H. Jahns

发表

Pyridinylquinoxalines and pyridinylpyridopyrazines as lead compounds for novel p38 alpha mitogen-activated protein kinase inhibitors.

S. Laufer, P. Koch, H. Jahns, 2010, Journal of medicinal chemistry.

Site-specific conjugation of drug-like fragments to an antimiR scaffold as a strategy to target miRNAs inside RISC.

Jonathan Hall, J. Hall, J. Hunziker, 2016, Chemical communications.

Stereochemical and pharmacological properties of phosphorothioate siRNAs

H. Jahns, Hartmut Jahns, 2014 .

Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing

M. Manoharan, M. Egli, J. Plavec, 2021, Nucleic acids research.

Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivo

K. G. Rajeev, M. Manoharan, M. Egli, 2021, Nucleic acids research.

Incorporating a Thiophosphate Modification into a Common RNA Tetraloop Motif Causes an Unanticipated Stability Boost.

T. Lybrand, M. Manoharan, M. Egli, 2020, Biochemistry.

Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.

S. Rossi, Jonathan Hall, Martina Roos, 2016, Cancer research.

Stereochemical bias introduced during RNA synthesis modulates the activity of phosphorothioate siRNAs

Jonathan Hall, Martina Roos, Jochen Imig, 2015, Nature Communications.

Properties of short double-stranded RNAs carrying randomized base pairs: toward better controls for RNAi experiments

Jonathan Hall, H. Towbin, M. Menzi, 2015, RNA.

3-(4-Fluorophenyl)-6-methoxy-2-(4-pyridyl)quinoxaline

Dieter Schollmeyer, Stefan Laufer, Hartmut Jahns, 2009, Acta crystallographica. Section E, Structure reports online.

Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells

Jonathan Hall, J. Leroux, Soo Hyeon Lee, 2016, Molecular therapy. Nucleic acids.