T. Kirrane

发表

Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors.

K. Qian, J. Madwed, C. Pargellis, 2009, Bioorganic & medicinal chemistry letters.

The Wavelength of Maximum Polarization in the Chamaeleon Dark Cloud

J. Hough, J. Bailey, D. Whittet, 1986 .

Mitigation of Off-Target Adrenergic Binding and Effects on Cardiovascular Function in the Discovery of Novel Ribosomal S6 Kinase 2 Inhibitors

J. Madwed, R. Fryer, M. Kashem, 2012, Journal of Pharmacology and Experimental Therapeutics.

A study of the Chamaeleon dark cloud and T-association – I. Extinction, distance and membership

A. P. Oates, F. Watson, D. Whittet, 1987 .

Substituted pyrazoles as novel sEH antagonist: investigation of key binding interactions within the catalytic domain.

J. Proudfoot, U. Patel, Rajiv Sharma, 2010, Bioorganic & medicinal chemistry letters.

Non-steroidal dissociated glucocorticoid agonists: indoles as A-ring mimetics and function-regulating pharmacophores.

T. Gilmore, J. Regan, C. Torcellini, 2011, Bioorganic & medicinal chemistry letters.

Trifluoromethyl group as a pharmacophore: effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand.

G. Nabozny, Ljiljana Žuvela-Jelaska, D. Kuzmich, 2005, Bioorganic & medicinal chemistry letters.

Practical synthesis of 1,3-diaryl-5-alkylpyrazoles by a highly regioselective N-arylation of 3,5-disubstituted pyrazoles with 4-fluoronitrobenzene

J. Proudfoot, K. Grozinger, Xiaojun Wang, 2000 .

New modifications to the area of pyrazole-naphthyl urea based p38 MAP kinase inhibitors that bind to the adenine/ATP site.

K. Qian, J. Madwed, C. Pargellis, 2007, Bioorganic & medicinal chemistry letters.

Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria

F. Gamo, E. Fang, Yen-Liang Chen, 2022, Journal of medicinal chemistry.

Identification of a potent sodium hydrogen exchanger isoform 1 (NHE1) inhibitor with a suitable profile for chronic dosing and demonstrated cardioprotective effects in a preclinical model of myocardial infarction in the rat.

J. Madwed, E. Hickey, M. Karmazyn, 2012, Journal of medicinal chemistry.

Identification of dissociated non-steroidal glucocorticoid receptor agonists.

J. Proudfoot, P. Reilly, Alison J Kukulka, 2007, Bioorganic & medicinal chemistry letters.

Indole RSK inhibitors. Part 1: discovery and initial SAR.

J. Madwed, M. Kashem, R. Snow, 2012, Bioorganic & medicinal chemistry letters.

Indole RSK inhibitors. Part 2: optimization of cell potency and kinase selectivity.

M. Kashem, R. Snow, A. Swinamer, 2012, Bioorganic & medicinal chemistry letters.

Ligands for the tyrosine kinase p56lck SH2 domain: discovery of potent dipeptide derivatives with monocharged, nonhydrolyzable phosphate replacements.

J. Proudfoot, L. Tong, E. Hickey, 1999, Journal of medicinal chemistry.

Indole RSK inhibitors. Part 1: discovery and initial SAR.

J. Madwed, M. Kashem, R. Snow, 2012, Bioorganic & medicinal chemistry letters.