S. Giorgi-Renault

发表

Design, Synthesis, and Biological Evaluation of the First Podophyllotoxin Analogues as Potential Vascular‐Disrupting Agents

M. Vidal, C. Lenoir, C. Garbay, 2010, ChemMedChem.

Porphyrin-netropsin: A potential ligand of DNA

N. Gresh, M. Perrée-fauvet, P. Helissey, 1993 .

Binding of Net-Fla, a netropsin-flavin hybrid molecule, to DNA: molecular mechanics and dynamics studies in vacuo and in water solution.

M. Bouziane, M. Le Bret, C. Auclair, 1996, Journal of biomolecular structure & dynamics.

A FACILE ROUTE FOR THE PREPARATION OF N-PHENYL TETRAHYDROQUINOLINES AND TETRAHYDROISOQUINOLINES

C. Tratrat, P. Helissey, S. Giorgi-Renault, 2001 .

Polycyclic nitrogen heterocycles as potential thymidine phosphorylase inhibitors: synthesis, biological evaluation, and molecular docking study

M. Sari, P. Chavatte, A. Farce, 2021, Journal of enzyme inhibition and medicinal chemistry.

Poly(pyrrolecarboxamides) linked to photoactivable chromophore isoalloxazine. Synthesis, selective binding, and DNA cleaving properties.

C. Auclair, P. Helissey, S. Giorgi-Renault, 1994, Bioconjugate chemistry.

Inhibition of eukaryotic DNA topoisomerase I and II activities by indoloquinolinedione derivatives.

J. Riou, P. Helissey, S. Giorgi-Renault, 1991, Molecular pharmacology.

NEW SYNTHESIS OF 5,10-DIOXYPHENAZINE-2-CARBOXYLIC ACID

P. Helissey, S. Giorgi-Renault, M. Haroun, 2001 .

Heterocyclic quinones. 17. A new in vivo active antineoplastic drug: 6,7-bis(1-aziridinyl)-4-[[3-(N,N-dimethylamino)propyl]amino]-5,8- quinazolinedione.

C. Paoletti, F. Lavelle, S. Giorgi-Renault, 1991, Journal of medicinal chemistry.

A new synthetic approach to functionalize pyrimido[4,5-b]quinoline-2,4(1H,3H)-diones via a three-component one-pot reaction

P. Helissey, Stéphanie Desbène-Finck, S. Giorgi-Renault, 2010, Molecular Diversity.

Design and effective synthesis of the first 4-aza-2,3-didehydropodophyllotoxin rigid aminologue: a N-methyl-4-[(3,4,5-trimethoxyphenyl)amino)]-1,2-dihydroquinoline-lactone.

P. Helissey, Raphaël Labruère, Stéphanie Desbène-Finck, 2008, The Journal of organic chemistry.

A multicomponent reaction for the one-pot synthesis of 4-aza-2,3-didehydropodophyllotoxin and derivatives.

C. Tratrat, S. Giorgi-Renault, H. Husson, 2002, Organic letters.

Silver-Catalyzed Domino Hydroarylation/Cycloisomerization Reactions of 2-Alkynylquinoline-3-carbaldehydes: Access to (Hetero)arylpyranoquinolines

V. Michelet, P. Helissey, Stéphanie Desbène-Finck, 2016 .

Synthesis, antitumor evaluation and SAR of new 1H-pyrrolo [3,2-c] quinoline-6,9-diones and 11H-indolo [3,2-c] quinoline-1,4-diones.

P. Helissey, S. Giorgi-Renault, S. Cros, 1994, Anti-cancer drug design.

A Convenient Route to Quinolone‐Fused Imides and Lactams: Synthesis of Pyrrolo[3,4‐b]quinoline‐3,9‐diones and 1,3,9‐Triones by Oxidation of Indole Derivatives.

C. Tratrat, S. Giorgi-Renault, H. Husson, 1999 .

A Convenient Route to Quinolone-Fused Imides and Lactams: Synthesis of Pyrrolo[3,4-b]quinoline-3,9-diones and 1,3,9-triones by Oxidation of Indole Derivatives

C. Tratrat, S. Giorgi-Renault, H. Husson, 1998 .

Heterocyclic quinones. XIV. Pharmacomodulation in a series of 11H-indolo[3,2-c]quinolinediones: synthesis and cytotoxicity of 8-substituted 11H-indolo[3,2-c]quinoline-7,10-diones.

P. Helissey, S. Giorgi-Renault, S. Cros, 1989, Chemical & pharmaceutical bulletin.

Structure-mutagenicity relationships in a series of indolo[3,2-c]quinoline-1,4-diones that have shown cytotoxic properties on leukemia cells.

B. Festy, P. Helissey, S. Giorgi-Renault, 1992, Mutation research.

Drugs that inhibit tubulin polymerization: the particular case of podophyllotoxin and analogues.

S. Giorgi-Renault, S. Desbene, S. Desbène, 2012, Current medicinal chemistry. Anti-cancer agents.

New Synthesis of 5,10‐Dioxyphenazine‐2‐carboxylic Acid.

P. Helissey, S. Giorgi-Renault, M. Haroun, 2001 .

Sequence-recognition and cleavage of DNA by a netropsin-phenazine-di-N-oxide conjugate.

C. Bailly, P. Colson, C. Houssier, 2000, Bioconjugate chemistry.

Synthesis of New Furo[3,4‐b]quinolin‐1(3H)‐one Scaffolds Derived from γ‐Lactone‐Fused Quinolin‐4(1H)‐ones

P. Helissey, Raphaël Labruère, Stéphanie Desbène-Finck, 2013 .

Phase Transfer Catalysis: A Convenient Synthesis of O,O-Diethyl O-(4-Quinolinyl) Phosphorothioates

S. Giorgi-Renault, J. Renault, Z. Bukovec, 1984 .

In vitro inhibition of the pim-1 protooncogene by chimeric oligodeoxyribonucleotides composed of a- and β-anomeric fragments

F. Dautry, C. Malvy, J. Bertrand, 1994 .

Alpha beta chimeric antisense oligonucleotides: synthesis and nuclease resistance in biological media.

C. Malvy, J. Bertrand, E. Lescot, 1994, Antisense research and development.

α−β Chimeric Oligonucleotides Form a New Stable “Snail-like” Structure

O. Fedorova, C. Malvy, J. Bertrand, 1996 .

Easy Access to 1H-Pyrrolo[3′,4′:5,6]pyrido[2,3-d]pyrimidine-2,4,6,8(3H,7H)-tetraone and Selectively N7-Substituted Analogues through Key Synthons

Éric Merlet, P. Helissey, Stéphanie Desbène-Finck, 2015 .

Easy Access to 1H-Pyrrolo[3′,4′:5,6]pyrido[2,3-d]pyrimidine-2,4,6,8(3H,7H)-tetraone and Selectively N7-Substituted Analogues Through Key Synthons.

Éric Merlet, P. Helissey, Stéphanie Desbène-Finck, 2016 .

Synthesis of γ-and δ-lactones derived from 4-quinolone-3-carboxylic acid

C. Guillou, J. Quirion, S. Giorgi-Renault, 1997 .

Structure-mutagenicity relationships in series of 11H-indolo[3,2-c]quinoline-1,4-diones, tetrahydro-11H-indolo[3,2-c]quinoline-1,4-diones and 11H-pyrido[3',4':4,5]pyrrolo[3,2-c]quinoline-1,4-diones with leukemia cytotoxic properties. Relations with topoisomerase I inhibiting properties.

B. Festy, P. Helissey, S. Giorgi-Renault, 1994, Mutation research.

Alkylation of 5‐ and 6‐Methylindolo[2,3‐b]quinoxalines: Revised Structures of the N,N′‐Dimethylated Salts

P. Helissey, Stéphanie Desbène-Finck, S. Giorgi-Renault, 2005 .

2,3-bis(2-pyridyl)-5,8-quinoxalinediones with metal chelating properties: synthesis and biological evaluation.

J. Hénichart, P. Helissey, J. Bernier, 1989, Journal of pharmaceutical sciences.

Structure-activity relationships of a series of antitumoral 5,8-quinazolinediones in mutagenicity studies.

B. Festy, S. Giorgi-Renault, F. Callais, 1991, Mutation research.

Heterocyclic quinones. XVI. Pharmacomodulation in the series of 11H-indolo[3,2-c]quinolinediones: synthesis, cytotoxicity and antitumor activity of 3-substituted 11H-pyrido[3',4':4,5]pyrrolo[3,2-c]quinoline-1,4-diones.

P. Helissey, S. Giorgi-Renault, S. Cros, 1989, Chemical & pharmaceutical bulletin.

Design of a Composite Ethidium–Netropsin–Anilinoacridine Molecule for DNA Recognition

Christian Bailly, Michelyne Haroun, C. Bailly, 2003, Chembiochem : a European journal of chemical biology.

Synthesis and reactivity of a N-aryl-2-vinyltetrahydro-4-oxoquinoline

C. Guillou, J. Quirion, S. Giorgi-Renault, 1998 .

Heterocyclic Quinones. 4. A new highly cytotoxic drug: 6,7-bis(1-aziridinyl)-5,8-quinazolinedione.

C. Paoletti, P. Mailliet, S. Giorgi-Renault, 1983, Journal of medicinal chemistry.