygenase-2 expression via NF-κB and C/EBP activation in murine macrophages.

E. Han, J. Choi, H. Jeong, 2012, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-κB, C/EBP and AP-1 signaling pathways in murine macrophages.

Hyung Gyun Kim, E. Han, J. Choi, 2012, Food and Chemical Toxicology.

Anthocyanins from purple sweet potato attenuate dimethylnitrosamine-induced liver injury in rats by inducing Nrf2-mediated antioxidant enzymes and reducing COX-2 and iNOS expression.

Hyung Gyun Kim, Jin Young Kim, E. Han, 2011, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Platycodon grandiflorum root-derived saponins attenuate atopic dermatitis-like skin lesions via suppression of NF-κB and STAT1 and activation of Nrf2/ARE-mediated heme oxygenase-1.

Hyung Gyun Kim, E. Han, Y. Hwang, 2014, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Progression and dormancy in metastatic thyroid cancer: concepts and clinical implications

M. Ringel, Tilak Khanal, Neel Rajan, 2020, Endocrine.

Saponins from the Roots of Platycodon grandiflorum Suppresses TGFβ1-Induced Epithelial-Mesenchymal Transition Via Repression of PI3K/Akt, ERK1/2 and Smad2/3 Pathway in Human Lung Carcinoma A549 Cells

Hyung Gyun Kim, Y. Hwang, J. Choi, 2014, Nutrition and cancer.

Leptin induces CYP1B1 expression in MCF-7 cells through ligand-independent activation of the ERα pathway.

Hyung Gyun Kim, J. Choi, H. Jeong, 2014, Toxicology and applied pharmacology.

Akt isoform-specific effects on thyroid cancer development and progression in a murine thyroid cancer model

K. Coombes, K. L. La Perle, P. Tsichlis, 2020, Scientific Reports.

Antitumor efficacy of piperine in the treatment of human HER2-overexpressing breast cancer cells.

Hyung Gyun Kim, J. Choi, B. Park, 2013, Food chemistry.

Role of metabolism by human intestinal microflora in geniposide-induced toxicity in HepG2 cells

Hyung Gyun Kim, H. Jeong, Yong Sup Lee, 2012, Archives of pharmacal research.

Role of metabolism by human intestinal microflora in geniposide-induced toxicity in HepG2 cells

Hyung Gyun Kim, H. Jeong, T. Jeong, 2012, Archives of Pharmacal Research.

Metformin suppresses CYP1A1 and CYP1B1 expression in breast cancer cells by down-regulating aryl hydrocarbon receptor expression.

Hyung Gyun Kim, J. Choi, H. Jeong, 2014, Toxicology and applied pharmacology.

Deregulation of NR2E3, an orphan nuclear receptor, by benzo(a)pyrene-induced oxidative stress is associated with histone modification status change of the estrogen receptor gene promoter.

D. Choubey, Kyounghyun Kim, Abby L. Johnson, 2015, Toxicology letters.

Genipin induces cyclooxygenase-2 expression via NADPH oxidase, MAPKs, AP-1, and NF-κB in RAW 264.7 cells.

Hyung Gyun Kim, J. Choi, H. Jeong, 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Platycodi Radix attenuates dimethylnitrosamine-induced liver fibrosis in rats by inducing Nrf2-mediated antioxidant enzymes.

Hyung Gyun Kim, Y. Hwang, J. Choi, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer

A. Puga, S. Ho, Y. Leung, 2017, Scientific Reports.

Metformin inhibits heme oxygenase-1 expression in cancer cells through inactivation of Raf-ERK-Nrf2 signaling and AMPK-independent pathways.

Hyung Gyun Kim, J. Choi, H. Jeong, 2013, Toxicology and applied pharmacology.

Leptin induces CREB-dependent aromatase activation through COX-2 expression in breast cancer cells.

Hyung Gyun Kim, H. Jeong, T. Jeong, 2017, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

NR2E3 is a key component in p53 activation by regulating a long noncoding RNA DINO in acute liver injuries

S. Ho, Y. Leung, Kyounghyun Kim, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.