Xudong Sun

3D-QSAR (CoMFA, CoMSIA), molecular docking and molecular dynamics simulations study of 6-aryl-5-cyano-pyrimidine derivatives to explore the structure requirements of LSD1 inhibitors.

Lina Ding, Hong-min Liu, Jing Yang, 2017, Bioorganic & medicinal chemistry letters.

Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation.

Hong-min Liu, Xiaoyu Zhai, Dandan Shen, 2017, European journal of medicinal chemistry.

Identifying the novel inhibitors of lysine-specific demethylase 1 (LSD1) combining pharmacophore-based and structure-based virtual screening

Wen-en Zhao, Lina Ding, Hong-min Liu, 2018, Journal of biomolecular structure & dynamics.

Novel formulation of c-di-GMP with cytidinyl/cationic lipid reverses T cell exhaustion and activates stronger anti-tumor immunity

Z. Guan, H. Jin, H. Dai, 2022, Theranostics.

Probing the binding mode and unbinding mechanism of LSD1 inhibitors by combined computational methods.

Lina Ding, Hong-min Liu, Xudong Sun, 2018, Physical chemistry chemical physics : PCCP.

Development of the triazole-fused pyrimidine derivatives as highly potent and reversible inhibitors of histone lysine specific demethylase 1 (LSD1/KDM1A)

Lina Ding, Liying Ma, Hongmin Liu, 2019, Acta pharmaceutica Sinica. B.

Probing the binding mechanism of substituted pyridine derivatives as effective and selective lysine-specific demethylase 1 inhibitors using 3D-QSAR, molecular docking and molecular dynamics simulations

Lina Ding, Hong-min Liu, Jing Yang, 2018, Journal of biomolecular structure & dynamics.

Cyclic diguanylate analogues: Facile synthesis, STING binding mode and anti-tumor immunity delivered by cytidinyl/cationic lipid.

Quanxin Wang, Z. Guan, Zhenjun Yang, 2022, European journal of medicinal chemistry.