J. Dixon

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Genetic background has a major effect on the penetrance and severity of craniofacial defects in mice heterozygous for the gene encoding the nucleolar protein treacle

M. Dixon, J. Dixon, 2004, Developmental dynamics : an official publication of the American Association of Anatomists.

Facial clefting in Tp63 deficient mice results from altered Bmp4, Fgf8 and Shh signaling.

M. Dixon, J. Dixon, Helen A. Thomason, 2008, Developmental biology.

Mammalian Neurogenesis Requires Treacle-Plk1 for Precise Control of Spindle Orientation, Mitotic Progression, and Maintenance of Neural Progenitor Cells

M. Dixon, D. Sakai, P. Trainor, 2012, PLoS genetics.

SARS-CoV-2 Testing of 11,884 Healthcare Workers at an Acute NHS Hospital Trust in England: A Retrospective Analysis

D. Lendrem, B. Payne, D. Price, 2021, Frontiers in Medicine.

SARS-CoV-2 Testing of 11,884 Healthcare Workers at an Acute NHS Hospital Trust in England: A Retrospective Analysis

D. Lendrem, E. Hunter, Y. Taha, 2020, Frontiers in Medicine.

Targeted Deletion of mek5 Causes Early Embryonic Death and Defects in the Extracellular Signal-Regulated Kinase 5/Myocyte Enhancer Factor 2 Cell Survival Pathway

Chun Guo, A. Merritt, R. Boot-Handford, 2005, Molecular and Cellular Biology.

Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function

Earl F. Glynn, E. Glynn, M. Dixon, 2008, Nature Medicine.

A conserved Pbx-Wnt-p63-Irf6 regulatory module controls face morphogenesis by promoting epithelial apoptosis.

Matthew J. Anderson, M. Depew, M. Dixon, 2011, Developmental cell.

Tcof1 acts as a modifier of Pax3 during enteric nervous system development and in the pathogenesis of colonic aganglionosis.

M. Dixon, P. Trainor, J. Dixon, 2013, Human molecular genetics.

and in the pathogenesis of colonic aganglionosis

M. Dixon, P. Trainor, J. Dixon, 2013 .

Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence

M. Dixon, R. Jiang, R. Richardson, 2009, Human molecular genetics.

Narrowing the position of the Treacher Collins syndrome locus to a small interval between three new microsatellite markers at 5q32-33.1.

K. Klinger, G. Landes, T. Houseal, 1993, American journal of human genetics.

Clinical Management of Viral Hemorrhagic Fevers

E. Ong, J. Dixon, 2014, Current Treatment Options in Infectious Diseases.

Importance of antimicrobial stewardship to the English National Health Service

C. Duncan, J. Dixon, Jill Dixon, 2014, Infection and drug resistance.

Defects in middle ear cavitation cause conductive hearing loss in the Tcof1 mutant mouse.

J. Linden, M. Dixon, A. Tucker, 2010, Human molecular genetics.

Increased levels of apoptosis in the prefusion neural folds underlie the craniofacial disorder, Treacher Collins syndrome.

M. Dixon, R. Fässler, C. Brakebusch, 2000, Human molecular genetics.

A quantitative method for defining high-arched palate using the Tcof1(+/-) mutant mouse as a model.

M. Dixon, P. Trainor, H. Kurosaka, 2016, Developmental biology.

Balancing neural crest cell intrinsic processes with those of the microenvironment in Tcof1 haploinsufficient mice enables complete enteric nervous system formation.

M. Dixon, P. Trainor, J. Dixon, 2012, Human molecular genetics.

Identification of mutations in TCOF1: Use of molecular analysis in the pre‐ and postnatal diagnosis of Treacher Collins syndrome

M. Dixon, A. Bottani, K. Temple, 2004, American journal of medical genetics. Part A.

Another face of the Treacher Collins syndrome (TCOF1) gene: identification of additional exons.

M. Dixon, B. Valdez, D. Henning, 2004, Gene.

Mutations in the Treacher Collins syndrome gene lead to mislocalization of the nucleolar protein treacle.

M. Dixon, J. Dixon, K. Marsh, 1998, Human molecular genetics.

Treacher Collins syndrome may result from insertions, deletions or splicing mutations, which introduce a termination codon into the gene.

R. Hennekam, J. Wasmuth, M. Dixon, 1996, Human molecular genetics.

A YAC contig encompassing the Treacher Collins syndrome critical region at 5q31.3-32.

J. Riley, J. Wasmuth, M. Dixon, 1994, American Journal of Human Genetics.

p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome

C. Missero, H. van Bokhoven, Huiqing Zhou, 2012, Human molecular genetics.

Cytokeratin 15 Marks Basal Epithelia in Developing Ureters and Is Upregulated in a Subset of Urothelial Cell Carcinomas

H. Denley, A. Woolf, F. Marriage, 2013, PloS one.

Enhanced ectodysplasin‐A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form

M. Dixon, D. Headon, C. Clowes, 2008, Human mutation.

Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice.

G. Dotto, Evelyn N. Kouwenhoven, H. van Bokhoven, 2010, The Journal of clinical investigation.

Rare syndromes of the head and face: mandibulofacial and acrofacial dysostoses

M. Dixon, P. Trainor, J. Dixon, 2017, Wiley interdisciplinary reviews. Developmental biology.

Cloning of the human heparan sulfate-N-deacetylase/N-sulfotransferase gene from the Treacher Collins syndrome candidate region at 5q32-q33.1.

P. Scambler, J. Wasmuth, M. Dixon, 1995, Genomics.

Candidate Genes for Nonsyndromic Cleft Palate Detected by Exome Sequencing

A. Hoischen, M. Nöthen, C. Gilissen, 2017, Journal of dental research.

Exome sequence identifies RIPK4 as the Bartsocas-Papas syndrome locus.

S. Bhaskar, S. Sinha, J. Murray, 2012, American journal of human genetics.

p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate

H. Stunnenberg, S. V. van Heeringen, S. Sinha, 2017, PLoS genetics.

The Treacher Collins syndrome (TCOF1) gene product is involved in pre-rRNA methylation.

Michael J Dixon, M. Dixon, B. Valdez, 2005, Human molecular genetics.

The Treacher Collins syndrome (TCOF1) gene product is involved in ribosomal DNA gene transcription by interacting with upstream binding factor.

Michael J Dixon, M. Dixon, B. Valdez, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Sequence analysis, identification of evolutionary conserved motifs and expression analysis of murine tcof1 provide further evidence for a potential function for the gene and its human homologue, TCOF1.

R. Shiang, M. Dixon, K. Hovanes, 1997, Human molecular genetics.

Positional cloning of a gene involved in the pathogenesis of Treacher Collins syndrome

J. Wasmuth, M. Dixon, S. Loftus, 1996, Nature Genetics.

Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development

Mihaela E. Sardiu, S. Swanson, J. Unruh, 2021, bioRxiv.

Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch

Michael J Dixon, R. Boot-Handford, M. Dixon, 2006, Nature Genetics.

Periderm: Life-cycle and function during orofacial and epidermal development.

M. Dixon, J. Dixon, N. Hammond, 2017, Seminars in cell & developmental biology.

Transcriptional map of the Treacher Collins candidate gene region.

J. Wasmuth, M. Dixon, S. Loftus, 1996, Genome research.

Genetic and physical mapping of the Treacher Collins syndrome locus: refinement of the localization to chromosome 5q32-33.2.

K. Klinger, G. Landes, M. L. Le Beau, 1992, Human molecular genetics.

Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome

B. Spencer‐Dene, D. Acampora, C. Missero, 2012, EMBO molecular medicine.

Identification and cloning of a novel cellular protein Naf1, Nef‐associated factor 1, that increases cell surface CD4 expression 1

Tohru Kimura, M. Dixon, M. Fukushi, 1999 .

Mutations in genes encoding subunits of RNA polymerases I and III cause Treacher Collins syndrome

L. Hoefsloot, D. Wieczorek, A. Haeringen, 2011, Nature Genetics.

Treacher Collins syndrome: etiology, pathogenesis and prevention

Michael J Dixon, M. Dixon, P. Trainor, 2009, European Journal of Human Genetics.

Systematic analysis of copy number variants of a large cohort of orofacial cleft patients identifies candidate genes for orofacial clefts

M. Oti, M. Rubini, Huiqing Zhou, 2015, Human Genetics.

Identification of the complete coding sequence and genomic organization of the Treacher Collins syndrome gene.

P. Scambler, A. Brass, M. Dixon, 1997, Genome research.

Tcof1/Treacle is required for neural crest cell formation and proliferation deficiencies that cause craniofacial abnormalities

M. Dixon, P. Trainor, L. Sandell, 2006, Proceedings of the National Academy of Sciences.

Novel mutations in LRP6 highlight the role of WNT signaling in tooth agenesis

L. Vissers, A. Hoischen, R. Pfundt, 2016, Genetics in Medicine.

Prevention of Treacher Collins syndrome craniofacial anomalies in mouse models via maternal antioxidant supplementation

M. Dixon, D. Sakai, P. Trainor, 2016, Nature Communications.

UNIVERSITY OF NAPOLI FEDERICO II Doctorate School in Molecular Medicine Doctorate Program in Genetics and Molecular Medicine Coordinator: Prof. Lucio Nitsch XXVII Cycle “Molecular mechanisms at the basis of epidermal defects and skin fragility in AEC syndrome”

Salvatore, H. Bokhoven, C. Missero, 2015 .

p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis

F. Brancati, C. Missero, A. Costanzo, 2015, Experimental dermatology.

Temporal and spatial expression of Pax9 and Sonic hedgehog during development of normal mouse palates and cleft palates in TGF-β3 null embryos

S. O'Kane, M. Dixon, M. Ferguson, 2007 .

organization of the Treacher Collins syndrome gene. Identification of the complete coding sequence and genomic

I. Anderson, J. Dixon, S. Edwards, 2011 .

P0675 PREDICTORS OF MORTALITY AND MORBIDITY IN CLOSTRIDIUM DIFFICILE INFECTION

J. Dixon, B. Menezes, M. Abbas, 2009 .

Predictors of mortality and morbidity in Clostridium difficile infection.

J. Dixon, B. Menezes, J. Dixon, 2009 .

Characterization of the nucleolar gene product, treacle, in Treacher Collins syndrome.

E. Jabs, M. Dixon, J. Dixon, 2000, Molecular biology of the cell.