R. Lakey

发表

Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial

H. H. Jensen, P. Wilding, S. Pocock, 2017, The Lancet.

Lipophilic statins prevent matrix metalloproteinase-mediated cartilage collagen breakdown by inhibiting protein geranylgeranylation

D. Young, T. Cawston, M. Barter, 2010, Annals of the rheumatic diseases.

Paramedic Acute Stroke Treatment Assessment (PASTA): study protocol for a randomised controlled trial

H. Rodgers, L. Shaw, J. Lally, 2019, Trials.

Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption

D. Edwards, C. Pennington, I. Clark, 2005, Arthritis research & therapy.

Evaluation of stroke thrombectomy including patients where IV thrombolysis is contraindicated or has failed: a randomized trial of two novel thrombectomy devices

B. Gregson, G. Ford, R. Simister, 2020, Journal of NeuroInterventional Surgery.

Synergistic Collagenase Expression and Cartilage Collagenolysis Are Phosphatidylinositol 3-Kinase/Akt Signaling-dependent*

A. Rowan, D. Young, T. Cawston, 2008, Journal of Biological Chemistry.

Matrix metalloproteinase 10 promotion of collagenolysis via procollagenase activation: implications for cartilage degradation in arthritis.

A. Rowan, C. Richards, T. Cawston, 2006, Arthritis and rheumatism.

Serum MMP-1 and TIMP-1 levels are increased in patients with psoriatic arthritis and their siblings.

L. Kay, T. Cawston, D. Walker, 2003, Rheumatology.

Acipimox in Mitochondrial Myopathy (AIMM): study protocol for a randomised, double-blinded, placebo-controlled, adaptive design trial of the efficacy of acipimox in adult patients with mitochondrial myopathy

L. Rochester, L. Alcock, S. Del Din, 2022, Trials.

Gingival fibroblasts grown from cyclosporin-treated patients show a reduced production of matrix metalloproteinase-1 (MMP-1) compared with normal gingival fibroblasts, and cyclosporin down-regulates the production of MMP-1 stimulated by pro-inflammatory cytokines.

R. Seymour, J. M. Thomason, T. Sukkar, 2007, Journal of periodontal research.

A novel paradigm for dendritic cells as effectors of cartilage destruction.

J. Isaacs, A. Rowan, C. Hilkens, 2008, Rheumatology.

Sulfasalazine blocks the release of proteoglycan and collagen from cytokine stimulated cartilage and down-regulates metalloproteinases.

T. Cawston, R. Lakey, 2009, Rheumatology.

A Novel in Vitro Model to Investigate Behavior of Articular Chondrocytes in Osteoarthritis

M. Birch, A. McCaskie, A. Sprowson, 2010, The Journal of Rheumatology.

The Journal of Rheumatology Volume 37 , no . 2 Osteoarthritis Model to Investigate Behavior of Articular Chondrocytes in in Vitro

M. Birch, A. McCaskie, A. Sprowson, 2010 .

Baseline serum MMP-3 levels in patients with Rheumatoid Arthritis are still independently predictive of radiographic progression in a longitudinal observational cohort at 8 years follow up

C. Potter, J. Isaacs, I. Griffiths, 2012, Arthritis Research & Therapy.

Effect of an Enhanced Paramedic Acute Stroke Treatment Assessment on Thrombolysis Delivery During Emergency Stroke Care

H. Rodgers, L. Shaw, C. Price, 2020, JAMA neurology.

Dual bronchodilators in Bronchiectasis study (DIBS): protocol for a pragmatic, multicentre, placebo-controlled, three-arm, double-blinded, randomised controlled trial studying bronchodilators in preventing exacerbations of bronchiectasis

J. Wason, C. Haworth, A. Hill, 2023, BMJ open.

Synergistic Collagenase Expression and Cartilage Collagenolysis Are Phosphatidylinositol 3-Kinase/Akt Signaling-dependent*

A. Rowan, T. Cawston, R. Lakey, 2008, Journal of Biological Chemistry.

Newcastle University E-prints Citation for Item: Baseline Serum Mmp-3 Levels in Patients with Rheumatoid Arthritis Are Still Independently Predictive of Radiographic Progression in a Longitudinal Observational Cohort at 8 Years Follow Up

C. Potter, J. Isaacs, I. Griffiths, 2022 .