P. Wright

发表

T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure

Aron Monszpart, S. Harding, J. Gorelik, 2017, Cardiovascular research.

β3-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes

J. Balligand, S. Harding, J. Gorelik, 2020, eLife.

Spatial control of the βAR system in heart failure: the transverse tubule and beyond.

S. Harding, J. Gorelik, A. Lyon, 2013, Cardiovascular research.

High Levels of Circulating Epinephrine Trigger Apical Cardiodepression in a &bgr;2-Adrenergic Receptor/Gi–Dependent Manner: A New Model of Takotsubo Cardiomyopathy

N. Peters, S. Harding, M. Petrou, 2012, Circulation.

Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains

G. Faggian, J. Gorelik, C. Poulet, 2018, Front. Physiol..

Takotsubo cardiomyopathy: the pathophysiology.

A. Lyon, M. Sikkel, Matthew H. Tranter, 2013, Heart failure clinics.

Pathophysiology of Takotsubo Syndrome

A. Lyon, A. Morley-Smith, Matthew H. Tranter, 2014 .

Heart failure leads to altered &bgr;2-adrenoceptor/cyclic adenosine monophosphate dynamics in the sarcolemmal phospholemman/Na,K ATPase microdomain

M. Shattock, J. Gorelik, D. Pavlovic, 2018, Cardiovascular research.

University of Birmingham Heart failure leads to altered 2-adrenoceptor/cAMP dynamics in the sarcolemmal phospholemman/Na,K ATPase microdomain

M. Shattock, J. Gorelik, D. Pavlovic, 2018 .

Heart failure leads to altered beta 2-adrenoceptor / cAMP dynamics in the sarcolemmal phospholemman / Na , K ATPase microdomain

M. Shattock, J. Gorelik, D. Pavlovic, 2017 .

Pathophysiology of takotsubo syndrome: temporal phases of cardiovascular responses to extreme stress.

A. Lyon, A. Morley-Smith, Matthew H. Tranter, 2014, Circulation journal : official journal of the Japanese Circulation Society.

Hyperthermia as a trigger for Takotsubo syndrome in a rat model

S. Harding, E. Omerovic, B. Redfors, 2022, Frontiers in Cardiovascular Medicine.

Studying signal compartmentation in adult cardiomyocytes

J. Gorelik, P. Wright, Aleksandra Judina, 2020, Biochemical Society transactions.

Circulating microRNAs predispose to takotsubo syndrome following high-dose adrenaline exposure

S. Harding, T. Thum, A. Lyon, 2021, Cardiovascular research.

Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling.

Thomas O'Hara, Julia Gorelik, Natalia A Trayanova, 2014, Journal of molecular and cellular cardiology.

Is high-dose catecholamine administration in small animals an appropriate model for takotsubo syndrome? - Reply.

A. Lyon, A. Morley-Smith, Matthew H. Tranter, 2015, Circulation journal : official journal of the Japanese Circulation Society.

Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in β2AR-cAMP Responsiveness in Murine Hearts

M. Zaccolo, G. Faggian, T. Kamp, 2018, Cell reports.

Electrophysiological Remodeling: Cardiac T-Tubules and ß-Adrenoceptors

S. Harding, J. Gorelik, P. Wright, 2021, Cells.

Studying GPCR/cAMP pharmacology from the perspective of cellular structure

J. Gorelik, P. Wright, Sophie Schobesberger, 2015, Front. Pharmacol..

Microtubule-Dependent Mitochondria Alignment Regulates Calcium Release in Response to Nanomechanical Stimulus in Heart Myocytes

M. Lab, J. Gorelik, P. Novak, 2015, Cell reports.

Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cells

D. Klenerman, Y. Korchev, J. Mitchell, 2011, Journal of the Royal Society Interface.

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications

Jordi Villà-Freixa, Peter Sandner, Bernd J. Pichler, 2017, BMC Pharmacology and Toxicology.

FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility

M. Zaccolo, S. Pantano, D. Bers, 2017, Nature Communications.

Approaches to High-Throughput Analysis of Cardiomyocyte Contractility

Steven B Marston, A. J. Francis, K. MacLeod, 2020, Frontiers in Physiology.

The scanning ion conductance microscope for cellular physiology.

M. Lab, J. Gorelik, Anamika Bhargava, 2013, American journal of physiology. Heart and circulatory physiology.

Microtubules regulate cardiomyocyte transversal Young’s modulus

J. Gorelik, P. Novak, J. Sanchez-Alonso, 2020, Proceedings of the National Academy of Sciences.

Ismail living cardiovascular cells high-resolution technology for multi-parametric analysis of Scanning ion conductance microscopy : a convergent

D. Klenerman, Y. Korchev, S. Harding, 2011 .

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications

James C. Campbell, Dong I. Lee, M. Zaccolo, 2017, BMC Pharmacology and Toxicology.

Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cells

D. Klenerman, Y. Korchev, J. Mitchell, 2011, Journal of The Royal Society Interface.

Microtubule-Mediated Regulation of β2AR Translation and Function in Failing Hearts

A. Ivanov, J. Edel, Binoy Paulose Nadappuram, 2023, Circulation research.