T. Sadowski

发表

Cathepsin A Mediates Ventricular Remote Remodeling and Atrial Cardiomyopathy in Rats With Ventricular Ischemia/Reperfusion

U. Schotten, M. Böhm, P. Sanders, 2019, JACC. Basic to translational science.

Minocycline inhibits the production of inducible nitric oxide synthase in articular chondrocytes.

T. Sadowski, J. Steinmeyer, 2001, The Journal of rheumatology.

Inhibition of CatA: an emerging strategy for the treatment of heart failure.

C. Buning, H. Schreuder, H. Ruetten, 2013, Future medicinal chemistry.

Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy

Hetal S. Shah, D. Gordin, G. King, 2019, Diabetes Care.

Proteomic Profiling of Cardiomyocyte-Specific Cathepsin A Overexpression Links Cathepsin A to the Oxidative Stress Response.

J. Gassenhuber, O. Schilling, D. Linz, 2016, Journal of proteome research.

Effects of polysulfated glycosaminoglycan and triamcinolone acetonid on the production of proteinases and their inhibitors by IL-1alpha treated articular chondrocytes.

T. Sadowski, J. Steinmeyer, 2002, Biochemical pharmacology.

Effects of non-steroidal antiinflammatory drugs and dexamethasone on the activity and expression of matrix metalloproteinase-1, matrix metalloproteinase-3 and tissue inhibitor of metalloproteinases-1 by bovine articular chondrocytes.

T. Sadowski, J. Steinmeyer, 2001, Osteoarthritis and cartilage.

Manner and Associates with the Cell Surface Myeloid Cells in an Adhesion-Dependent Matrix Metalloproteinase-19 Is Expressed in

R. Sedláček, C. Kolb, T. Sadowski, 2002 .

MMP19 Is Essential for T Cell Development and T Cell-Mediated Cutaneous Immune Responses

Markus S. Mueller, P. Schirmacher, R. Sedláček, 2008, PloS one.

Differential effects of nonsteroidal antiinflammatory drugs on the IL-1 altered expression of plasminogen activators and plasminogen activator inhibitor-1 by articular chondrocytes

T. Sadowski, J. Steinmeyer, 2002, Inflammation Research.

Effects of tetracyclines on the production of matrix metalloproteinases and plasminogen activators as well as of their natural inhibitors, tissue inhibitor of metalloproteinases-1 and plasminogen activator inhibitor-1

T. Sadowski, J. Steinmeyer, 2001, Inflammation Research.

Matrix metalloproteinase-19 expression in normal and diseased skin: dysregulation by epidermal proliferation.

R. Sedláček, B. Havlíčková, E. Proksch, 2003, The Journal of investigative dermatology.

Crystal structure of cathepsin A, a novel target for the treatment of cardiovascular diseases.

C. Buning, H. Schreuder, Katja Kroll, 2014, Biochemical and biophysical research communications.

Cellular Cholesterol Depletion Triggers Shedding of the Human Interleukin-6 Receptor by ADAM10 and ADAM17 (TACE)*

Stefan Rose-John, S. Rose-John, D. Hartmann, 2003, Journal of Biological Chemistry.

Monday, 27 August 2012

V. V. Ivanenko, E. A. Medvedeva, Michail I. Papafaklis, 2012 .

Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice

M. Mayr, M. Böhm, C. Maack, 2020, Journal of Biological Chemistry.

Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction

William J. Israelsen, M. V. Vander Heiden, A. Kannt, 2017, Nature Medicine.

Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis

KyeongJin Kim, L. Qiang, Junjie Yu, 2021, Science Translational Medicine.

The murine ortholog of matrix metalloproteinase 19: its cloning, gene organization, and expression.

R. Sedláček, M. S. Mueller, C. Kolb, 2000, Gene.

Tolerability, safety, and pharmacokinetics of the novel cathepsin A inhibitor SAR164653 in healthy subjects

H. Ruetten, Z. Lukacs, J. Tillner, 2016, Clinical pharmacology in drug development.

Cathepsin A mediates susceptibility to atrial tachyarrhythmia and impairment of atrial emptying function in Zucker diabetic fatty rats.

Dominik Linz, Michael Böhm, Ulrich Schotten, 2016, Cardiovascular research.

Matrix Metalloproteinase-19 Is Expressed in Myeloid Cells in an Adhesion-Dependent Manner and Associates with the Cell Surface1

R. Sedláček, C. Kolb, T. Sadowski, 2002, The Journal of Immunology.

Hyperpolarized pyruvate to measure the influence of PKM2 activation on glucose metabolism in the healthy kidney

C. Laustsen, L. B. Bertelsen, S. Ruf, 2021, NMR in biomedicine.

Matrix metalloproteinase 19 processes the laminin 5 gamma 2 chain and induces epithelial cell migration

B. Titz, A. Ludwig, R. Sedláček, 2005, Cellular and Molecular Life Sciences CMLS.

Matrix metalloproteinase 19 regulates insulin-like growth factor-mediated proliferation, migration, and adhesion in human keratinocytes through proteolysis of insulin-like growth factor binding protein-3.

R. Sedláček, T. Sadowski, S. Dietrich, 2003, Molecular biology of the cell.

Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels

J. Gassenhuber, O. Schilling, A. Petrera, 2016, Journal of Translational Medicine.

Novel β-amino acid derivatives as inhibitors of cathepsin A.

C. Buning, G. Horstick, H. Schreuder, 2012, Journal of medicinal chemistry.

23. The Discovery of Cathepsin A Inhibitors: A Project-Adapted Fragment Approach Based on HTS Results

C. Buning, G. Horstick, H. Schreuder, 2016 .

Long‐term severe diabetes only leads to mild cardiac diastolic dysfunction in Zucker diabetic fatty rats

D. Linz, H. Juretschke, M. Bilsen, 2012, European journal of heart failure.

Activity of MMP-19 inhibits capillary-like formation due to processing of nidogen-1

B. Titz, R. Sedláček, T. Sadowski, 2004, Cellular and Molecular Life Sciences CMLS.

Matrix metalloproteinase-19 expression in keratinocytes is repressed by transcription factors Tst-1 and Skn-1a: implications for keratinocyte differentiation.

R. Paus, R. Sedláček, I. Beck, 2007, The Journal of investigative dermatology.