P. Giri

发表

Preclinical evaluation of saroglitazar magnesium, a dual PPAR-α/γ agonist for treatment of dyslipidemia and metabolic disorders

H. Patel, P. Patel, Nirav Modi, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Incurred sample reanalysis in drug discovery bioanalysis.

N. Srinivas, P. Giri, Nirmal Patel, 2018, Biomedical chromatography : BMC.

Evaluation of novel TGR5 agonist in combination with Sitagliptin for possible treatment of type 2 diabetes.

Suresh R. Giri, Mukul R Jain, Sameer Agarwal, 2018, Bioorganic & medicinal chemistry letters.

Assessment of the in vitro cytochrome P450 (CYP) inhibition potential of ZYTP1, a novel poly (ADP-ribose) polymerase inhibitor

N. Srinivas, P. Giri, Sanjay Singh, 2019, Xenobiotica; the fate of foreign compounds in biological systems.

Relevance of preclinical rodent pharmacokinetics in the selection of a companion antibiotic for combining with beta-lactamase inhibitor

N. Srinivas, Mukul R Jain, P. Giri, 2019, Xenobiotica; the fate of foreign compounds in biological systems.

Review of Clinical Pharmacokinetics of Avibactam, A Newly Approved non-β lactam β-lactamase Inhibitor Drug, In Combination Use With Ceftazidime

H. Patel, N. Srinivas, P. Giri, 2018, Drug Research.

Evaluation of In Vitro Cytochrome P450 Inhibition and In Vitro Fate of Structurally Diverse N-Oxide Metabolites: Case Studies with Clozapine, Levofloxacin, Roflumilast, Voriconazole and Zopiclone

H. Patel, N. Srinivas, P. Giri, 2017, European Journal of Drug Metabolism and Pharmacokinetics.

Consequences of daily corticosteroid dosing with or without pre-treatment with quinidine on the in vivo cytochrome P450 2D (CYP2D) enzyme in rats: effect on O-demethylation activity of dextromethorphan and expression levels of CYP2D1 mRNA

N. Srinivas, K. Lad, Hiren M Patel, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Use of Cocktail Probe Drugs for Indexing Cytochrome P450 Enzymes in Clinical Pharmacology Studies - Review of Case Studies.

H. Patel, N. Srinivas, P. Giri, 2019, Drug metabolism letters.

Simultaneous determination of sacubitrilat and fimasartan in rat plasma by a triple quad LC-MS/MS method utilizing electrospray ionization in a positive mode.

Mukul R Jain, P. Giri, Vipul Joshi, 2020, Biomedical chromatography : BMC.

Discovery of 1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-ones based novel, potent and PI3Kδ selective inhibitors.

D. Bandyopadhyay, R. Bahekar, Dipam N Patel, 2019, Bioorganic & medicinal chemistry letters.

ZYBT1, a potent, irreversible Bruton’s Tyrosine Kinase (BTK) inhibitor that inhibits the C481S BTK with profound efficacy against arthritis and cancer

D. Bandyopadhyay, Rajiv Sharma, N. Srinivas, 2020, Pharmacology research & perspectives.

Review of the bioanalytical methods for the determination of methotrexate and its metabolites in in vitro, preclinical and clinical studies: Case studies and perspectives.

Muzeeb Syed, H. Patel, A. Ghoghari, 2017, Biomedical chromatography : BMC.

Discovery of novel, potent and orally efficacious inhibitor of neutral amino acid transporter B0AT1 (SLC6A19).

Sanjay Kumar, D. Bandyopadhyay, Rajiv Sharma, 2021, Bioorganic & medicinal chemistry letters.

Identification of a novel orally bioavailable NLRP3 inflammasome inhibitor

D. Bandyopadhyay, Rajiv Sharma, Mukul R Jain, 2020, Bioorganic & Medicinal Chemistry Letters.

Lack of inhibition of CYP2C8 by saroglitazar magnesium: In vivo assessment using montelukast, rosiglitazone, pioglitazone, repaglinide and paclitaxel as victim drugs in Wistar rats

N. Srinivas, Mukul R Jain, P. Giri, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Nonclinical Pharmacokinetic Evaluation of Desidustat: a Novel Prolyl Hydroxylase Inhibitor for the Treatment of Anemia

H. Patel, P. Patel, Nirav Modi, 2022, European Journal of Drug Metabolism and Pharmacokinetics.

Discovery of N-Cyano-sulfoximineurea Derivatives as Potent and Orally Bioavailable NLRP3 Inflammasome Inhibitors.

D. Bandyopadhyay, Rajiv Sharma, P. Iyer, 2020, ACS medicinal chemistry letters.

Identification and preclinical characterization of a novel and potent poly (ADP-ribose) polymerase (PARP) inhibitor ZYTP1

H. Patel, P. Patel, N. Srinivas, 2018, Cancer Chemotherapy and Pharmacology.

Review of Pharmacokinetic Data of Different Drug Classes in Goto-Kakizaki Rats, a Non-obese Model for Type 2 Diabetes Mellitus: Case Studies and Perspectives

H. Patel, N. Srinivas, P. Giri, 2017, European Journal of Drug Metabolism and Pharmacokinetics.

Impact of collagen-induced arthritis on the pharmacokinetic disposition of voriconazole, a widely used antifungal agent: in vitro and in vivo investigations in DBA/1J mice

N. Srinivas, Shekhar Kadam, P. Giri, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Optimisation of momelotinib with improved potency and efficacy as pan-JAK inhibitor.

D. Bandyopadhyay, Mukul R Jain, P. Giri, 2022, Bioorganic & Medicinal Chemistry Letters.

Discovery of a Potent and Orally Efficacious TGR5 Receptor Agonist.

H. Patel, Suresh R. Giri, Mukul R Jain, 2016, ACS medicinal chemistry letters.

Discovery of a Potent and Orally E ffi cacious TGR 5 Receptor Agonist

H. Patel, Suresh R. Giri, Mukul R Jain, 2016 .

Opposite effects of acute kidney injury on pharmacokinetics of renally and hepatobiliary excreted drugs

N. Srinivas, P. Giri, Vipul Joshi, 2018 .

In Vitro Drug-Drug Interaction Potential of Sulfoxide and/or Sulfone  Metabolites of Albendazole, Triclabendazole, Aldicarb, Methiocarb, Montelukast and Ziprasidone

N. Srinivas, P. Giri, Nirmal Patel, 2018, Drug metabolism letters.

Sensitive and specific LC-ESI-MS/MS method for determination of ZYDPLA1, a novel long-acting dipeptidyl peptidase 4 inhibitor in rat plasma: An application for toxicokinetic study in rats.

H. Patel, N. Srinivas, R. Bahekar, 2017, Biomedical chromatography : BMC.

Regression modeling strategy for prediction of AUC of evogliptin, a novel dipeptidyl peptidase IV inhibitor in humans, using single dose PK data

N. Srinivas, P. Giri, Shuchi N. Joshi, 2018 .

Identification of an Orally Efficacious GPR40/FFAR1 Receptor Agonist.

D. Bandyopadhyay, Suresh R. Giri, Mukul R Jain, 2016, ACS medicinal chemistry letters.