Lamees Hegazy

发表

Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold.

Subhashish Banerjee, Mohamed Elagawany, T. Burris, 2019, Bioorganic & medicinal chemistry letters.

The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids.

Ian Mitchelle S. de Vera, T. Burris, Thomas Koelblen, 2020, Cell chemical biology.

Synthesis and structure activity relationship of the first class of LXR inverse agonists

T. Kamenecka, T. Burris, Paolo Di Fruscia, 2022, Bioorganic Chemistry.

Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor.

Yuanying Fang, B. Finck, Bahaa Elgendy, 2021, Journal of medicinal chemistry.

Identification of 4-isopropyl–thiotropolone as a novel anti-microbial: regioselective synthesis, NMR characterization, and biological evaluation

J. Tavis, M. Donlin, Mohamed Elagawany, 2018, RSC advances.

Catalyst- and organic solvent-free synthesis of thioacids in water

Mohamed Elagawany, Bahaa Elgendy, Lamees Hegazy, 2019, Tetrahedron Letters.

A Synthetic ERRα Agonist Induces an Acute Aerobic Exercise Response and Enhances Exercise Capacity

M. Downes, J. Huss, J. Chrivia, 2022, bioRxiv.

Synthesis, Anti‐Breast Cancer Activity, and Molecular Modeling of Some Benzothiazole and Benzoxazole Derivatives

M. Rateb, M. Abdelgawad, A. Belal, 2013, Archiv der Pharmazie.

A sulfoximine-based inhibitor of human asparagine synthetase kills L-asparaginase-resistant leukemia cells.

N. Richards, J. Hiratake, B. Watanabe, 2012, Bioorganic & medicinal chemistry.

Modulation of estrogen-related receptors subtype selectivity: Conversion of an ERRβ/γ selective agonist to ERRα/β/γ pan agonists.

Mohamed Elagawany, T. Burris, M. Shahien, 2020, Bioorganic chemistry.

Synthesis and DFT studies of an antitumor active spiro-oxindole

Riham F. George, ElSayed M Shalaby, A. S. Girgis, 2015 .

Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB

T. Burris, John K Walker, Thomas Koelblen, 2022, Nature Communications.

Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice

Kevin Cho, G. Patti, M. Ilagan, 2021, The Journal of biological chemistry.

Identification of Novel Mitochondrial Pyruvate Carrier Inhibitors by Homology Modeling and Pharmacophore-Based Virtual Screening

B. Finck, K. McCommis, Bahaa Elgendy, 2022, Biomedicines.

The larvicidal activity of natural inspired piperine-based dienehydrazides against Culex pipiens.

Manqun Wang, Ahmed H. Tantawy, Lamees Hegazy, 2019, Bioorganic chemistry.

Catalyst-and organic solvent-free synthesis, structural, and theoretical studies of 1-arylidenamino-2,4-disubstituted-2-imidazoline-5-ones

Mohamed Elagawany, A. Amin, N. Rath, 2020 .

Recent Advances in the Medicinal Chemistry of Liver X Receptors.

T. Burris, Lamees Hegazy, M. Arief, 2018, Journal of medicinal chemistry.

Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity.

M. Downes, J. Huss, J. Chrivia, 2023, ACS chemical biology.

Distinct REV-ERBα Conformational State Predicted by GaMD Simulations Leads to the Structure-Based Discovery of Novel REV-ERBα Antagonist

T. Burris, Bahaa Elgendy, Lamees Hegazy, 2021, bioRxiv.

Optimized CGenFF force-field parameters for acylphosphate and N-phosphonosulfonimidoyl functional groups

N. Richards, Lamees Hegazy, 2013, Journal of Molecular Modeling.

A sulfoximine-based inhibitor of human asparagine synthetase kills L-asparaginase-resistant leukemia cells.

N. Richards, J. Hiratake, Takuya Otokawa, 2012, Bioorganic & medicinal chemistry.

Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor

Timothy W. Craven, D. Craik, Roland Hellinger, 2023, Nature communications.