L. Hughes

发表

Real time Raman imaging to understand dissolution performance of amorphous solid dispersions.

J. Aylott, S. Wren, Francesco Tres, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Dissolution of Bicalutamide Single Crystals in Aqueous Solution: Significance of Evolving Topography in Accelerating Face-Specific Kinetics

P. Unwin, Faduma M. Maddar, S. Wren, 2017 .

Face-Discriminating Dissolution Kinetics of Furosemide Single Crystals: In Situ Three-Dimensional Multi-Microscopy and Modeling

M. Ward, P. Unwin, Faduma M. Maddar, 2016 .

Monitoring the Dissolution Mechanisms of Amorphous Bicalutamide Solid Dispersions via Real-Time Raman Mapping.

J. Aylott, S. Wren, Francesco Tres, 2015, Molecular pharmaceutics.

A curious case of dynamic disorder in pyrrolidine rings elucidated by NMR crystallography.

Steven P. Brown, Sten O. Nilsson Lill, S. N. Nilsson Lill, 2020, Chemical communications.

Improving Confidence in Crystal Structure Solutions Using NMR Crystallography: The Case of β-Piroxicam

Steven P. Brown, J. Yates, P. Hodgkinson, 2018 .

Structural characterisation of amorphous solid dispersions via metropolis matrix factorisation of pair distribution function data.

A. Goodwin, J. McCabe, L. Hughes, 2019, Chemical communications.

Indomethacin-Kollidon VA64 Extrudates: A Mechanistic Study of pH-Dependent Controlled Release.

J. Aylott, S. Wren, Francesco Tres, 2016, Molecular pharmaceutics.

Investigating the Dissolution Performance of Amorphous Solid Dispersions Using Magnetic Resonance Imaging and Proton NMR

J. Aylott, S. Coombes, S. Wren, 2015, Molecules.

Conformations in Solution and in Solid-State Polymorphs: Correlating Experimental and Calculated NMR Chemical Shifts for Tolfenamic Acid.

Steven P. Brown, C. Blundell, J. Carson, 2020, The journal of physical chemistry. A.

Combining X-ray and NMR Crystallography to Explore the Crystallographic Disorder in Salbutamol Oxalate

Steven P. Brown, Chick C. Wilson, Helen P. Wheatcroft, 2022, Crystal growth & design.

Investigating discrepancies between experimental solid-state NMR and GIPAW calculation: NC-N 13C and OH⋯O 1H chemical shifts in pyridinium fumarates and their cocrystals.

Steven P. Brown, R. Walton, David Walker, 2020, Solid state nuclear magnetic resonance.

5-amino-2-methylpyridinium hydrogen fumarate: an XRD and NMR crystallography analysis.

Steven P. Brown, R. Walton, P. Sidebottom, 2020, Magnetic resonance in chemistry : MRC.

The global characterisation of a drug-dendrimer conjugate - PEGylated poly-lysine dendrimer.

D. Buttar, Tony W. T. Bristow, N. Mahmoudi, 2022, Journal of pharmaceutical sciences.

Effect of encapsulating a pseudo-decapeptide containing arginine on PLGA: a solid-state NMR study.

Y. Khimyak, A. Saiani, Jean-Baptiste Guilbaud, 2010, Journal of pharmaceutical sciences.

Characterization of Amorphous Solid Dispersions and Identification of Low Levels of Crystallinity by Transmission Electron Microscopy.

N. Hondow, Andy P. Brown, R. Drummond-Brydson, 2021, Molecular pharmaceutics.

Taming the dynamics in a pharmaceutical by cocrystallization: investigating the impact of the coformer by solid-state NMR

Sten O. Nilsson Lill, S. N. Nilsson Lill, Józef R. Lewandowski, 2021, CrystEngComm.

Mechanistic insights into the dissolution of spray-dried amorphous solid dispersions.

Gavin K Reynolds, Jonathan Booth, G. Reynolds, 2012, Journal of pharmaceutical sciences.

Proton NMR: a new tool for understanding dissolution.

S. Coombes, S. Wren, A. Phillips, 2014, Analytical chemistry.

An XRD and NMR crystallographic investigation of the structure of 2,6-lutidinium hydrogen fumarate

R. Walton, David Walker, P. Sidebottom, 2019, CrystEngComm.

NMR and thermal studies for the characterization of mass transport and phase separation in paracetamol/copovidone hot-melt extrusion formulations.

S. Wren, M. Mantle, J. McCabe, 2020, Molecular pharmaceutics.

Probing intermolecular hydrogen bonding in sibenadet hydrochloride polymorphs by high-resolution (1) H double-quantum solid-state NMR spectroscopy.

C. Pickard, J. Burley, L. Hughes, 2012, Journal of pharmaceutical sciences.

Mechanistic understanding of the link between Sodium Starch Glycolate properties and the performance of tablets made by wet granulation.

S. Wren, L. Hughes, F. Alhusban, 2017, International journal of pharmaceutics.

Toward Developing a Predictive Approach To Assess Electron Beam Instability during Transmission Electron Microscopy of Drug Molecules.

N. Hondow, R. Brydson, Andy P. Brown, 2018, Molecular pharmaceutics.

A toolbox for improving the workflow of NMR crystallography.

Sten O. Nilsson Lill, S. N. Nilsson Lill, L. Hughes, 2021, Solid state nuclear magnetic resonance.

Multi-linear Regression Model to Predict the Electron Stability of Poorly Soluble Active Pharmaceutical Ingredients

N. Hondow, R. Brydson, Andy P. Brown, 2017, Microscopy and Microanalysis.

Monitoring apoptosis in intact cells by high‐resolution magic angle spinning 1H NMR spectroscopy

J. Griffin, J. Bothwell, S. Wren, 2021, NMR in biomedicine.

Quantitative ultra-fast MRI of HPMC swelling and dissolution.

L. Gladden, M. Mantle, L. Hughes, 2010, Journal of pharmaceutical sciences.

Measuring the rate of in-vitro drug release from polymeric nanoparticles by 19F solution state NMR spectroscopy.

S. Wren, L. Hughes, Ian Jones, 2021, Journal of pharmaceutical sciences.

Mechanistic insights into the dissolution of spray-dried amorphous solid dispersions.

G. Reynolds, S. Wren, J. Booth, 2012, Journal of pharmaceutical sciences.

Polymorph Identification for Flexible Molecules: Linear Regression Analysis of Experimental and Calculated Solution- and Solid-State NMR Data

L. Hughes, H. Blade, Ben P. Tatman, 2024, The journal of physical chemistry. A.

Structure of polymeric nanoparticles encapsulating a drug – pamoic acid ion pair by scanning transmission electron microscopy

S. Collins, N. Hondow, L. Hughes, 2023, Heliyon.