P. Pratheeshkumar

发表

Luteolin Inhibits Human Prostate Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2-Mediated Angiogenesis

Xianglin Shi, Zhuo Zhang, Jeong-Chae Lee, 2012, PloS one.

Ethanol enhances arsenic-induced cyclooxygenase-2 expression via both NFAT and NF-κB signalings in colorectal cancer cells.

Xianglin Shi, Zhuo Zhang, Jia Luo, 2015, Toxicology and applied pharmacology.

Reactive oxygen species mediate Cr(VI)-induced carcinogenesis through PI3K/AKT-dependent activation of GSK-3β/β-catenin signaling.

Xianglin Shi, Zhuo Zhang, Jeong-Chae Lee, 2013, Toxicology and applied pharmacology.

Downregulation of SKP2 in Papillary Thyroid Cancer Acts Synergistically With TRAIL on Inducing Apoptosis via ROS

K. Al-Kuraya, A. Siraj, S. Al-Sobhi, 2018, The Journal of clinical endocrinology and metabolism.

Vernolide-A inhibits tumour specific angiogenesis by regulating proinflammatory cytokines, VEGF, MMPs and TIMP.

G. Kuttan, P. Pratheeshkumar, G. Kuttan,, 2011, European journal of pharmacology.

Protective role of perillic acid against radiation-induced oxidative stress, cytokine profile, DNA damage, and intestinal toxicity in mice.

G. Kuttan, T. J. Raphael, P. Pratheeshkumar, 2010, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.

PD-L1 Is an Independent Prognostic Marker in Middle Eastern PTC and Its Expression Is Upregulated by BRAFV600E Mutation

K. Al-Kuraya, A. Siraj, S. Al-Sobhi, 2021, Cancers.

XIAP over-expression is an independent poor prognostic marker in Middle Eastern breast cancer and can be targeted to induce efficient apoptosis

K. Al-Kuraya, A. Siraj, Maqbool Ahmed, 2017, BMC Cancer.

Cancer Stem-Like Cells Accumulated in Nickel-Induced Malignant Transformation.

Xianglin Shi, Zhuo Zhang, Young-Ok Son, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Quercetin Inhibits Angiogenesis Mediated Human Prostate Tumor Growth by Targeting VEGFR- 2 Regulated AKT/mTOR/P70S6K Signaling Pathways

Xianglin Shi, Zhuo Zhang, Jeong-Chae Lee, 2012, PloS one.

Protective role of Vernonia cinerea L. against gamma radiation—induced immunosupression and oxidative stress in mice

G. Kuttan, P. Pratheeshkumar, G. Kuttan,, 2011, Human & experimental toxicology.

Cardiospermum halicacabum inhibits cyclophosphamide induced immunosupression and oxidative stress in mice and also regulates iNOS and COX-2 gene expression in LPS stimulated macrophages.

G. Kuttan, P. Pratheeshkumar, G. Kuttan,, 2010, Asian Pacific journal of cancer prevention : APJCP.

Prognostic Value and Function of KLF5 in Papillary Thyroid Cancer

K. Al-Kuraya, S. Al-Sobhi, F. Al-Dayel, 2021, Cancers.

Induction of miR-21-PDCD4 signaling by UVB in JB6 cells involves ROS-mediated MAPK pathways.

Xianglin Shi, M. Ding, L. Bowman, 2013, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Vernolide-A inhibits radiation-induced hypoxia-mediated tumor angiogenesis by regulating HIF-1α, MMP-2, MMP-9, and VEGF.

G. Kuttan, P. Pratheeshkumar, G. Kuttan,, 2011, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.

Overexpression of PARP is an independent prognostic marker for poor survival in Middle Eastern breast cancer and its inhibition can be enhanced with embelin co-treatment

K. Al-Kuraya, F. Al-Dayel, D. Ajarim, 2018, Oncotarget.

Anti-apoptotic proteins and catalase-dependent apoptosis resistance in nickel chloride-transformed human lung epithelial cells

Shuang-yin Han, A. Budhraja, Lijuan Sun, 2013, International journal of oncology.

Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cells.

Xianglin Shi, Zhuo Zhang, J. A. Hitron, 2016, Toxicology and applied pharmacology.

Effect of vernolide-A, a sesquiterpene lactone from Vernonia cinerea L., on cell-mediated immune response in B16F-10 metastatic melanoma-bearing mice

G. Kuttan, P. Pratheeshkumar, G. Kuttan,, 2011, Immunopharmacology and immunotoxicology.

Epithelial-mesenchymal transition during oncogenic transformation induced by hexavalent chromium involves reactive oxygen species-dependent mechanism in lung epithelial cells.

Shuang-yin Han, A. Budhraja, Xin Wang, 2013, Toxicology and applied pharmacology.

Modulation of immune response by Vernonia cinerea L. inhibits the proinflammatory cytokine profile, iNOS, and COX-2 expression in LPS-stimulated macrophages

G. Kuttan, P. Pratheeshkumar, 2011, Immunopharmacology and immunotoxicology.

Oxidative stress and metal carcinogenesis.

Xianglin Shi, Jeong-Chae Lee, Young-Ok Son, 2012, Free radical biology & medicine.

Roles of ROS, Nrf2, and autophagy in cadmium‐carcinogenesis and its prevention by sulforaphane

Zhimin Chen, Xianglin Shi, Zhuo Zhang, 2018, Toxicology and applied pharmacology.

Nomilin Inhibits Metastasis via Induction of Apoptosis and Regulates the Activation of Transcription Factors and the Cytokine Profile in B16F-10 Cells

G. Kuttan, T. J. Raphael, P. Pratheeshkumar, 2012, Integrative cancer therapies.

Nomilin inhibits tumor-specific angiogenesis by downregulating VEGF, NO and proinflammatory cytokine profile and also by inhibiting the activation of MMP-2 and MMP-9.

G. Kuttan, P. Pratheeshkumar, 2011, European journal of pharmacology.

Quercitrin protects skin from UVB-induced oxidative damage.

Xianglin Shi, Zhuo Zhang, N. Gao, 2013, Toxicology and applied pharmacology.

Vernonia cinerea Less. Inhibits Tumor Cell Invasion and Pulmonary Metastasis in C57BL/6 Mice

G. Kuttan, P. Pratheeshkumar, G. Kuttan,, 2011, Integrative cancer therapies.

Ameliorative action of Vernonia cinerea L. on cyclophosphamide-induced immunosuppression and oxidative stress in mice

G. Kuttan, P. Pratheeshkumar, G. Kuttan,, 2010, Inflammopharmacology.

Cancer prevention with promising natural products: mechanisms of action and molecular targets.

Xianglin Shi, Zhuo Zhang, Jeong-Chae Lee, 2012, Anti-cancer agents in medicinal chemistry.

Oleanolic acid induces apoptosis by modulating p53, Bax, Bcl-2 and caspase-3 gene expression and regulates the activation of transcription factors and cytokine profile in B16F.

G. Kuttan, P. Pratheeshkumar, 2011, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.

Diallyl disulfide induces caspase-dependent apoptosis via mitochondria-mediated intrinsic pathway in B16F-10 melanoma cells by up-regulating p53, caspase-3 and down-regulating pro-inflammatory cytokines and nuclear factor-κβ-mediated Bcl-2 activation.

P. Thejass, P. Pratheeshkumar, Girija Kutan, 2010, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.

Andrographolide induces apoptosis in B16F-10 melanoma cells by inhibiting NF-κB-mediated bcl-2 activation and modulating p53-induced caspase-3 gene expression

G. Kuttan, K. Sheeja, P. Pratheeshkumar, 2012, Immunopharmacology and immunotoxicology.

CHD4 Predicts Aggressiveness in PTC Patients and Promotes Cancer Stemness and EMT in PTC Cells

K. Al-Kuraya, S. Al-Sobhi, F. Al-Dayel, 2021, International journal of molecular sciences.

Epigenetic targets of arsenic: emphasis on epigenetic modifications during carcinogenesis.

Xianglin Shi, Zhuo Zhang, Young-Ok Son, 2015, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.

Blackberry extract inhibits UVB-induced oxidative damage and inflammation through MAP kinases and NF-κB signaling pathways in SKH-1 mice skin.

Xianglin Shi, Zhuo Zhang, Xin Wang, 2015, Toxicology and applied pharmacology.

Cyanidin-3-glucoside inhibits UVB-induced oxidative damage and inflammation by regulating MAP kinase and NF-κB signaling pathways in SKH-1 hairless mice skin.

Xianglin Shi, Zhuo Zhang, Xin Wang, 2014, Toxicology and applied pharmacology.

Retraction Note: Oncogenic transformation of human lung bronchial epithelial cells induced by arsenic involves ROS-dependent activation of STAT3-miR-21-PDCD4 mechanism

Xianglin Shi, Zhuo Zhang, Young-Ok Son, 2016, Scientific Reports.

Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling

Xianglin Shi, Zhuo Zhang, Young-Ok Son, 2016, Oncotarget.

Role of reactive oxygen species in arsenic-induced transformation of human lung bronchial epithelial (BEAS-2B) cells.

Xianglin Shi, Zhuo Zhang, A. Budhraja, 2015, Biochemical and biophysical research communications.

Modulation of cytotoxic T lymphocyte, natural killer cell, antibody-dependent cellular cytotoxicity, and antibody-dependent complement-mediated cytotoxicity by Vernonia cinerea L. and vernolide-A in BALB/c mice via enhanced production of cytokines IL-2 and IFN-γ

G. Kuttan, P. Pratheeshkumar, G. Kuttan,, 2012, Immunopharmacology and immunotoxicology.

Prognostic significance of DNMT3A alterations in Middle Eastern papillary thyroid carcinoma.

Tariq Ahmad Masoodi, K. Al-Kuraya, M. Al-Rasheed, 2019, European journal of cancer.

Environmental Disease 11-6-2015 Antioncogenic and Oncogenic Properties of Nrf 2 in Arsenic-Induced Carcinogenesis

Xianglin Shi, Zhuo Zhang, Jia Luo, 2019 .

Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells

Xianglin Shi, Zhuo Zhang, Young-Ok Son, 2017, The Journal of Biological Chemistry.

Quercetin inhibits Cr(VI)-induced malignant cell transformation by targeting miR-21-PDCD4 signaling pathway

Xianglin Shi, Zhuo Zhang, Young-Ok Son, 2016, Oncotarget.

TGFβ-induced SMAD4-dependent Apoptosis Proceeded by EMT in CRC

Tariq Ahmad Masoodi, K. Al-Kuraya, R. Bu, 2019, Molecular Cancer Therapeutics.

Constitutive Activation of Epidermal Growth Factor Receptor Promotes Tumorigenesis of Cr(VI)-transformed Cells through Decreased Reactive Oxygen Species and Apoptosis Resistance Development*

Xianglin Shi, K. Kondo, Zhuo Zhang, 2014, The Journal of Biological Chemistry.

Phytochemicals in Cancer Prevention and Therapy

Young-Ok Son, K. Siveen, P. Korangath, 2015, BioMed research international.

Antimetastatic potential of vernolide-A, a sesquiterpenoid from Vernonia cinerea L.

G. Kuttan, P. Pratheeshkumar, G. Kuttan,, 2012, Human & experimental toxicology.

Luteolin inhibits Cr(VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways.

Yitao Wang, Xianglin Shi, Zhuo Zhang, 2014, Toxicology and applied pharmacology.

Andrographolide inhibits human umbilical vein endothelial cell invasion and migration by regulating MMP-2 and MMP-9 during angiogenesis.

G. Kuttan, P. Pratheeshkumar, G. Kuttan,, 2011, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.

Apigenin suppresses migration and invasion of transformed cells through down-regulation of C-X-C chemokine receptor 4 expression.

Xianglin Shi, Zhuo Zhang, Jeong-Chae Lee, 2013, Toxicology and applied pharmacology.

Vernolide-A, a sesquiterpene lactone from Vernonia cinerea, induces apoptosis in B16F-10 melanoma cells by modulating p53 and caspase-3 gene expressions and regulating NF-κB-mediated bcl-2 activation

G. Kuttan, P. Pratheeshkumar, G. Kuttan,, 2011, Drug and chemical toxicology.

Inhibition of tumor progression by naturally occurring terpenoids

G. Kuttan, R. Kuttan, P. Pratheeshkumar, 2011, Pharmaceutical biology.

Krupple-Like Factor 5 is a Potential Therapeutic Target and Prognostic Marker in Epithelial Ovarian Cancer

K. Al-Kuraya, F. Al-Dayel, P. Pratheeshkumar, 2020, Frontiers in Pharmacology.

Arsenic Induces Insulin Resistance in Mouse Adipocytes and Myotubes Via Oxidative Stress-Regulated Mitochondrial Sirt3-FOXO3a Signaling Pathway.

Zhuo Zhang, Jia Luo, Young-Ok Son, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

XIAP over-expression is an independent poor prognostic marker in Middle Eastern breast cancer and can be targeted to induce efficient apoptosis

K. Al-Kuraya, Maqbool Ahmed, R. Bu, 2017, BMC Cancer.

Nrf2/p62 Signaling in Apoptosis Resistance and Its Role in Cadmium-induced Carcinogenesis*

Xianglin Shi, Zhuo Zhang, Young-Ok Son, 2014, The Journal of Biological Chemistry.

FoxM1 is an independent poor prognostic marker and therapeutic target for advanced Middle Eastern breast cancer

K. Al-Kuraya, F. Al-Dayel, Z. Qadri, 2018, Oncotarget.

Oncogenic transformation of human lung bronchial epithelial cells induced by arsenic involves ROS-dependent activation of STAT3-miR-21-PDCD4 mechanism

Xianglin Shi, Zhuo Zhang, Young-Ok Son, 2016, Scientific Reports.

FoxM1 and β-catenin predicts aggressiveness in Middle Eastern ovarian cancer and their co-targeting impairs the growth of ovarian cancer cells

K. Al-Kuraya, F. Al-Dayel, Norah M. Alhoshani, 2017, Oncotarget.

Activation of Epidermal Growth Factor Receptor/p38/Hypoxia-inducible Factor-1α Is Pivotal for Angiogenesis and Tumorigenesis of Malignantly Transformed Cells Induced by Hexavalent Chromium*

Xianglin Shi, K. Kondo, Zhuo Zhang, 2016, The Journal of Biological Chemistry.

Antioncogenic and Oncogenic Properties of Nrf2 in Arsenic-induced Carcinogenesis*

Xianglin Shi, Zhuo Zhang, Jia Luo, 2015, The Journal of Biological Chemistry.

Protection from Cr(VI)‐induced malignant cell transformation and tumorigenesis of Cr(VI)‐transformed cells by luteolin through Nrf2 signaling

Xianglin Shi, Zhuo Zhang, Young-Ok Son, 2017, Toxicology and applied pharmacology.

Withdrawal: Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells.

Xianglin Shi, Zhuo Zhang, Young-Ok Son, 2018, The Journal of Biological Chemistry.

Epithelial-mesenchymal transition during oncogenic transformation induced by hexavalent chromium involves reactive oxygen species-dependent mechanism in lung epithelial cells.

Shuang-yin Han, A. Budhraja, Xin Wang, 2013, Toxicology and applied pharmacology.

Nomilin inhibits tumor-specific angiogenesis by downregulating VEGF, NO and proinflammatory cytokine profile and also by inhibiting the activation of MMP-2 and MMP-9.

P. Pratheeshkumar, G. Kuttan,, 2011, European journal of pharmacology.