Hanyong Chen

发表

PPMP, a novel tubulin-depolymerizing agent against esophageal cancer in patient-derived tumor xenografts

Weiya Ma, A. Bode, Z. Dong, 2016, Oncotarget.

APIO-EE-9 is a novel Aurora A and B antagonist that suppresses esophageal cancer growth in a PDX mouse model

A. Bode, Z. Dong, Kangdong Liu, 2017, Oncotarget.

RSK2 phosphorylates T-bet to attenuate colon cancer metastasis and growth

Weiya Ma, A. Bode, Z. Dong, 2017, Proceedings of the National Academy of Sciences.

RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation

Weiya Ma, A. Bode, Z. Dong, 2018, Oncogene.

Taxifolin Suppresses UV-Induced Skin Carcinogenesis by Targeting EGFR and PI3K

A. Bode, Z. Dong, R. Lubet, 2012, Cancer Prevention Research.

Acetylshikonin suppressed growth of colorectal tumour tissue and cells by inhibiting the intracellular kinase, T‐lymphokine‐activated killer cell‐originated protein kinase.

Z. Dong, J. K. Kundu, Kangdong Liu, 2020, British Journal of Pharmacology.

Novel dual inhibitor for targeting PIM1 and FGFR1 kinases inhibits colorectal cancer growth in vitro and patient-derived xenografts in vivo

Z. Dong, Kangdong Liu, Ran Zhao, 2022, Acta pharmaceutica Sinica. B.

JNK1 and 2 play a negative role in reprogramming to pluripotent stem cells by suppressing Klf4 activity.

Yong-Yeon Cho, A. Bode, Z. Dong, 2014, Stem cell research.

Inhibition of LTA4H by bestatin in human and mouse colorectal cancer

G. Wang, A. Bode, Z. Dong, 2019, EBioMedicine.

PKCι is a target of 7,8,4′‐trihydroxyisoflavone for the suppression of UVB‐induced MMP‐1 expression

A. Bode, Z. Dong, K. Lee, 2018, Experimental dermatology.

Src kinase is a direct target of apigenin against UVB-induced skin inflammation.

Z. Dong, K. Lee, H. Lee, 2013, Carcinogenesis.

Cirsiliol targets tyrosine kinase 2 to inhibit esophageal squamous cell carcinoma growth in vitro and in vivo

Z. Dong, Kangdong Liu, Wenna Nie, 2021, Journal of experimental & clinical cancer research : CR.

Coumestrol Epigenetically Suppresses Cancer Cell Proliferation: Coumestrol Is a Natural Haspin Kinase Inhibitor

Jong Hun Kim, Z. Dong, K. Lee, 2017, International journal of molecular sciences.

Targeting integrin αvβ3 with indomethacin inhibits patient‐derived xenograft tumour growth and recurrence in oesophageal squamous cell carcinoma

Z. Dong, Kangdong Liu, Xueli Tian, 2021, Clinical and translational medicine.

Anti‐arthritis effects of (E)‐2,4‐bis(p‐hydroxyphenyl)‐2‐butenal are mediated by inhibition of the STAT3 pathway

Tae Myoung Kim, Z. Dong, D. Kim, 2014, British journal of pharmacology.

Naproxen Induces Cell-Cycle Arrest and Apoptosis in Human Urinary Bladder Cancer Cell Lines and Chemically Induced Cancers by Targeting PI3K

A. Bode, Z. Dong, Mi-Sung Kim, 2013, Cancer Prevention Research.

7,3′,4′-Trihydroxyisoflavone, a Metabolite of the Soy Isoflavone Daidzein, Suppresses α-Melanocyte-Stimulating Hormone-Induced Melanogenesis by Targeting Melanocortin 1 Receptor

Z. Dong, J. Kim, N. Kang, 2020, Frontiers in Molecular Biosciences.

The Daidzein Metabolite, 6,7,4'-Trihydroxyisoflavone, Is a Novel Inhibitor of PKCα in Suppressing Solar UV-Induced Matrix Metalloproteinase 1

A. Bode, Z. Dong, Jong-Eun Kim, 2014, International journal of molecular sciences.

FGFR2 regulation by picrasidine Q inhibits the cell growth and induces apoptosis in esophageal squamous cell carcinoma

Z. Dong, Kangdong Liu, Mee‐Hyun Lee, 2018, Journal of cellular biochemistry.

overcomes gefitinib resistance in non-small cell lung cancer cells

Xiaoyu, A. Bode, Z. Dong, 2015 .

Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity.

A. Bode, Z. Dong, E. Cho, 2016, Cancer research.

Gossypin inhibits gastric cancer growth by direct targeting of AURKA and RSK2

A. Bode, Z. Dong, Kangdong Liu, 2018, Phytotherapy research : PTR.

GSK3β-Mediated Expression of CUG-Translated WT1 Is Critical for Tumor Progression

A. Bode, Z. Dong, K. Yao, 2020, Cancer Research.

Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo

A. Bode, Z. Dong, Yin Li, 2018, Molecular Cancer Therapeutics.

Aurora B kinase as a novel molecular target for inhibition the growth of osteosarcoma

A. Bode, Z. Dong, Kangdong Liu, 2019, Molecular carcinogenesis.

Curcumin Suppresses Proliferation of Colon Cancer Cells by Targeting CDK2

A. Bode, Z. Dong, Zunnan Huang, 2014, Cancer Prevention Research.

244-MPT overcomes gefitinib resistance in non-small cell lung cancer cells

A. Bode, Z. Dong, Kangdong Liu, 2015, Oncotarget.

6-C-(E-phenylethenyl)-naringenin suppresses colorectal cancer growth by inhibiting cyclooxygenase-1.

A. Bode, Z. Dong, F. Zhu, 2014, Cancer research.

Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis

Wei Li, Min Tang, Zigang Dong, 2015, Oncotarget.

ERK1 phosphorylates Nanog to regulate protein stability and stem cell self-renewal.

Yong-Yeon Cho, A. Bode, Z. Dong, 2014, Stem cell research.

ARC Is a Critical Protector against Inflammatory Bowel Disease (IBD) and IBD-Associated Colorectal Tumorigenesis

Weiya Ma, A. Bode, Z. Dong, 2020, Cancer Research.

TRAF1 Is Critical for Regulating the BRAF/MEK/ERK Pathway in Non-Small Cell Lung Carcinogenesis.

Weiya Ma, A. Bode, Z. Dong, 2018, Cancer research.

The Prolyl Isomerase Pin1 Is a Novel Target of 6,7,4′-Trihydroxyisoflavone for Suppressing Esophageal Cancer Growth

A. Bode, Z. Dong, Kangdong Liu, 2017, Cancer Prevention Research.

Discovery of a novel dual-target inhibitor against RSK1 and MSK2 to suppress growth of human colon cancer

Z. Dong, Kangdong Liu, K. Yao, 2020, Oncogene.

A Small Molecule Inhibitor of the β-Catenin-TCF4 Interaction Suppresses Colorectal Cancer Growth In Vitro and In Vivo

A. Bode, Z. Dong, Kangdong Liu, 2017, EBioMedicine.

Esculetin Suppresses Proliferation of Human Colon Cancer Cells by Directly Targeting β-Catenin

A. Bode, Z. Dong, Y. Surh, 2013, Cancer Prevention Research.

Ethyl gallate as a novel ERK1/2 inhibitor suppresses patient‐derived esophageal tumor growth

A. Bode, Z. Dong, Kangdong Liu, 2018, Molecular carcinogenesis.

Multifunctional effects of honokiol as an anti-inflammatory and anti-cancer drug in human oral squamous cancer cells and xenograft.

Z. Dong, J. Shim, Tae-Hoon Lee, 2015, Biomaterials.

Characterization of pomiferin triacetate as a novel mTOR and translation inhibitor.

K. Gustafson, Z. Dong, N. Colburn, 2014, Biochemical pharmacology.

3,6,2′,4′,5′-Pentahydroxyflavone, an Orally Bioavailable Multiple Protein Kinase Inhibitor, Overcomes Gefitinib Resistance in Non-small Cell Lung Cancer*

Weiya Ma, A. Bode, Z. Dong, 2014, The Journal of Biological Chemistry.

The Ashitaba (Angelica keiskei) Chalcones 4-hydroxyderricin and Xanthoangelol Suppress Melanomagenesis By Targeting BRAF and PI3K

S. Lippman, Weiya Ma, A. Bode, 2018, Cancer Prevention Research.

Butein, a novel dual inhibitor of MET and EGFR, overcomes gefitinib‐resistant lung cancer growth

A. Bode, Z. Dong, C. Jeong, 2015, Molecular carcinogenesis.

Isoliquiritigenin Induces Apoptosis and Inhibits Xenograft Tumor Growth of Human Lung Cancer Cells by Targeting Both Wild Type and L858R/T790M Mutant EGFR*

Yong-Yeon Cho, A. Bode, Z. Dong, 2014, The Journal of Biological Chemistry.

Dasatinib Inhibits Lung Cancer Cell Growth and Patient Derived Tumor Growth in Mice by Targeting LIMK1

Z. Dong, Kangdong Liu, Ran Zhao, 2020, Frontiers in Cell and Developmental Biology.

Computational and Biochemical Discovery of RSK2 as a Novel Target for Epigallocatechin Gallate (EGCG)

A. Bode, Z. Dong, K. Yao, 2015, PloS one.

Src is a novel potential off‐target of RXR agonists, 9‐cis‐UAB30 and Targretin, in human breast cancer cells

A. Bode, Z. Dong, Mi-Sung Kim, 2015, Molecular carcinogenesis.

SDCBP/MDA-9/syntenin phosphorylation by AURKA promotes esophageal squamous cell carcinoma progression through the EGFR-PI3K-Akt signaling pathway

Z. Dong, Kangdong Liu, Yaqiu Zheng, 2020, Oncogene.

Role of transcription factor Sp1 in the 4-O-methylhonokiol-mediated apoptotic effect on oral squamous cancer cells and xenograft.

Z. Dong, J. Shim, N. Choi, 2015, The international journal of biochemistry & cell biology.

ADA-07 Suppresses Solar Ultraviolet–Induced Skin Carcinogenesis by Directly Inhibiting TOPK

D. Alberts, Weiya Ma, A. Bode, 2017, Molecular Cancer Therapeutics.

Costunolide suppresses melanoma growth via the AKT/mTOR pathway in vitro and in vivo.

Z. Dong, Mee‐Hyun Lee, Z. Ryoo, 2021, American journal of cancer research.

Licochalcone A, a Natural Inhibitor of c-Jun N-Terminal Kinase 1

Weiya Ma, A. Bode, Z. Dong, 2013, Cancer Prevention Research.

HI-511 overcomes melanoma drug resistance via targeting AURKB and BRAF V600E

Weiya Ma, A. Bode, Z. Dong, 2020, Theranostics.

CDK12 and PAK2 as novel therapeutic targets for human gastric cancer

Z. Dong, Kangdong Liu, S. Shin, 2020, Theranostics.

Eupafolin suppresses prostate cancer by targeting phosphatidylinositol 3‐kinase‐mediated Akt signaling

A. Bode, Z. Dong, Kangdong Liu, 2015, Molecular carcinogenesis.

Scutellarin Suppresses Patient-Derived Xenograft Tumor Growth by Directly Targeting AKT in Esophageal Squamous Cell Carcinoma

A. Bode, Z. Dong, Kangdong Liu, 2019, Cancer Prevention Research.

Acetylshikonin suppressed growth of colorectal tumour tissue and cells by inhibiting the intracellular kinase, T‐lymphokine‐activated killer cell‐originated protein kinase.

Z. Dong, J. K. Kundu, Kangdong Liu, 2020, British journal of pharmacology.

Cell growth inhibition by 3-deoxysappanchalcone is mediated by directly targeting the TOPK signaling pathway in colon cancer.

A. Bode, Z. Dong, Ran Zhao, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

TOPK promotes metastasis of esophageal squamous cell carcinoma by activating the Src/GSK3β/STAT3 signaling pathway via γ-catenin

Kangdong Liu, Z. Dong, Yanan Jiang, 2019, BMC Cancer.

TOPK Promotes Metastasis of Esophageal Squamous Cell Carcinoma by Activating Src/GSK3β/STAT3 Signal Pathway though γ-catenin

Kangdong Liu, Yanan Jiang, Zi-min Dong, 2019 .

Crystal structure of the human PRPK–TPRKB complex

Weiya Ma, A. Bode, Z. Dong, 2021, Communications Biology.

Crystal structure of the human PRPK–TPRKB complex

Weiya Ma, A. Bode, Z. Dong, 2021, Communications biology.

Periplogenin suppresses the growth of esophageal squamous cell carcinoma in vitro and in vivo by targeting STAT3

Z. Dong, Jiuzhou Zhao, Kangdong Liu, 2021, Oncogene.

Targeted therapy of the AKT kinase inhibits esophageal squamous cell carcinoma growth in vitro and in vivo

A. Bode, Z. Dong, Kangdong Liu, 2019, International journal of cancer.

Herbacetin suppresses cutaneous squamous cell carcinoma and melanoma cell growth by targeting AKT and ODC

A. Bode, Z. Dong, Kangdong Liu, 2017, Carcinogenesis.

Prediction of Molecular Targets of Cancer Preventing Flavonoid Compounds Using Computational Methods

Zigang Dong, Ronald A. Lubet, Ann M. Bode, 2012, PloS one.

A Novel Cinnamon-Related Natural Product with Pim-1 Inhibitory Activity Inhibits Leukemia and Skin Cancer.

A. Bode, Z. Dong, K. Lee, 2015, Cancer research.

Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2

A. Bode, Z. Dong, Kangdong Liu, 2018, Oncotarget.

3,3'-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX1/2 and ERK1/2.

A. Bode, Z. Dong, Kangdong Liu, 2019, Cancer letters.

Caffeic Acid Directly Targets ERK1/2 to Attenuate Solar UV-Induced Skin Carcinogenesis

A. Bode, Z. Dong, Z. Dong, 2014, Cancer Prevention Research.

Gossypetin is a novel MKK3 and MKK6 inhibitor that suppresses esophageal cancer growth in vitro and in vivo.

A. Bode, Z. Dong, Kangdong Liu, 2019, Cancer letters.

Purpurogallin is a novel mitogen‐activated protein kinase kinase 1/2 inhibitor that suppresses esophageal squamous cell carcinoma growth in vitro and in vivo

A. Bode, Z. Dong, Kangdong Liu, 2019 .

The CUG-translated WT1, not AUG-WT1, is an oncogene

A. Bode, Z. Dong, S. Jung, 2017, Carcinogenesis.

Select Dietary Phytochemicals Function as Inhibitors of COX-1 but Not COX-2

A. Bode, Z. Dong, F. Zhu, 2013, PloS one.

Kaempferol Targets RSK2 and MSK1 to Suppress UV Radiation-Induced Skin Cancer

Weiya Ma, A. Bode, Z. Dong, 2014, Cancer Prevention Research.

Molecular Carcinogenesis