Martina Gobec

发表

Discovery of Immunoproteasome Inhibitors Using Large-Scale Covalent Virtual Screening

G. Keserű, G. Ferenczy, S. Gobec, 2019, Molecules.

Glycosaminoglycans as Tools to Decipher the Platelet Tumor Cell Interaction: A Focus on P-Selectin

G. Bendas, A. Naggi, U. Barash, 2020, Molecules.

Discovery of Novel Small-Molecule Compounds with Selective Cytotoxicity for Burkitt’s Lymphoma Cells Using 3D Ligand-Based Virtual Screening

I. Mlinarič-Raščan, S. Gobec, Izidor Sosič, 2014, Molecules.

EP4 receptor signalling in immature B cells involves cAMP and NF‐κB dependent pathways

I. Mlinarič-Raščan, M. Prijatelj, T. Celhar, 2012, The Journal of pharmacy and pharmacology.

Inhibition of O-GlcNAc Transferase Alters the Differentiation and Maturation Process of Human Monocyte Derived Dendritic Cells

M. Anderluh, Martina Gobec, Matjaž Weiss, 2021, Cells.

New Quinolinone O-GlcNAc Transferase Inhibitors Based on Fragment Growth

R. Pieters, M. Anderluh, T. Tomašič, 2021, Frontiers in Chemistry.

Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments

G. Keserű, B. Vértessy, A. Perczel, 2020, ChemBioChem.

Development of an in-vivo active reversible butyrylcholinesterase inhibitor

J. Kos, B. Malawska, M. Perše, 2016, Scientific Reports.

Structure-Activity Relationships of Novel Tryptamine-Based Inhibitors of Bacterial Transglycosylase.

E. Breukink, M. Anderluh, M. Terrak, 2015, Journal of medicinal chemistry.

Environmental contamination status with common ingredients of household and personal care products exhibiting endocrine-disrupting potential

Martina Gobec, Ž. Jakopin, Veronika Klančič, 2022, Environmental Science and Pollution Research.

Novel N-amidinopiperidine-based proteasome inhibitor preserves dendritic cell functionality and rescues their Th1-polarizing capacity in Ramos-conditioned tumor environment

I. Mlinarič-Raščan, U. Švajger, Aleš Obreza, 2014, Cancer Immunology, Immunotherapy.

Structural features and functional activities of benzimidazoles as NOD2 antagonists.

E. Corsini, I. Mlinarič-Raščan, Martina Gobec, 2020, European journal of medicinal chemistry.

Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2.

I. Mlinarič-Raščan, M. Anderluh, T. Tomašič, 2016, Bioorganic & medicinal chemistry.

In Silico Discovery and Optimisation of a Novel Structural Class of Hsp90 C-Terminal Domain Inhibitors

T. Tomašič, Martina Gobec, Živa Zajec, 2022, Biomolecules.

Structural requirements of acylated Gly-l-Ala-d-Glu analogs for activation of the innate immune receptor NOD2.

I. Mlinarič-Raščan, M. Dolenc, Martina Gobec, 2016, European journal of medicinal chemistry.

Editorial: The Role of Platelets in Cancer Progression and Malignancy

A. Bauer, Martina Gobec, M. Schlesinger, 2021, Frontiers in Oncology.

EP4 receptor agonist L-902688 augments cytotoxic activities of ibrutinib, idelalisib, and venetoclax against chronic lymphocytic leukemia cells.

I. Mlinarič-Raščan, Martina Gobec, Ž. Jakopin, 2020, Biochemical pharmacology.

Fragment-Sized and Bidentate (Immuno)Proteasome Inhibitors Derived from Cysteine and Threonine Targeting Warheads

G. Keserű, P. Ábrányi‐Balogh, G. Ferenczy, 2021, Cells.

Chemo-sensitizing effects of EP4 receptor-induced inactivation of nuclear factor-κB.

I. Mlinarič-Raščan, J. Delic, M. Prijatelj, 2014, European journal of pharmacology.

Discovery of selective fragment-sized immunoproteasome inhibitors.

G. Keserű, P. Ábrányi‐Balogh, G. Ferenczy, 2021, European journal of medicinal chemistry.

Immunomodulatory properties of novel nucleotide oligomerization domain 2 (nod2) agonistic desmuramyldipeptides.

I. Mlinarič-Raščan, M. Sollner Dolenc, Martina Gobec, 2012, Journal of medicinal chemistry.

Intracellular Hydrolysis of Small-Molecule O-Linked N-Acetylglucosamine Transferase Inhibitors Differs among Cells and Is Not Required for Its Inhibition

R. Pieters, S. Pajk, M. Anderluh, 2020, Molecules.

Environmental contamination status with common ingredients of household and personal care products exhibiting endocrine-disrupting potential

Martina Gobec, Ž. Jakopin, Veronika Klančič, 2022, Environmental Science and Pollution Research.

Antimicrobial activity and cytotoxicity of some 2-amino-5-alkylidene-thiazol-4-ones

M. Anderluh, M. Jukič, A. Šmelcerović, 2013, Molecular Diversity.

Structural characterization and biological evaluation of a clioquinol-ruthenium complex with copper-independent antileukaemic activity.

I. Mlinarič-Raščan, I. Turel, S. Gobec, 2014, Dalton transactions.

Assessment of tractable cysteines by covalent fragments screening.

S. Grdadolnik, G. Keserű, B. Vértessy, 2020, Chembiochem : a European journal of chemical biology.

Antimicrobial activity and cytotoxicity of some 2-amino-5-alkylidene-thiazol-4-ones

M. Anderluh, A. Šmelcerović, Martina Gobec, 2013, Molecular Diversity.

Design, synthesis and biological evaluation of novel desmuramyldipeptide analogs.

E. Corsini, I. Mlinarič-Raščan, M. Dolenc, 2011, European journal of medicinal chemistry.

Synthesis of conformationally constrained γ-D-glutamyl-meso-diaminopimelic acid derivatives as ligands of nucleotide-binding oligomerization domain protein 1 (Nod1).

I. Mlinarič-Raščan, M. Sollner Dolenc, Martina Gobec, 2013, European journal of medicinal chemistry.

Structural Fine-Tuning of Desmuramylpeptide NOD2 Agonists Defines Their In Vivo Adjuvant Activity

J. Plavec, I. Mlinarič-Raščan, S. Pajk, 2021, Journal of medicinal chemistry.

Halogenated ingredients of household and personal care products as emerging endocrine disruptors.

Martina Gobec, Ž. Jakopin, Veronika Klančič, 2022, Chemosphere.

Pyridylethanol(phenylethyl)amines are non-azole, highly selective Candida albicans sterol 14α-demethylase inhibitors.

D. Rozman, M. Soković, Izidor Sosič, 2020, Bioorganic chemistry.

Antioxidant and anti-inflammatory properties of 1,2,4-oxadiazole analogs of resveratrol.

I. Mlinarič-Raščan, M. Dolenc, T. Tomašič, 2015, Chemico-biological interactions.

Characterization of human lymphoblastoid cell lines as a novel in vitro test system to predict the immunotoxicity of xenobiotics.

D. Gurwitz, I. Mlinarič-Raščan, Martina Gobec, 2015, Toxicology letters.

Another structural correction for 1‐oxo‐1H‐phenalene‐2,3‐dicarbonitriles: Synthesis of a potent BCL‐2 inhibiting 7‐phenoxy derivative

M. Gütschow, G. Bendas, Izidor Sosič, 2021, Archiv der Pharmazie.

Molecular docking revealed potential disruptors of glucocorticoid receptor-dependent reporter gene expression.

M. Sollner Dolenc, K. Kolšek, Martina Gobec, 2014, Toxicology letters.

Optimisation of pyrazolo[1,5-a]pyrimidin-7(4H)-one derivatives as novel Hsp90 C-terminal domain inhibitors against Ewing sarcoma.

M. Distel, T. Tomašič, Martina Gobec, 2022, Bioorganic chemistry.

Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors

T. Tomašič, Nace Zidar, L. P. Mašič, 2021, Pharmaceutics.

Discovery of Nanomolar Desmuramylpeptide Agonists of the Innate Immune Receptor Nucleotide-Binding Oligomerization Domain-Containing Protein 2 (NOD2) Possessing Immunostimulatory Properties.

I. Mlinarič-Raščan, M. Anderluh, T. Tomašič, 2018, Journal of medicinal chemistry.

Nonpeptidic Selective Inhibitors of the Chymotrypsin-Like (β5 i) Subunit of the Immunoproteasome.

Janez Konc, D. Janežič, I. Mlinarič-Raščan, 2016, Angewandte Chemie.

Nanofibers with genotyped Bacillus strains exhibiting antibacterial and immunomodulatory activity.

Špela Zupančič, P. Kocbek, J. Kristl, 2023, Journal of controlled release : official journal of the Controlled Release Society.

A focused structure-activity relationship study of psoralen-based immunoproteasome inhibitors.

Janez Mravljak, S. Gobec, Izidor Sosič, 2019, MedChemComm.

Screening of bisphenol A, triclosan and paraben analogues as modulators of the glucocorticoid and androgen receptor activities.

M. Sollner Dolenc, K. Kolšek, Martina Gobec, 2015, Toxicology in vitro : an international journal published in association with BIBRA.

Synthesis and Biochemical Evaluation of Warhead-Decorated Psoralens as (Immuno)Proteasome Inhibitors

Janez Mravljak, S. Gobec, Izidor Sosič, 2021, Molecules.

Branched α-D-mannopyranosides : a new class of potent FimH antagonists

B. Ernst, M. Anderluh, T. Tomašič, 2014 .

Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2.

I. Mlinarič-Raščan, M. Anderluh, T. Tomašič, 2016, Bioorganic & medicinal chemistry.

Nonpeptidic Selective Inhibitors of the Chymotrypsin-Like (β5 i) Subunit of the Immunoproteasome.

Janez Konc, D. Janežič, I. Mlinarič-Raščan, 2016, Angewandte Chemie.

Selective Cytotoxicity of Amidinopiperidine Based Compounds Towards Burkitt’s Lymphoma Cells Involves Proteasome Inhibition

I. Mlinarič-Raščan, S. Gobec, Aleš Obreza, 2012, PloS one.

In vitro investigation of immunomodulatory activities of selected UV-filters.

Veronika Weiss, Martina Gobec, Ž. Jakopin, 2023, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

New Class of Hsp90 C-Terminal Domain Inhibitors with Anti-tumor Properties against Triple-Negative Breast Cancer.

T. Tomašič, Martina Gobec, S. Golič Grdadolnik, 2024, Journal of medicinal chemistry.

Modulating Immune Responses: The Double-Edged Sword of Platelet CD40L.

Martina Gobec, M. Schlesinger, Gerd Bendas, 2024, Seminars in thrombosis and hemostasis.

Discovery of 2,3-Diaminoindole Derivatives as a Novel Class of NOD Antagonists.

A. Carotenuto, L. Marinelli, F. S. Di Leva, 2024, Journal of medicinal chemistry.

Design and synthesis of amino-substituted N-arylpiperidinyl-based inhibitors of the (immuno)proteasome

Aleš Obreza, Martina Gobec, A. Baumgartner, 2023, Acta pharmaceutica.