C. Shih

发表

Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastomas

R. Weinberg, D. Cowing, L. Padhy, 1982, Cell.

Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model

Chun-Che Liao, Chih-Shin Chang, C. Shih, 2019, Journal of Biomedical Science.

Progress in Cloning the Transforming Gene from Chemically-Transformed Mouse Cells

R. Weinberg, B. Shilo, L. Padhy, 1980 .

Three different human tumor cell lines contain different oncogenes

R. Weinberg, B. Shilo, M. Murray, 1981, Cell.

A Polysaccharide Purified From Ganoderma lucidum Acts as a Potent Mucosal Adjuvant That Promotes Protective Immunity Against the Lethal Challenge With Enterovirus A71

B. Chiang, C. Shih, Yu‐Li Lin, 2020, Frontiers in Immunology.

Cell surface heparan sulfates mediate internalization of the PWWP/HATH domain of HDGF via macropinocytosis to fine-tune cell signalling processes involved in fibroblast cell migration.

Tai-Huang Huang, S. Sue, Shao‐Chen Lee, 2011, The Biochemical journal.

Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts

R. Weinberg, M. Murray, L. Padhy, 1981, Nature.

Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

R. Weinberg, C. Tabin, L. Parada, 1982, Nature.

Hepatocyte-Like Cells Transdifferentiated from a Pancreatic Origin Can Support Replication of Hepatitis B Virus

D. Tosh, Robert Y. L. Wang, Chia-Ning Shen, 2005, Journal of Virology.

Hepatitis B Virus.

C. Shih, An-Ting Liou, Ching-Chun Yang, 2018, Trends in microbiology.

Use of RNA interference to modulate liver adenoma development in a murine model transgenic for hepatitis B virus

M. Gershwin, M. Tao, K. Jeng, 2011, Gene Therapy.

1-Hydroxy-3-[(E)-4-(piperazine-diium)but-2-enyloxy]-9,10-anthraquinone ditrifluoroactate induced autophagic cell death in human PC3 cells.

C. Su, H. Hsu, A. Huang, 2018, Chemico-biological interactions.

Nuclear Export of Human Hepatitis B Virus Core Protein and Pregenomic RNA Depends on the Cellular NXF1-p15 Machinery

P. Su, E. Huang, C. Shih, 2014, PloS one.

Enterovirus 71 targets the cardiopulmonary system in a robust oral infection mouse model

Ya-Ting Chang, Chien-Chang Chen, Chun-Che Liao, 2019, Scientific Reports.

Identification of a Novel Antimicrobial Peptide from Human Hepatitis B Virus Core Protein Arginine-Rich Domain (ARD)

P. Su, Hui‐Ming Yu, Y. Liao, 2013, PLoS pathogens.

Adding a C-terminal Cysteine (CTC) Can Enhance the Bactericidal Activity of Three Different Antimicrobial Peptides

S. Kuo, P. Su, T. Lauderdale, 2018, Front. Microbiol..

Hepatitis B virus virion secretion is a CRM1-spike-mediated late event

P. Su, Wen-chang Lin, C. Shih, 2022, Journal of biomedical science.

MicroRNA miR-204 and miR-1236 inhibit hepatitis B virus replication via two different mechanisms

Jyun-Yuan Huang, Hung-Lin Chen, C. Shih, 2016, Scientific Reports.

ATTEMPTS AT THE MOLECULAR CLONING OF A TRANSFORMING ALLELE FROM CHEMICALLY TRANSFORMED MOUSE CELLS

R. Weinberg, B. Shilo, L. Padhy, 1980 .

Replication Advantage and Host Factor-Independent Phenotypes Attributable to a Common Naturally Occurring Capsid Mutation (I97L) in Human Hepatitis B Virus

F. Suk, C. Shih, Sheng-Hsuan Chen, 2002, Journal of Virology.

Immunocompetent and Immunodeficient Mouse Models for Enterovirus 71 Pathogenesis and Therapy

Chun-Che Liao, Chih-Shin Chang, C. Shih, 2018, Viruses.

INITIATION OF MOLECULAR CLONING OF A TRANSFORMING ALLELE OF CHEMICALLY TRANSFORMED MOUSE CELLS1

R. Weinberg, B. Shilo, M. Goldfarb, 1980 .

In vitro propagation of human hepatitis B virus in a rat hepatoma cell line.

C. Shih, M. Ho, S. Roychoudhury, 1989, Proceedings of the National Academy of Sciences of the United States of America.

A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71

Chun-Che Liao, Chih-Shin Chang, C. Shih, 2016, Scientific Reports.

Reduced Secretion of Virions and Hepatitis B Virus (HBV) Surface Antigen of a Naturally Occurring HBV Variant Correlates with the Accumulation of the Small S Envelope Protein in the Endoplasmic Reticulum and Golgi Apparatus

Robert Y. L. Wang, F. Suk, C. Shih, 2005, Journal of Virology.

Detection of hypermodified middle-envelope (M) proteins secreted from naturally occurring HBV variants containing a preS2 internal deletion.

C. Shih, P. Tai, 2004, Methods in molecular medicine.

Hypermodification and immune escape of an internally deleted middle-envelope (M) protein of frequent and predominant hepatitis B virus variants.

W. Gerlich, A. Neurath, F. Suk, 2002, Virology.

Core antigen mutations of human hepatitis B virus in hepatomas accumulate in MHC class II-restricted T cell epitopes.

C. S. Lee, C. Yang, W. Wang, 1995, Virology.

The Mechanism of an Immature Secretion Phenotype of a Highly Frequent Naturally Occurring Missense Mutation at Codon 97 of Human Hepatitis B Virus Core Antigen

C. Shih, G. K. Sahu, W. Whitehead, 1999, Journal of Virology.

Pregenomic RNA encapsidation analysis of eleven missense and nonsense polymerase mutants of human hepatitis B virus

A. Faruqi, C. Shih, S. Roychoudhury, 1991, Journal of virology.

Novel Naturally Occurring Mutations of Enterovirus 71 Associated With Disease Severity

M. Hwang, Chun-Che Liao, Chih-Shin Chang, 2021, Frontiers in Microbiology.

Heparin at physiological concentration can enhance PEG-free in vitro infection with human hepatitis B virus

Hwai I. Yang, Ming‐Lung Yu, W. Chuang, 2017, Scientific Reports.

core assembled from full-length core protein.

Xuekui Yu, J. Jih, C. Shih, 2013 .

Improvement of in vivo antimicrobial activity of HBcARD peptides by D-arginine replacement

P. Su, C. Shih, Heng-Li Chen, 2016, Applied Microbiology and Biotechnology.

Stability and Morphology Comparisons of Self-AssembledVirus-Like Particles from Wild-Type and Mutant Human Hepatitis B VirusCapsidProteins

F. Suk, M. Cajimat, C. Shih, 2003, Journal of Virology.

Establishment and characterization of a new human hepatocellular carcinoma cell line

K. Isselbacher, J. Wands, H. Goodman, 1984, In Vitro.

Virion Secretion of Hepatitis B Virus Naturally Occurring Core Antigen Variants

C. Shih, Shu-Fan Chou, Szu-Yao Wu, 2020, Cells.

Persistence of Hepatitis B Virus DNA and the Tempos between Virion Secretion and Genome Maturation in a Mouse Model

C. Shih, Szu-Yao Wu, Ya-Shu Chang, 2019, Journal of Virology.

Isolation of a transforming sequence from a human bladder carcinoma cell line

R. Weinberg, C. Shih, 1982, Cell.

Influence of a Putative Intermolecular Interaction between Core and the Pre-S1 Domain of the Large Envelope Protein on Hepatitis B Virus Secretion

S. Le Pogam, C. Shih, 2002, Journal of Virology.

Low-Level Secretion of Human Hepatitis B Virus Virions Caused by Two Independent, Naturally Occurring Mutations (P5T and L60V) in the Capsid Protein

S. Le Pogam, C. Shih, G. K. Sahu, 2000, Journal of Virology.

A Frequent, Naturally Occurring Mutation (P130T) of Human Hepatitis B Virus Core Antigen Is Compensatory for Immature Secretion Phenotype of Another Frequent Variant (I97L)

C. Shih, T. T. Yuan, 2000, Journal of virology.

Preferred translation of human hepatitis B virus polymerase from core protein- but not from precore protein-specific transcript

S. Tahara, J. Ou, J. Ou, 1990, Journal of virology.

MicroRNA-130a can inhibit hepatitis B virus replication via targeting PGC1α and PPARγ

M. Tao, Jyun-Yuan Huang, Hung-Lin Chen, 2015, RNA.

The Dual Role of an ESCRT-0 Component HGS in HBV Transcription and Naked Capsid Secretion

Jyun-Yuan Huang, C. Shih, Shu-Fan Chou, 2015, PLoS pathogens.

HBV maintains electrostatic homeostasis by modulating negative charges from phosphoserine and encapsidated nucleic acids

P. Su, Chih-Yin Lee, C. Shih, 2016, Scientific Reports.

Virion Secretion of Naturally Occurring Core Antigen Variants of Human Hepatitis B Virus

C. Shih, 2012 .

Potent inhibition of human Hepatitis B virus replication by a host factor Vps4.

C. Shih, Min-Hui Lin, Pong Kian Chua, 2006, Virology.

Exposure of RNA Templates and Encapsidation of Spliced Viral RNA Are Influenced by the Arginine-Rich Domain of Human Hepatitis B Virus Core Antigen (HBcAg 165-173)

S. Le Pogam, C. Shih, P. K. Chua, 2005, Journal of Virology.

Nucleolar Localization of Human Hepatitis B Virus Capsid Protein

C. Shih, B. Ning, 2004, Journal of Virology.

Coexistence of Two Distinct Secretion Mutations (P5T and I97L) in Hepatitis B Virus Core Produces a Wild-Type Pattern of Secretion

Y. Wen, C. Shih, P. K. Chua, 2003, Journal of Virology.

Subtype-Independent Immature Secretion and Subtype-Dependent Replication Deficiency of a Highly Frequent, Naturally Occurring Mutation of Human Hepatitis B Virus Core Antigen

C. Shih, P. Tai, T. T. Yuan, 1999, Journal of Virology.

The mechanism of natural occurrence of two closely linked HBV precore predominant mutations.

A. Faruqi, J. Shih, C. Shih, 1995, Virology.

Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin.

R. Weinberg, B. Shilo, M. Goldfarb, 1979, Proceedings of the National Academy of Sciences of the United States of America.

A Defective Interference-Like Phenomenon of Human Hepatitis B Virus in Chronic Carriers

Ding‐Shinn Chen, C. Shih, Min-Hui Lin, 1998, Journal of Virology.

CRM1-spike-mediated nuclear export of hepatitis B virus encapsidated viral RNA.

M. Hwang, C. Shih, Ching-Shu Suen, 2022, Cell reports.

Testing an Electrostatic Interaction Hypothesis of Hepatitis B Virus Capsid Stability by Using an In Vitro Capsid Disassembly/Reassembly System

P. Su, C. Shih, P. K. Chua, 2009, Journal of Virology.

Functional Characterization of Naturally Occurring Variants of Human Hepatitis B Virus Containing the Core Internal Deletion Mutation

C. Shih, Min-Hui Lin, T. T. Yuan, 1998, Journal of Virology.

Replication-defective missense mutations within the terminal protein and spacer/intron regions of the polymerase gene of human hepatitis B virus.

A. Faruqi, C. Shih, J. Israel, 1991, Virology.

Out-of-frame versus in-frame core internal deletion variants of human and woodchuck hepatitis B viruses.

B. Tennant, J. Gerin, C. Shih, 2002, Virology.

3.5Å cryoEM Structure of Hepatitis B Virus Core Assembled from Full-Length Core Protein

Xuekui Yu, Lei Jin, J. Jih, 2013, PloS one.

A nuanced role of the small loop of hepatitis B virus small envelope protein in virion morphogenesis and secretion

C. Shih, Shu-Fan Chou, Chih-Hsu Chang, 2021, Journal of biomedical science.

cis rescue of a mutated reverse transcriptase gene of human hepatitis B virus by creation of an internal ATG

C. Shih, S. Roychoudhury, 1990, Journal of virology.

Nucleic Acid Chaperone Activity Associated with the Arginine-Rich Domain of Human Hepatitis B Virus Core Protein

P. Su, C. Shih, An-Ting Liou, 2013, Journal of Virology.

Pro-205 of large hepatitis delta antigen and Pro-62 of major hepatitis B surface antigen influence the assembly of different genotypes of hepatitis D virus.

Hsei-Wei Wang, C. Su, C. Shih, 2010, The Journal of general virology.

Emerging New Therapies for Viral Hepatitis

P. Su, C. Shih, 2019, Viral Hepatitis in Children.

Control and Eradication Strategies of Hepatitis B Virus.

Jyun-Yuan Huang, C. Shih, Shu-Fan Chou, 2016, Trends in microbiology.

A cis/trans genetic test for pleiotropic phenotypes associated with a frequent naturally occurring mutation at amino acid 97 of HBV core protein.

C. Shih, T. Yuan, 2004, Methods in molecular medicine.

Testing the Balanced Electrostatic Interaction Hypothesis of Hepatitis B Virus DNA Synthesis by Using an In Vivo Charge Rebalance Approach

C. Shih, Ching-Shu Suen, P. K. Chua, 2009, Journal of Virology.

A one-filter-three-probe assay for defective interference (DI) effects of naturally occurring core internal deletion (CID) variants of human hepatitis B virus.

C. Shih, T. Yuan, 2004, Methods in molecular medicine.

MicroRNA-22 Can Reduce Parathymosin Expression in Transdifferentiated Hepatocytes

Jyun-Yuan Huang, Hung-Lin Chen, C. Shih, 2012, PloS one.

Hepatitis B virus propagated in a rat hepatoma cell line is infectious in a primate model.

J. Shih, C. Shih, M. Yu, 1990, Virology.

Oncogene from human EJ bladder carcinoma is located on the short arm of chromosome 11.

R. Weinberg, U. Francke, C. Shih, 1983, Science.

Immunodeficient Mouse Models with Different Disease Profiles by In Vivo Infection with the Same Clinical Isolate of Enterovirus 71

P. Tu, Chun-Che Liao, Chih-Shin Chang, 2014, Journal of Virology.

Feedback regulation of IFN‐α/β signaling by Axl receptor tyrosine kinase modulates HBV immunity

Ding‐Shinn Chen, P. Liu, H. Chuang, 2015, European journal of immunology.

Nuclear Export and Import of Human Hepatitis B Virus Capsid Protein and Particles

Wen-Chang Chang, Young-Sun Lin, Young-Sun Lin, 2010, PLoS pathogens.

Structural comparisons of hepatitis B core antigen particles with different C-terminal lengths.

Z. Zhou, Aguang Dai, Kunpeng Li, 2010, Virus research.

Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model

Chun-Che Liao, Chih-Shin Chang, C. Shih, 2019, Journal of Biomedical Science.

A Homokaryon Assay for Nucleocytoplasmic Shuttling Activity of HBV Core Protein.

C. Shih, Ching-Chun Yang, Hung-Cheng Li, 2017, Methods in molecular biology.

Novel and frequent mutations of hepatitis B virus coincide with a major histocompatibility complex class I-restricted T-cell epitope of the surface antigen

C. S. Lee, C. Yang, T. Kuo, 1997, Journal of virology.

Significance of hepatitis B virus capsid dephosphorylation via polymerase

C. Shih, Chih-Hsu Chang, 2024, Journal of biomedical science.

Infrequent mutation of p53 gene in hepatitis B virus positive primary hepatocellular carcinomas.

C. S. Lee, S. Hosono, M. Chou, 1993, Oncogene.