J. Krucinska

发表

MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates.

Amy C Anderson, A. Anderson, J. Aeschlimann, 2016, Cell chemical biology.

Toward Broad Spectrum DHFR inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin-Resistant Staphylococcus aureus

Marcel S. Frenkel, Graham T. Holt, B. Donald, 2019, bioRxiv.

Toward Broad Spectrum DHFR inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin-Resistant Staphylococcus aureus.

Marcel S. Frenkel, Graham T. Holt, B. Donald, 2019, ACS infectious diseases.

Structural and Biochemical Studies of Dihydrofolate Reductase from Streptococcus pyogenes as a Target for Antifolate Antibiotics

D. Wright, J. Krucinska, B. Hajian, 2018, bioRxiv.

Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents.

H. Erlandsen, Jana Korduláková, Carolyn Shoen, 2019, Cell chemical biology.

Nanostructures of APOBEC3G Support a Hierarchical Assembly Model of High Molecular Mass Ribonucleoprotein Particles from Dimeric Subunits*

J. Wedekind, R. Gillilan, HaroldC. Smith, 2006, Journal of Biological Chemistry.

Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate

Eric R. May, V. Robinson, H. Erlandsen, 2019, Scientific Reports.

Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.

A. Anderson, V. Robinson, H. Erlandsen, 2019, Biochemistry.

Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens

H. Erlandsen, D. Wright, Debjani Si, 2022, Communications Biology.

APOBEC-1 complementation factor (ACF) forms RNA-dependent multimers.

H. C. Smith, A. Kumar, C. A. Galloway, 2010, Biochemical and biophysical research communications.

Direct Raman measurement of an elevated base pKa in the active site of a small ribozyme in a precatalytic conformation.

J. Wedekind, R. Spitale, P. Carey, 2009, Journal of the American Chemical Society.

Identification of an imino group indispensable for cleavage by a small ribozyme.

J. Wedekind, R. Spitale, G. Cristalli, 2009, Journal of the American Chemical Society.

Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme.

J. Wedekind, C. MacElrevey, Jason D Salter, 2008, RNA.

Water in the active site of an all-RNA hairpin ribozyme and effects of Gua8 base variants on the geometry of phosphoryl transfer.

J. Wedekind, V. Grum-Tokars, J. Krucinska, 2006, Biochemistry.

Conformational heterogeneity at position U37 of an all-RNA hairpin ribozyme with implications for metal binding and the catalytic structure of the S-turn.

J. Wedekind, V. Grum-Tokars, J. Krucinska, 2005, Biochemistry.

A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization.

J. Wedekind, J. Krucinska, A. Torelli, 2007, RNA.

A posteriori design of crystal contacts to improve the X-ray diffraction properties of a small RNA enzyme

J. Wedekind, R. Spitale, C. MacElrevey, 2007, Acta crystallographica. Section D, Biological crystallography.

Structure of a class II preQ1 riboswitch reveals ligand recognition by a new fold

Mohammad Salim, J. Wedekind, Joseph E. Wedekind, 2013, Nature chemical biology.

Comparison of a PreQ1 Riboswitch Aptamer in Metabolite-bound and Free States with Implications for Gene Regulation*

J. Wedekind, V. Bandarian, J. Jenkins, 2011, The Journal of Biological Chemistry.

The Structural Basis for Recognition of the PreQ0 Metabolite by an Unusually Small Riboswitch Aptamer Domain*♦

Vahe Bandarian, Andrew T Torelli, J. Wedekind, 2009, Journal of Biological Chemistry.

Structural Characterization of Nitrosomonas europaea Cytochrome c‐552 Variants with Marked Differences in Electronic Structure

J. Wedekind, N. Andersen, G. Zoppellaro, 2013, Chembiochem : a European journal of chemical biology.

A transition-state interaction shifts nucleobase ionization toward neutrality to facilitate small ribozyme catalysis.

J. Wedekind, P. Carey, Yuanyuan Chen, 2012, Journal of the American Chemical Society.

A hydrodynamic analysis of APOBEC3G reveals a monomer-dimer-tetramer self-association that has implications for anti-HIV function.

J. Wedekind, HaroldC. Smith, J. Krucinska, 2009, Biochemistry.

Shared traits on the reaction coordinates of ribonuclease and an RNA enzyme.

J. Wedekind, R. Spitale, J. Krucinska, 2008, Biochemical and biophysical research communications.

Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis

A. Anderson, Carolyn Shoen, M. Cynamon, 2016, PloS one.

Crystallographic analysis of small ribozymes and riboswitches.

J. Wedekind, J. Jenkins, J. Krucinska, 2012, Methods in molecular biology.

A hydrodynamic analysis of APOBEC3G reveals a monomer-dimer-tetramer self-association that has implications for anti-HIV function.

J. Wedekind, HaroldC. Smith, J. Krucinska, 2009, Biochemistry.

A comparison of vanadate to a 2 9 –5 9 linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization

J. Wedekind, J. Krucinska, A. Torelli, 2022 .

Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core.

J. Wedekind, R. Spitale, G. Cristalli, 2009, Biochemistry.