M. Ogawa

发表

Population pharmacokinetics and exposure-response relationship of a muscarinic receptor antagonist, imidafenacin.

Takafumi Ouchi, S. Nakade, Chihiro Hasegawa, 2013, Drug metabolism and pharmacokinetics.

The prediction of human response to ONO‐4641, a sphingosine 1‐phosphate receptor modulator, from preclinical data based on pharmacokinetic–pharmacodynamic modeling

S. Nakade, Chihiro Hasegawa, T. Ohno, 2010, Biopharmaceutics & drug disposition.

Development and validation of an on-line two-dimensional reversed-phase liquid chromatography-tandem mass spectrometry method for the simultaneous determination of prostaglandins E(2) and F(2alpha) and 13,14-dihydro-15-keto prostaglandin F(2alpha) levels in human plasma.

J. Komaba, Yoshitaka Hashimoto, S. Nakade, 2009, Biomedical chromatography : BMC.

Design and synthesis of a highly selective EP2-receptor agonist.

M. Toda, S. Ohuchida, T. Maruyama, 2001, Bioorganic & medicinal chemistry letters.

Modeling and simulation of bone mineral density response from a phase 2 study of ONO‐5334, a new cathepsin K inhibitor, to support dose selection in osteoporosis

I. Ieiri, H. Kastrissios, J. Monteleone, 2014, Journal of clinical pharmacology.

Population pharmacokinetic and pharmacodynamic modeling of different formulations of ONO‐5334, cathepsin K inhibitor, in Caucasian and Japanese postmenopausal females

I. Ieiri, Chihiro Hasegawa, T. Ohno, 2014, Journal of clinical pharmacology.

In vitro metabolism and inhibitory effects of pranlukast in human liver microsomes.

K. Nunoya, K. Yoneda, S. Nakade, 2009, Biological & pharmaceutical bulletin.

Development of a highly selective EP2-receptor agonist. Part 1: identification of 16-hydroxy-17,17-trimethylene PGE2 derivatives.

M. Toda, S. Ohuchida, T. Maruyama, 2002, Bioorganic & medicinal chemistry.

Evaluation of Hepatic Disposition of Paroxetine Using Sandwich-Cultured Rat and Human Hepatocytes

I. Tamai, M. Okada, K. Nunoya, 2013, Drug Metabolism and Disposition.

DMD049817 735..743

I. Tamai, M. Okada, K. Nunoya, 2013 .

Mathematical modeling of the in vitro hepatic disposition of mycophenolic acid and its glucuronide in sandwich-cultured human hepatocytes.

T. Nakanishi, I. Tamai, M. Ogawa, 2014, Molecular pharmaceutics.

Modeling approach for multiple transporters-mediated drug-drug interactions in sandwich-cultured human hepatocytes: effect of cyclosporin A on hepatic disposition of mycophenolic acid phenyl-glucuronide.

T. Nakanishi, I. Tamai, H. Imawaka, 2015, Drug metabolism and pharmacokinetics.