S. Harriman

发表

Identification of saturated and unsaturated fatty acids released during microsomal incubations

U. Argikar, J. Bushee, Guiqing Liang, 2014, Xenobiotica; the fate of foreign compounds in biological systems.

The development of a higher throughput reactive intermediate screening assay incorporating micro-bore liquid chromatography-micro-electrospray ionization-tandem mass spectrometry and glutathione ethyl ester as an in vitro conjugating agent.

J. Boyd, M. Cole, J. Barberia, 2004, Journal of pharmaceutical and biomedical analysis.

Strategies and chemical design approaches to reduce the potential for formation of reactive metabolic species.

U. Argikar, J. Mangold, S. Harriman, 2011, Current topics in medicinal chemistry.

Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors.

A. Coxon, D. Whittington, A. Tasker, 2008, Journal of medicinal chemistry.

Inhibition of cytochrome P450 enzymes and biochemical aspects of mechanism-based inactivation (MBI).

S. Harriman, A. Kamel, 2013, Drug discovery today. Technologies.

Detection and identification of carcinogen-peptide adducts by nanoelectrospray tandem mass spectrometry

J. A. Hill, S. Tannenbaum, S. Harriman, 1998, Journal of the American Society for Mass Spectrometry.

Formation of cyclopropanone during cytochrome P450-catalyzed N-dealkylation of a cyclopropylamine.

R. Hanzlik, Y. Koen, C. L. Shaffer, 2002, Journal of the American Chemical Society.

Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation.

Ling Wang, Kelly Regal, Sesha Neervannan, 2008, Journal of medicinal chemistry.

An interface for direct analysis of (14)c in nonvolatile samples by accelerator mass spectrometry.

B. Hughey, R. Shefer, S. Tannenbaum, 2004, Analytical chemistry.

Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis.

M. Morrison, A. Coxon, D. Whittington, 2008, Journal of medicinal chemistry.

Oxidative ipso Substitution of 2,4-Difluoro-benzylphthalazines: Identification of a Rare Stable Quinone Methide and Subsequent GSH Conjugate

F. Lombardo, U. Argikar, Amanda L. Cirello, 2012, Drug Metabolism and Disposition.

Pharmacological characterization of CP-547,632, a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for cancer therapy.

F. Rastinejad, W. Roberts, Eugenia Floyd, 2003, Cancer research.

Identification of a Novel N-Carbamoyl Glucuronide: In Vitro, In Vivo, and Mechanistic Studies

U. Argikar, V. Hosagrahara, Suzie Ferreira, 2010, Drug Metabolism and Disposition.

Comprehensive Assessment of Human Pharmacokinetic Prediction Based on In Vivo Animal Pharmacokinetic Data, Part 2: Clearance

Franco Lombardo, Giuliano Berellini, F. Lombardo, 2013, Journal of clinical pharmacology.

A comprehensive listing of bioactivation pathways of organic functional groups.

Ernesto Callegari, Iain Gardner, A. Kalgutkar, 2005, Current drug metabolism.

Discovery and pharmacologic characterization of CP-724,714, a selective ErbB2 tyrosine kinase inhibitor.

R. D. Connell, L. Pustilnik, Joel Morris, 2007, Cancer research.

Microsoft Word-18199777-file00

U. Argikar, V. Hosagrahara, Suzie Ferreira, 2009 .

Comprehensive Assessment of Human Pharmacokinetic Prediction Based on In Vivo Animal Pharmacokinetic Data, Part 1: Volume of Distribution at Steady State

Franco Lombardo, R Scott Obach, Giuliano Berellini, 2013, Journal of clinical pharmacology.

Strategies for the Identification of Unusual and Novel Metabolites Using Derivatization, Hydrogen–deuterium Exchange (HDX), and Liquid Chromatography‐nuclear Magnetic Resonance (LC‐NMR) Spectroscopy Techniques

C. Prakash, S. Harriman, A. Kamel, 2014 .

Evaluation of indazole-based compounds as a new class of potent KDR/VEGFR-2 inhibitors.

A. Coxon, D. Whittington, A. Polverino, 2008, Bioorganic & medicinal chemistry letters.

In vitro-in vivo correlation for intrinsic clearance for CP-409,092 and sumatriptan: a case study to predict the in vivo clearance for compounds metabolized by monoamine oxidase

R. Obach, S. Harriman, A. Kamel, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

Quantitation of total antibody (tAb) from antibody drug conjugate (ADC) PYX-201 in rat and monkey plasma using an enzyme-linked immunosorbent assay (ELISA) and its application in preclinical studies

J. Pinkas, A. Amrite, S. Harriman, 2023, Journal of Pharmaceutical and Biomedical Analysis.