David R Spring

发表

Multifunctional supramolecular polymer networks as next-generation consolidants for archaeological wood conservation

Alexandros Koutsioubas, Zarah Walsh, Emma-Rose Janeček, 2014, Proceedings of the National Academy of Sciences.

The discovery of antibacterial agents using diversity-oriented synthesis.

Andreas Bender, David R Spring, Martin Welch, 2009, Chemical communications.

Enriching chemical space with diversity-oriented synthesis.

David R Spring, Gemma L Thomas, Emma E Wyatt, 2006, Current opinion in drug discovery & development.

Rational methods for the selection of diverse screening compounds.

David R Spring, David J Huggins, Ashok R Venkitaraman, 2011, ACS chemical biology.

Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design

Jason C Cole, David R Spring, Richard A. Sykes, 2020, J. Chem. Inf. Model..

Is synthesis the main hurdle for the generation of diversity in compound libraries for screening?

David R Spring, Warren Rjd Galloway, D. Spring, 2009, Expert opinion on drug discovery.

Diversity-oriented synthesis.

David R Spring, Kieron M. G. O'Connell, D. Spring, 2009, Chemical record.

Synthesis of Structurally Diverse N‐Substituted Quaternary‐Carbon‐Containing Small Molecules from α,α‐Disubstituted Propargyl Amino Esters

Andreas Bender, David R Spring, Leen Kalash, 2018, Chemistry.

Diversity-oriented synthesis: producing chemical tools for dissecting biology.

David R Spring, D. Spring, Henning S. g. Beckmann, 2012, Chemical Society reviews.

Two-directional synthesis as a tool for diversity-oriented synthesis: Synthesis of alkaloid scaffolds

David R Spring, Kieron M. G. O'Connell, Warren R J D Galloway, 2012, Beilstein journal of organic chemistry.

Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform.

Stuart L Schreiber, David R Spring, Helen E Blackwell, 2002, Journal of the American Chemical Society.

Quorum sensing in Gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways.

James T Hodgkinson, David R Spring, Martin Welch, 2011, Chemical reviews.

Skeletal diversity construction via a branching synthetic strategy.

Suzanne Fergus, Andreas Bender, David R Spring, 2006, Chemical communications.

Anti-MRSA agent discovery using diversity-oriented synthesis.

Andreas Bender, David R Spring, Martin Welch, 2008, Angewandte Chemie.

Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium(ii) catalyst† †Dedicated to Professor Stuart L. Schreiber on the occasion of his 60th birthday. ‡ ‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc05313k Click here for additional

Stephen J. Walsh, David R Spring, Martin Welch, 2017, Chemical science.

Controlling the contents of microdroplets by exploiting the permeability of PDMS.

Santoshkumar N. Patil, James T Hodgkinson, David R Spring, 2011, Lab on a chip.

Diversity-oriented synthesis; a spectrum of approaches and results.

Andreas Bender, David R Spring, A. Bender, 2008, Organic & biomolecular chemistry.

Complete functionalisation of small and large diameter bromopolystyrene beads; applications for solid-supported reagents, scavengers and diversity-oriented synthesis.

David R Spring, D. Spring, M. Ladlow, 2004, Organic & biomolecular chemistry.

High content screening of diverse compound libraries identifies potent modulators of tubulin dynamics.

David R Spring, Ashok R Venkitaraman, Luca Laraia, 2014, ACS medicinal chemistry letters.

Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules.

David R Spring, Warren R J D Galloway, D. Spring, 2010, Nature communications.

Identification of an anti-MRSA dihydrofolate reductase inhibitor from a diversity-oriented synthesis.

David R Spring, Martin Welch, Warren R J D Galloway, 2008, Chemical communications.

Synthesis of unprecedented scaffold diversity.

David R Spring, Warren R J D Galloway, D. Spring, 2009, Angewandte Chemie.

Gemmacin B: bringing diversity back into focus.

David R Spring, Martin Welch, D. Spring, 2008, Organic & biomolecular chemistry.

Using Ligand-Mapping Simulations to Design a Ligand Selectively Targeting a Cryptic Surface Pocket of Polo-Like Kinase 1

Chris Abell, Robert B Best, David R Spring, 2012, Angewandte Chemie.

Chemical genetics to chemical genomics: small molecules offer big insights.

David R Spring, D. Spring, D. R. Spring, 2005, Chemical Society reviews.

A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling.

David R Spring, Yaw Sing Tan, Feilin Nie, 2013, Nature chemistry.

Diversity-oriented synthesis; a challenge for synthetic chemists.

David R Spring, D. Spring, D. R. Spring, 2003, Organic & biomolecular chemistry.

Exploiting domino enyne metathesis mechanisms for skeletal diversity generation.

David R Spring, D. Spring, Richard J Spandl, 2008, Chemical communications.