R. Kroe

发表

Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors.

K. Qian, J. Madwed, C. Pargellis, 2009, Bioorganic & medicinal chemistry letters.

Discovery and design of benzimidazolone based inhibitors of p38 MAP kinase.

M. Hao, K. Qian, N. Moss, 2006, Bioorganic & medicinal chemistry letters.

Agonist versus antagonist induce distinct thermodynamic modes of co-factor binding to the glucocorticoid receptor.

Elda Gautschi, N. Farrow, C. A. Grygon, 2007, Biophysical chemistry.

Catalysis and Function of the p38α·MK2a Signaling Complex

C. Pargellis, B. Werneburg, S. Lukas, 2004 .

Applications of fluorescence detected sedimentation I Studying the thermodynamic impact of valence in non-ideal solutions II High affinity interactions and biological media

R. Kroe, 2005 .

Assembly of major histocompatibility complex (MHC) class II transcription factors: association and promoter recognition of RFX proteins.

R. Ingraham, C. A. Grygon, R. Kroe, 2004, Biochemistry.

Discovery and design of benzimidazolone based inhibitors of p38 MAP kinase.

M. Hao, K. Qian, N. Moss, 2006, Bioorganic & medicinal chemistry letters.

Structure-activity relationships of the p38alpha MAP kinase inhibitor 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796).

J. Madwed, C. Pargellis, P. Cirillo, 2003, Journal of medicinal chemistry.

New modifications to the area of pyrazole-naphthyl urea based p38 MAP kinase inhibitors that bind to the adenine/ATP site.

K. Qian, J. Madwed, C. Pargellis, 2007, Bioorganic & medicinal chemistry letters.

NUTS and BOLTS: applications of fluorescence-detected sedimentation.

T. Laue, Rachel R. Kroe, R. Kroe, 2009, Analytical biochemistry.

Discovery and optimization of p38 inhibitors via computer-assisted drug design.

Angela Berry, Jinhua J. Song, Ming-Hong Hao, 2007, Journal of medicinal chemistry.

Thermal denaturation: a method to rank slow binding, high-affinity P38alpha MAP kinase inhibitors.

C. Pargellis, J. Regan, G. W. Peet, 2003, Journal of medicinal chemistry.

Catalysis and function of the p38 alpha.MK2a signaling complex.

C. Pargellis, B. Werneburg, S. Lukas, 2004, Biochemistry.

Small molecule LFA-1 antagonists compete with an anti-LFA-1 monoclonal antibody for binding to the CD11a I domain: development of a flow-cytometry-based receptor occupancy assay.

P. Reilly, J. Woska, D. Jeanfavre, 2003, Journal of immunological methods.

Discovery and characterization of a substrate selective p38alpha inhibitor.

C. Pargellis, B. Werneburg, S. Lukas, 2004, Biochemistry.

Structure-based design and subsequent optimization of 2-tolyl-(1,2,3-triazol-1-yl-4-carboxamide) inhibitors of p38 MAP kinase.

M. Hao, K. Qian, C. Pargellis, 2008, Bioorganic & medicinal chemistry letters.