C. Ellison

发表

Solvent Solubility Testing of Cosmetics-Relevant Chemicals: Methodology and Correlation of Water Solubility to In Silico Predictions

N. Hewitt, H. Rothe, A. Schepky, 2017, Journal of Solution Chemistry.

Use of Cytochrome P450-Specific Parameters and Human Biomarker Data To Develop a Human Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Dermal Chlorpyrifos Exposure

J. Olson, J. Knaak, Robin McDougall, 2012 .

The way forward for assessing the human health safety of cosmetics in the eu workshop proceedings.

T. Vanhaecke, V. Rogiers, A. Worth, 2020, Toxicology.

Toxicogenomic analysis of exposure to TCDD, PCB126 and PCB153: identification of genomic biomarkers of exposure to AhR ligands

J. Olson, C. Vezina, Chad M. Vezina, 2010, BMC Genomics.

Comparison of the metabolism of 10 chemicals in human and pig skin explants

D. Zalko, N. Hewitt, L. Debrauwer, 2018, Journal of applied toxicology : JAT.

Measurement of the penetration of 56 cosmetic relevant chemicals into and through human skin using a standardized protocol

E. Fabian, N. Hewitt, H. Rothe, 2019, Journal of applied toxicology : JAT.

Biotransformation of Insecticides

J. Olson, C. Ellison, Alice L. Crane, 2012 .

Internal Threshold of Toxicological Concern (iTTC): Where We Are Today and What Is Possible in the Near Future

A. M. Api, N. Hewitt, R. Becker, 2021, Frontiers in Toxicology.

Use of human liver and EpiSkin™ S9 subcellular fractions as a screening assays to compare the in vitro hepatic and dermal metabolism of 47 cosmetics‐relevant chemicals

N. Hewitt, H. Rothe, A. Schepky, 2020, Journal of applied toxicology : JAT.

Allele and Genotype Frequencies of CYP2B6 and CYP2C19 Polymorphisms in Egyptian Agricultural Workers

J. Olson, P. Lein, Maha A. Tawfik, 2012, Journal of toxicology and environmental health. Part A.

Application of structural and functional pharmacokinetic analogs for physiologically based pharmacokinetic model development and evaluation.

Shengde Wu, C. Ellison, 2020, Regulatory toxicology and pharmacology : RTP.

Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.

M. Cronin, H. Clewell, E. Mombelli, 2022, Regulatory toxicology and pharmacology : RTP.

Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment

A. Piersma, T. Gant, J. Wambaugh, 2022, Archives of Toxicology.

Cosmetics Europe evaluation of 6 in silico skin penetration models

E. Fabian, N. Hewitt, J. Troutman, 2021, Computational Toxicology.

Partition coefficient and diffusion coefficient determinations of 50 compounds in human intact skin, isolated skin layers and isolated stratum corneum lipids.

A. Rolaki, N. Hewitt, J. Manwaring, 2020, Toxicology in vitro : an international journal published in association with BIBRA.

Metabolism of profenofos to 4-bromo-2-chlorophenol, a specific and sensitive exposure biomarker.

F. Farahat, J. Olson, B. McGarrigle, 2013, Toxicology.

Dosimetry considerations for in vivo and in vitro test data and a novel surrogate iTTC approach for read-across based on metabolites

Karen Blackburn, C. A. Ellison, S. B. Stuard, 2019, Computational Toxicology.

Impact of chemical structure on the in vitro hydrolysis of fatty esters of 2-ethylhexanoic acid or 2-ethylhexanol and extrapolation to the in vivo situation.

C. Obringer, C. Ellison, Alex Smith, 2022, Regulatory toxicology and pharmacology : RTP.

Cytochrome P450-specific human PBPK/PD models for the organophosphorus pesticides: chlorpyrifos and parathion.

Corie A Ellison, J. Olson, James B Knaak, 2011, Toxicology.

Comparison of the metabolism of 10 cosmetics‐relevant chemicals in EpiSkin™ S9 subcellular fractions and in vitro human skin explants

N. Hewitt, H. Rothe, A. Schepky, 2019, Journal of applied toxicology : JAT.

Comparison of the Skin Penetration of 3 Metabolically Stable Chemicals Using Fresh and Frozen Human Skin

Martina Klaric, Richard Cubberley, Hélène Duplan, 2017, Skin Pharmacology and Physiology.

Pharmacokinetics and pharmacodynamics of chlorpyrifos in adult male Long-Evans rats following repeated subcutaneous exposure to chlorpyrifos.

J. Olson, P. Lein, C. Ellison, 2011, Toxicology.

Biomarkers of Chlorpyrifos Exposure and Effect in Egyptian Cotton Field Workers

R. Fenske, M. Bonner, W. Anger, 2011, Environmental health perspectives.

Structural and functional pharmacokinetic analogs for physiologically based pharmacokinetic (PBPK) model evaluation

Corie A Ellison, C. Ellison, 2018, Regulatory toxicology and pharmacology : RTP.

Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop

Andrew Worth, Bertrand Desprez, Martina Klaric, 2019, Regulatory toxicology and pharmacology : RTP.

Practical application of the interim internal threshold of toxicological concern (iTTC): a case study based on clinical data

N. Hewitt, A. Najjar, S. Grégoire, 2022, Archives of Toxicology.

Use of a Simple in vitro Test to Assess Loss of Chemical due to Volatility during an in vitro Human Skin Absorption Study

N. Hewitt, H. Rothe, A. Schepky, 2019, Skin Pharmacology and Physiology.

PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos.

R. Browne, M. Bonner, J. Olson, 2012, Toxicology and applied pharmacology.

Human Hepatic Cytochrome P450-Specific Metabolism of the Organophosphorus Pesticides Methyl Parathion and Diazinon

P. Kostyniak, J. Olson, J. Knaak, 2012, Drug Metabolism and Disposition.

Physiologically based pharmacokinetic modeling software

Andreas Schepky, Harvey J. Clewell, C. E. Hack, 2020 .

Metabolism and plasma protein binding of 16 straight- and branched-chain parabens in in vitro liver and skin models.

E. Fabian, N. Hewitt, Manuela Mayer, 2020, Toxicology in vitro : an international journal published in association with BIBRA.

Refine and Strengthen SAR-Based Read-Across by Considering Bioactivation and Modes of Action

Shengde Wu, J. Rose, C. Ellison, 2023, Chemical research in toxicology.

A strategy for systemic toxicity assessment based on non-animal approaches: The Cosmetics Europe Long Range Science Strategy programme.

Bertrand Desprez, Matt Dent, Detlef Keller, 2018, Toxicology in vitro : an international journal published in association with BIBRA.