T. Kawasuji

发表

High-power injection lock laser platform for ArF dry/wet lithography

Yoshihiro Watanabe, Toshihiro Ito, Tamotsu Abe, 2005, SPIE Advanced Lithography.

Carbamoyl pyridone HIV-1 integrase inhibitors. 1. Molecular design and establishment of an advanced two-metal binding pharmacophore.

T. Seki, T. Fujiwara, T. Yoshinaga, 2012, Journal of medicinal chemistry.

A platform for designing HIV integrase inhibitors. Part 1: 2-hydroxy-3-heteroaryl acrylic acid derivatives as novel HIV integrase inhibitor and modeling of hydrophilic and hydrophobic pharmacophores.

T. Fujiwara, T. Yoshinaga, R. Kiyama, 2006, Bioorganic & medicinal chemistry.

Synthesis and evaluation of 7-substituted 4-aminoquinoline analogs for antimalarial activity

J. Derisi, R. Guy, David J Lowes, 2013 .

Carbamoyl pyridone HIV-1 integrase inhibitors. 2. Bi- and tricyclic derivatives result in superior antiviral and pharmacokinetic profiles.

E. Garvey, T. Seki, T. Fujiwara, 2013, Journal of medicinal chemistry.

Enantioselective syntheses of d-erythro-sphingosine and phytosphingosine from simple achiral aldehydes using catalytic asymmetric aldol reactions as key steps

T. Kawasuji, Takaomi Hayashi, S. Kobayashi, 1994 .

3-Hydroxy-1,5-dihydro-pyrrol-2-one derivatives as advanced inhibitors of HIV integrase.

T. Fujiwara, T. Yoshinaga, R. Kiyama, 2007, Bioorganic & medicinal chemistry.

A New Synthetic Route to Monosaccharides from Simple Achiral Compounds By Using a Catalytic Asymmetric Aldol Reaction as a Key Step

S. Kobayashi, T. Kawasuji, 1993 .

1,2-Asymmetric induction in the SN2'-allylation of organocopper and organozinc reagents

E. Nakamura, T. Kawasuji, M. Arai, 1993 .

3‐Hydroxy‐1,5‐dihydro‐pyrrol‐2‐one Derivatives (IV) as Advanced Inhibitors of HIV Integrase.

T. Fujiwara, T. Yoshinaga, R. Kiyama, 2007 .

A platform for designing HIV integrase inhibitors. Part 2: a two-metal binding model as a potential mechanism of HIV integrase inhibitors.

Akihiko Sato, T. Fujiwara, T. Yoshinaga, 2006, Bioorganic & medicinal chemistry.

Anti-selective asymmetric aldol reactions. Enantioselective synthesis of anti-αβ-dihydroxy phenyl ester derivatives

T. Kawasuji, S. Kobayashi, 1994 .

A Novel Chiral Catalyst System, Tin(II) Triflate, a Chiral Diamine, and Tin(II) Oxide, in Asymmetric Aldol Reactions

N. Mori, T. Kawasuji, S. Kobayashi, 1994 .

A New Synthetic Route to Monosaccharides from Simple Achiral Compounds by Using a Catalytic Asymmetric Aldol Reaction as a Key Step.

S. Kobayashi, T. Kawasuji, 1994 .

SN2′-Regio- and Diastereoselective Allylation of Organozinc Reagents

E. Nakamura, T. Kawasuji, M. Arai, 1993 .

Synthesis and antiviral activity of 7-benzyl-4-hydroxy-1,5-naphthyridin-2(1H)-one HIV integrase inhibitors.

E. Garvey, S. Foster, T. Fujiwara, 2009, Journal of medicinal chemistry.

Dolutegravir Interactions with HIV-1 Integrase-DNA: Structural Rationale for Drug Resistance and Dissociation Kinetics

Kazunari Hattori, R. Nolte, T. Yoshinaga, 2013, PloS one.

In Vitro Antiretroviral Properties of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor

Shigeru Miki, Akihiko Sato, Kevin W. Brown, 2010, Antimicrobial Agents and Chemotherapy.

Antiviral Characteristics of GSK1265744, an HIV Integrase Inhibitor Dosed Orally or by Long-Acting Injection

E. Garvey, T. Seki, T. Fujiwara, 2014, Antimicrobial Agents and Chemotherapy.

Naphthyridinone (NTD) integrase inhibitors 4. Investigating N1 acetamide substituent effects with C3 amide groups.

E. Garvey, S. Foster, T. Fujiwara, 2014, Bioorganic & medicinal chemistry letters.

Naphthyridinone (NTD) integrase inhibitors: N1 protio and methyl combination substituent effects with C3 amide groups.

E. Garvey, S. Foster, T. Fujiwara, 2013, Bioorganic & medicinal chemistry letters.

Combining symmetry elements results in potent naphthyridinone (NTD) HIV-1 integrase inhibitors.

E. Garvey, S. Foster, T. Fujiwara, 2011, Bioorganic & medicinal chemistry letters.

Carbamoyl pyridone HIV-1 integrase inhibitors 3. A diastereomeric approach to chiral nonracemic tricyclic ring systems and the discovery of dolutegravir (S/GSK1349572) and (S/GSK1265744).

E. Garvey, T. Seki, S. Foster, 2013, Journal of medicinal chemistry.

Discovery of Tricyclic HIV-1 Integrase-LEDGF/p75 Allosteric Inhibitors by Intramolecular Direct Arylation Reaction.

T. Seki, T. Yoshinaga, T. Akiyama, 2022, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of 7-substituted 4-aminoquinoline analogues for antimalarial activity.

J. Derisi, R. Guy, David J Lowes, 2011, Journal of medicinal chemistry.

Discovery of novel HIV-1 integrase-LEDGF/p75 allosteric inhibitors based on a pyridine scaffold forming an intramolecular hydrogen bond.

T. Seki, T. Iwaki, T. Yoshinaga, 2020, Bioorganic & medicinal chemistry letters.

Discovery of novel integrase-LEDGF/p75 allosteric inhibitors based on a benzene scaffold.

T. Seki, T. Iwaki, T. Yoshinaga, 2020, Bioorganic & medicinal chemistry.